Ueffing Lab

Molecular Biology of Retinal Degenerations

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Norbert Kinkl

First nameNorbert
Present position and titleScientific Project-  & Financial Management, Dr. rer. nat.

Business address

Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,

Phone: +49 (0)7071 29-84847
Fax: +49 (0)7071 29-5777
E-mail: norbert.kinkl[at]uni-tuebingen.de

Academic Education

Year Degree University Field of study
2001 Docteur de l’Université de Strasbourg I Université de Strasbourg I Neuroscience
1995 Diploma Technische Universität Darmstadt Biology

Professional Experience

Period Institution Position Discipline
2016 - current Institute for Ophthalmic Research, Eberhard-Karls Universität Tübingen Scientific Project- & Financial Management
2010 - 2015 Institute for Ophthalmic Research, Eberhard-Karls Universität Tübingen Group Leader Neuroscience, Proteomics
2002-2009 Department of Protein Science, Helmholtz-Zentrum München Postdoc Neuroscience
1996-2001 Laboratoire de Physiopathologie Rétinienne, INSERM Université Louis Pasteur EMI 9918, Strasbourg PhD student Retinal Degeneration and Neuroprotection
1994-1995 Institute for Zoology, Technische Universität Darmstadt Dimploma student Expression of Cholinesterases in the Chick Retina


2002Retinitis Pigmentosa Award from the Pro Retina Germany and Retina Suisse

Additional information

2010-2013Assistent Coordinator BMBF Research Cluster SYSTEC - Dynamo
2006-2009Assistent Coordinator BMBF Research Cluster - QuantPro

Memberships and Functions in Scientific Societies

  • Pro Retina Germay


  1. Vogt A, Fuerholzner B, Kinkl N, Boldt, K, Ueffing M
    Isotope Coded Protein Labeling Coupled Immunoprecipitation (ICPL-IP): A Novel Approach for Quantitative Protein Complex Analysis From Native Tissue. (2013) Mol Cell Prot, 12(5):1395-406. doi: 10.1074/mcp.O112.023648. Epub 2012 Dec 26.
  2. Texier Y, Kinkl N, Boldt K, Ueffing M
    From quantitative protein complex analysis to disease mechanism. (2012) Vis Res, Dec 15;75:108-11. doi: 10.1016/j.visres.2012.08.016. Epub 2012 Sep 23
  3. Kiel C, Vogt A, Campagna A, Chatr-Aryamontri A, Swiatek-de Lange M, Beer M, Bolz S, Mack AF, Kinkl N, Cesareni G, Serrano L, Ueffing M
    Structural and functional protein network analyses predict novel signaling functions for rhodopsin (2011). Mol Systems Biol, Nov 22; 7:551. doi: 10.1038/msb.2011.83.
  4. Boldt K, Mans D, Won J, van Reeuwijk J, Vogt A, Kinkl N, Letteboer S, Hicks W, Hurd R, Naggert J, Texier Y, den Hollander A, Koenekoop R, Bennett J, Cremers F, Gloeckner CJ, Nishina P, Roepman R, Ueffing M.
    Disruption of intraflagellar transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice. (2011) J Clin Invest 121(6):2169-80. doi: 10.1172/JCI45627. Epub 2011 May 23.
  5. Meixner A, Boldt K, Van Troys M, Askenazi M, Gloeckner CJ, Bauer M, Marto JA, Ampe C, Kinkl N, Ueffing M.
    A QUICK screen for Lrrk2 interaction partners – leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. (2011) Mol Cell Prot 10(1):M110.001172. Epub 2010 Sep 27.
  6. Braun RJ, Kinkl N, Beer M, Ueffing M.
    Two-dimensional electrophoresis of membrane proteins. (2007) Anal Bioanal Chem 389:1033-45 (Review)
  7. Gloeckner CJ, Kinkl N, Schumacher A, Braun RJ, O’Neill E, Meitinger T, Kolch W, Prokisch H, Ueffing M.
    The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity. (2006) Hum Mol Genet 15: 223-232.
  8. Traverso V, Kinkl N, Grimm L, Sahel J, Hicks D.
    Basic Fibroblast and Epidermal Growth Factors Stimulate Survival in Adult Porcine Photoreceptor Cell Cultures. (2003) Invest Ophthalmol Vis Sci 44: 4550-4558.
  9. Kinkl N, Ruiz J, Vecino E, Frasson M, Sahel J, Hicks D.
    Possible involvement of a fibroblast growth factor 9 (FGF9)–FGF receptor-3-mediated pathway in adult pig retinal ganglion cells in vitro. (2003) Mol Cell Neurosci 23:39-53.
  10. Kinkl N, Hageman GS, Sahel J, Hicks D.
    Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina. (2002) Mol Vis 8:149-160.
  11. Kinkl N, Sahel JA, Hicks D.
    Alternate FGF2-ERK1/2 signaling pathways in retinal photoreceptor and glial cells in vitro. (2001) J Biol Chem. 276:43871-43878.
  12. Fontaine V, Kinkl N, Sahel J, Dreyfus H, Hicks D.
    Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2. (1998) J Neurosci 18:9662-9672.