- Name and Nationality
Mengchan Sun (China)
- Early Stage Researcher at University of Madrid, Spain (Partner 04)
- Start date:
- Principal Investigator:
Role of ocular aberrations on accommodation dynamics
While it is well accepted that accommodation occurs by reshaping of the crystalline lens to focus near and far objects (and presbyopia occurs by the loss of the crystalline lens ability to accommodate), a complete understanding of the accommodative mechanism is lacking. The attempts to restore accommodation with accommodative intraocular lenses makes the need of these understanding critical. Accommodation is normally monitored by subjective measurements or measurement of the accommodative response (with dynamic photorefraction or Hartmann-Shack aberrometry). However, important aspects are missing in the understanding of the relationship between the physical changes in the crystalline lens and accommodative response, primarily limited by the difficulties of achieving quantitative data of the geometry and structure of the crystalline lens in vivo. Our laboratory has pioneered quantitative imaging techniques of the crystalline lens (both shape and gradient index), based on quantitative high-speed, high-resolution anterior segment spectral Optical Coherence Tomography. The technique has also proved powerful in the evaluation of patients implanted with accommodative IOLs. Custom dynamic aberrometry in combination with sOCT Technologies will be used to link structure and function in accommodation, both in young eyes and patients implanted with IOLs.