New Horizons in Ophthalmology

Tübingen - June 15th – 17th, 2020

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Agenda

Monday June 15th, 2020

13:00-13:20 Welcome by the organisers
M. Ueffing and U. Bartz-Schmidt
13:20-13:50 Keynote Lecture
How genetic variants contribute to AMD phenotypes
Anand Swaroop
13:50-14:00 Participatory Medicine: The Patient View
Franz Badura

New Developments in AMD

Chairs: Caroline Klaver & Sascha Fauser

14:00-14:25 Diagnostic Risks Pathomechanisms and Endpoints in AMD
Caroline Klaver
14:25-14:50 Targeting AMD pathomechanisms for Therapy development
Sascha Fauser
14:50-15:15 Serum biomarkers & organ-on-a-chip for AMD
Anneke Den Hollander
15:15-16:00 Coffee Break

New Developments in retinal pathogenesis

Chairs: Anneke den Hollander & Simon Clark

16:00-16:25 The Role of Complement Factor H related proteins in AMD
Simon Clark
16:25-16:50 Microglia and retinal Inflammation
Thomas Langmann
16:50-17:00 Regulating Proteostasis in Photoreceptors
Flashlight: Blanca Arango-Gonzalez
17:00-17:10 Sorapazan: An EU clinical study on Stargardt’s Disease
Flashlight: Tobias Peters
17:10-17:35 Oxidate stress in AMD pathogenesis
Kai Kaarniranta
17:35-18:05 Restoring vision at the retinal and cortical levels
Serge Picaud
18:05-18:30 Title: tbd
Jose Sahel
from 18:30 Reception @ Kerstan Atrium

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Tuesday June 16th, 2020

New Developments in Vision Research I

Chairs: Katrin Franke & Thomas Euler

09:00-09:25 Regenerating human photoreceptors
Volker Busskamp
09:25-09:50 A systems view on ciliopathies
Ronald Roepman
09:50-10:15 Ablation of Phosphoinositide 5’-Phosphatase INPP5E prevents Disc Morphogenesis
Wolfgang Baehr
10:15-11:00 Coffee Break
11:00-11:25 Ionic Mechanisms in Intracellular Signaling in the RPE in response to Complement Stimulation
Olaf Strauss
11:25-11:50 Genetic Syndromes with Retinal Involvement
Irene Maumenee
11:50-12:15 Precision Genome Surgery for Imprecision Medicine
Steven Tsang
12:15-14:00 Lunch @ Kerstan Atrium

New Developments in Vision Research II

Chairs: Frank Schaeffel & Bernd Wissinger

14:00-14:25 A horse of another colour: equine recurrent uveitis
Cornelia Deeg
14:25-14:50 Proteostasis in the neuroretina
Mike Cheetham
14:50-15:15 Pharmacotherapy for Stargardt disease
Hendrik Scholl
15:15-16:00 Coffee Break
16:00-16:25 Restoring vision with gene and cell therapy
Deniz Dalkara
16:25-16:35 What the eye tells the brain: Visual feature extraction in the retina
Flashlight: Katrin Franke
16:35-16:45 Retina on a Chip
Flashlight: Stefan Liebau
16:45-17:10 Two-Photon Ophthalmoscopy and its potential for clinical application
Christina Schwarz
17:10-17:35 Drug and gene delivery, glucoses and mineralocorticoid pathways in the retina
Francine Behar-Cohen
17:35-17:45 A patient’s perspective on developing retinal therapies
Christina Fasser
from 19:00 Dinner @ Museum

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Wednesday June 17th, 2020

New Developments in Diagnostic and Therapy

Chairs: Sarah Coupland & U. Bartz-Schmidt

08:30-08:55 Molecular Basis of Lymphoma therapy
Christian Junghanss
08:55-09:20 Molecular genetics of vitreo-retinal lymphoma
Falko Fend
09:20-09:30 Pre-therapeutic differentiation of vitreo-retinal lymphoma
Flashlight: Ulrich Bartz-Schmidt
09:30-09:40 Uveal melanoma metastasis - still a secret?
Flashlight: Daniela Süsskind
09:40-10:05 Molecular genetics of uveal melanoma
Sarah Coupland
10:05-10:30 Coffee Break
10:30-10:55 Why is the treatment method not decisive for the metastasis of the malignant choroidal melanoma?
Heinrich Heimann
10:55-11:20 Reduction of mortality in uveal melanoma. Dream or reality?
Nikos Bechrakis
11:20-11:45 Upcoming Challenges of Diabetic retinopathy
Focke Ziemssen
11:45-11:55 German national cohort study (NAKO) - detection of retinal findings
Flashlight: Alexandra Schweig
11:55-12:20 Which retinal dystrophies are suitable for gene therapy and why?
Claudia Priglinger
12:20-13:20 Lunch @ Kerstan Atrium
13:20-13:45 Non-viral transposon-based gene therapy – the efficient alternative approach escaping the immune system
Gabrielle Thumann
13:45-14:10 Genetherapy, the next steps ahead?
Dominik Fischer
14:10-14:35 Scotopic and photopic chromatic kampimetry of the pupille?
Katarina Stingl
14:35-15:00 Next steps in the evolution of artificial vision
Peter Walter
15:00-15:15 Summary & Farewell
by the organizers
from 15:15 “Swabian Maultaschen 2 Go”

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Agenda NHIO2020

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