Schnichels Lab

Neuroprotection & Drug Delivery

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Sven Schnichels

SurnameSchnichels
First nameSven
NationalityGerman
Present position and titleGroup Leader "Neuroprotection & Drug Delivery"
Dr. rer. nat.

Business address

Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,
Germany

Phone: +49 (0)7071 29-87888
E-mail: sven.schnichels[at]med.uni-tuebingen.de

Academic Education

Year Degree University Field of study
2006 - 2010 PhD (Dr. rer. nat.) Eberhard Karls University, Tübingen, Germany Ophthalmology / Neuroscience
2000 - 2005 Diploma University of Hohenheim, Stuttgart, Germany Biology

Professional Experience

Year Degree University Field of study
2006 - 2010 PhD (Dr. rer. nat.) Eberhard Karls University, Tübingen, Germany Ophthalmology / Neuroscience
2000 - 2005 Diploma University of Hohenheim, Stuttgart, Germany Biology

Professional Activities and Functions

Academic Awards

2016 Poster award: Research Colloquium of the Medical Faculty Tübingen 2016
2015 Poster award: 113. Congress of the Deutsche Ophthalmologische Gesellschaft
2015 Science4Life (Business Plan Competition), Winner Idea + Concept Phase
2015 2. Scientific Prize Verein Rheinisch-Westfälischer Augenärzte
2014 Poster award: 112. Congress of the Deutsche Ophthalmologische Gesellschaft
2014 2. Place: Science2Start from BioRegio STERN Management
2013 1. Place: EYEnovative Research Prize from Novartis
2012 1. Place: NGI (Netherlands Genomics Initiative) Venture Challenge
2011 Poster award: 109. Congress of the Deutsche Ophthalmologische Gesellschaft
2010 Poster award: Tübingen Outer Retina Conference (TORC)
2010 Poster award: Young Researcher Vision Camp 2010

Memberships

Since 2012 Deutsche Ophthalmologische Gesellschaft (DOG)
Since 2010 Association for Research in Vision and Ophthalmology (ARVO)
Since 2010 Neurowissenschaftliche Gesellschaft (NWG)
Since 2007 Society for Neuroscience (SfN)

Additional information

Ad-Hoc Reviewer (Selection)

Investigative Ophthalmology & Visual Science; Scientific Reports; Experimental Eye Research; Organic & Biomolecular Chemistry; Journal of Molecular Neuroscience; Journal of Visualized Experiments; Vision Research; Drug Design, Development and Therapy; Regulatory Toxicology and Pharmacology; Cell and Tissue Research; Cellular Physiology and Biochemistry

Patents

A. Herrmann; J.W. de Vries; M.S. Spitzer; S.O. Schnichels, Means and Methods for Ocular Drug Delivery: PCT/NL2014/050634, EP3057572A1 and US20160346203

Past and Current Funding

2016-2018 Research grant from the SET-Stiftung, Germany
2016-2018 Research grant from the Ministry of Rural Affairs and Consumer Protection Baden-Württemberg, Germany
2016-2019 Research project sponsored by Fluoron, Germany
2014-2017 Research grant (EXIST-Forschungstransfer) from the German federal ministry for economic affairs and energy
2014-2016 Research grant from the SET-Stiftung, Germany
2013-2016 Research grant from the Bundesinstitut für Risikobewertung (BfR), Germany
2013-2014 Intramural research grant of the ƒortüne-Program of the Tübingen medical faculty
2012-2013 Research project sponsored by Clanotech, Sweden
2011-2016 Research project partially supported by Croma, Österreich
2011-2012 Research grant from the Gertrud Kusen-Stiftung

Selected Publications

  1. Schnichels S, Schneider N, Hohenadl C, Hurst J, Schatz A, Januschowski K & Spitzer MS
    Efficacy of two different thiol-modified crosslinked hyaluronate formulations as vitreous replacement compared to silicone oil in a model of retinal detachment.
    PLoS One. 2017 Mar 1;12(3) eCollection 2017.
  2. Kuehn S, Hurst J, Jashari A, Ahrens K, Tsai T, Wunderlich IM, Dick HB, Joachim SC & Schnichels S
    A novel NMDA triggered porcine organ culture induces retinal ganglion cell apoptosis – chances for replacement of animal experiments
    Altern Lab Anim. 2016 Dec;44(6):557-568.
  3. Süsskind D, Hurst J, Rohrbach JM & Schnichels S
    Novel mouse model for primary uveal melanoma: a pilot study.
    Clin Exp Ophthalmol. 2017 Mar;45(2):192-200. doi: 10.1111/ceo.12814. Epub 2016 Sep 7.
  4. Schnichels S, Dorfi T, Schultheiss M, Arango-Gonzalez B, Bartz-Schmidt KU, Januschowski K, Spitzer MS & Ziemssen F
    Ex-vivo-examination of ultrastructural changes in organotypic retina culture using near-infrared imaging and optical coherence tomography.
    Exp Eye Res. 2016 Jun;147:31-6. Epub 2016 Apr 21.
  5. Schultheiss M, Schnichels S, Hermann T, Hurst J, Feldkaemper M, Arango-Gonzalez B, Ueffing M, Bartz-Schmidt KU, Zeck G & Spitzer MS
    Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia.
    PLoS One. 2016 Feb 5;11(2):e0148616. eCollection 2016.
  6. Januschowski K, Mueller S, Krupp C, Spitzer MS, Hurst J, Schultheiss M, Bartz-Schmidt KU, Szurman P & Schnichels S
    Glutamate and hypoxia as a stress model for the isolated perfused vertebrate retina.
    J Vis Exp. 2015 Mar 22;(97).
  7. Schnichels S, Hagemann U, Januschowski K, Hofmann J, Bartz-Schmidt KU, Szurman P, Spitzer MS & Aisenbrey S
    Comparative toxicity and proliferation testing of aflibercept, bevacizumab and ranibizumab on different ocular cells.
    Br J Ophthalmol. 2013 Jul;97(7):917-23. Epub 2013 May 17.
  8. Suesskind D, Schatz A, Schnichels S, Coupland SE, Lake SL, Wissinger B, Bartz-Schmidt KU & Henke-Fahle S
    GDF-15: a novel serum marker for metastases in uveal melanoma patients
    Graefes Arch Clin Exp Ophthalmol. 2012 Jun;250(6):887-95. Epub 2011 Sep 1.
  9. Gaub P, Joshi Y, Wuttke A, Naumann U, Schnichels S, Heiduschka P & Di Giovanni S
    The histone acetyltransferase p300 promotes intrinsic axonal regeneration.
    Brain. 2011 Jul;134(Pt 7):2134-48.
  10. Schnichels S, Heiduschka P & Julien S
    Different spatial and temporal protein expressions of RGMA and neogenin in the rat optic nerve after optic nerve crush with and without lens injury
    J Neurosci Res. 2011 Apr;89(4):490-505. Epub 2011 Feb 2.
  11. Heiduschka P, Julien S, Schüttauf F & Schnichels S
    Loss of retinal function in aged DBA/2J mice – new insights into retinal neurodegeneration
    Exp Eye Res. 2010 Nov;91(5):779-83. Epub 2010 Sep 9.
  12. Heiduschka P, Schnichels S, Fuhrmann N, Hofmeister S, Schraermeyer U, Wissinger B & Alavi MV
    Retinal ganglion cells are primarily affected in an animal model of OPA1 associated autosomal dominant optic atrophy.
    Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1424-31 2009 Oct 15.