Ueffing Lab

Molecular Biology of Retinal Degenerations

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Age-relate macular degeneration (AMD)

AMD is the most frequent cause of vision loss in Europe. AMD destroys the cone photoreceptors of the central part of the retina needed for reading and driving. Our aim is to moving the understanding of AMD pathogenesis forward. We pursue two approaches. The first approach is the large collaborative project EYE-RISK. The EYE-RISK consortium comprises a wide range of experts that conduct joint analyses of AMD risks and pathways. EYE-RISK aims to build a model of risks and molecular drivers that enables patients, clinicians, and pharmaceutical industry to prevent, predict and treat AMD. The second approach is to elucidate the role of the locus 10q26 in AMD.

Related Projects

  • EYE-RISK
    Exploring the combined role of genetic and non-genetic factors for developing Age-Related Macular Degeneration: A systems level analysis of disease subgroups, risk factors, and pathways
  • The 10q26 locus in AMD