Seeliger Lab

Ocular Neurodegeneration

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Susanne C. Beck

First nameSusanne
Present position and titleImaging Section Head, Dr. rer. nat.

Business address

Institute for Ophthalmic Research
Centre for Ophthalmology,
University of Tübingen
Elfriede-Aulhorn-Straße 7
72076 Tübingen

Phone: +49 (0)7071 29-87767
Fax: +49 (0)7071 29-4789
E-mail: su.beck[at]

Research Interests

  • In vivo imaging
  • Scanning-Laser-Ophthalmoscopy (SLO), Optical Coherence Tomography (OCT)
  • Animal models for hereditary retinal diseases
  • Retinal morphology and pathophysiology


  1. Weinl C, Riehle H, Park D, Stritt C, Beck S, et al. Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae. J Clin Invest. 2013;123(5):2193-206.
  2. Slezak M, Grosche A, Niemiec A, Tanimoto N, Pannicke T, Münch TA, Crocker B, Isope P, Härtig W, Beck SC, et al. Relevance of exocytotic glutamate release from retinal glia. Neuron. 2012;74(3):504-16.
  3. Koch S, Sothilingam V, Garcia Garrido M, Tanimoto N, Becirovic E, Koch F, Seide C, Beck SC, et al. Gene therapy restores vision and delays degeneration in the CNGB1(-/-) mouse model of retinitis pigmentosa. Hum Mol Genet. 2012;21(20):4486-96.
  4. Park B, Alves CH, Lundvig DM, Tanimoto N, Beck SC, et al. PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. J Neurosci. 2011;31(47):17230.
  5. Huber G, Imsand C, Heynen S., Feng Y, Mühlfriedel R, Hofmann W, Scheurlen U, Grimm C., Hammes H-P, Seeliger MW, Beck SC. Novel rodent models in macular research. PLoS One. 2010;5(10):e13403.
  6. Michalakis S, Mühlfriedel R, Tanimoto N, Krishnamoorthy V, Koch S, Fischer MD, Becirovic E, Bai L, Huber G, Beck SC, et al. Restoration of cone vision in the CNGA3-/- mouse model of congenital complete lack of cone photoreceptor function. Mol Ther. 2010;18(12):2057-63.
  7. Beck SC, Schaeferhoff K, Michalakis S, Fischer MD, Huber G, Rieger N, Riess O, Wissinger B, Biel M, Bonin M, Seeliger MW, Tanimoto N. In vivo analysis of cone survival in mice. Invest Ophthalmol Vis Sci. 2010;51(1):493-7.
  8. Feng Y, Vom Hagen F, Wang Y, Beck S, et al. The absence of angiopoietin-2 leads to abnormal vascular maturation and persistent proliferative retinopathy. Thromb Haemost. 2009;102(1):120-30.
  9. Joly S, Francke M, Ulbricht E, Beck S, et al. Cooperative phagocytes: resident microglia and bone marrow immigrants remove  dead photoreceptors in retinal lesions. Am J Pathol. 2009;174(6):2310-23.
  10. Dumelin CE, Trüssel S, Buller F, Trachsel E, Bootz F, Zhang Y, Mannocci L, Beck SC, et al. A portable albumin binder from a DNA-encoded chemical library. Angew Chem Int Ed Engl. 2008;47(17):3196-201.
  11. Aartsen WM, Kantardzhieva A, Klooster J, van Rossum AG, van de Pavert SA, Versteeg I, Cardozo BN, Tonagel F, Beck SC, et al. Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. Hum Mol Genet. 2006;15(8):1291-302.