Zrenner Lab

Experimental Retinal Prothetics Group

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Zohreh Hosseinzadeh

SurnameHosseinzadeh
First nameZohre
NationalityIranian
Present position and titlePhD, Postdoc

Business address

Experimental Retinal Prothetics Group
Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Straße 7
72076 Tübingen
Germany

Phone: +49 (0)7071 29-87785
Fax: +49 (0)7071 29-4472
E-mail: zohreh.hosseinzadeh[at]uni-tuebingen.de

Academic Education

Year Degree University Field of study
2014 Ph.D. University of Tübingen Biology
2007 M.Sc Shahid Chamran University Biology
2002 B.Sc Shahid Chamran University General Biology

Professional Experience

Period Institution Position Discipline
2015-now Eberhard-Karls-University Tuebingen, Germany BMBF Postdoc Retinal Prosthetics
2014-2015 Eberhard-Karls-University Tuebingen, Germany Postdoc Electrophysiology
2007-2009 Lecturer at Payame Noor University Shiraz and stahban/ Iran

Research Area

  • Pathophysiology of Vision Lab, Experimental Retinal Prosthetics Group
  • Built an in vitro experimental system combining an actual retinal implant with patch clamp electrophysiology and histological cell type classification.
  • selectively stimulate the retina

Awards / Scholarships

2016Tistou und Charlotte Kerstan Stiftung award
2016Cambridge bursary to attend the eye symposium
2013Travel award, MipTec congress, Basel, Schweiz
2009Award for study abroad
2007Elected as the fourth honor M.Sc. student
2001Elected as the third honor B.Sc. student

Additional information

Referee:

  • cellular physiology and biochemistry Journal
  • Kidney and blood pressure journal

Publications

  1. Fezai M, Ahmed M, Hosseinzadeh Z, Lang F. Up-Regulation of the Large-Conductance Ca2+-Activated K+ Channel by Glycogen Synthase Kinase GSK3β. Cell Physiol Biochem. 2016 Aug 19;39(3):1031-1039.
  2. Almilaji A, Yan J, Hosseinzadeh Z, Schmid E, Gawaz M, Lang F. Up-Regulation of Na+/Ca2+ Exchange in Megakaryocytes Following TGFβ1 Treatment. Cell Physiol Biochem. 2016;39(2):693-9. doi: 10.1159/000445660. Epub 2016 Jul 21.
  3. Ghashghaeinia M, Giustarini D, Koralkova P, Köberle M, Alzoubi K, Bissinger R, Hosseinzadeh Z, Dreischer P, Bernhardt I, Lang F, Toulany M, Wieder T, Mojzikova R, Rossi R, Mrowietz U. Pharmacological targeting of glucose-6-phosphate dehydrogenase in human erythrocytes by Bay 11-7082, parthenolide and dimethyl fumarate.
  4. Yan J, Zhang B, Hosseinzadeh Z, Lang F.Down-Regulation of Store-Operated Ca2+ Entry and Na+ Ca2+ Exchange in MCF-7 Breast Cancer Cells by Pharmacological JAK3 Inhibition. Cell Physiol Biochem. 2016;38(4):1643-51.
  5. Yan J, Zhang B, Hosseinzadeh Z, Lang F.Down-Regulation of Store-Operated Ca2+ Entry and Na+ Ca2+ Exchange in MCF-7 Breast Cancer Cells by Pharmacological JAK3 Inhibition.Cell Physiol Biochem. 2016;38(4):1643-51.
  6. Yan J, Zhang B, Hosseinzadeh Z, Lang F.Down-Regulation of Store-Operated Ca2+ Entry and Na+ Ca2+ Exchange in MCF-7 Breast Cancer Cells by Pharmacological JAK3 Inhibition. Cell Physiol Biochem. 2016;38(4):1643-51.
  7. Yan J, Hosseinzadeh Z, Zhang B, Froeschl M, Schulze-Osthoff K, Stournaras C, Lang F. Decrease of Store-Operated Ca2+ Entry and Increase of Na+/Ca2+ Exchange by Pharmacological JAK2 Inhibition. Cell Physiol Biochem. 2016;38(2):683-95.
  8. Ahmed M, Fezai M, Uzcategui NL, Hosseinzadeh Z, Lang F.SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5). Cell Physiol Biochem. 2016;38(1):359-67.
  9. Fezai M, Ahmed M, Hosseinzadeh Z, Elvira B, Lang F. SPAK and OSR1 Sensitive Kir2.1 K+ Channels. Neurosignals. 2015;23(1):20-33.
  10. Pelzl L, Hosseinzadeh Z, Alzoubi K, Al-Maghout T, Schmidt S, Stournaras C, Lang F.Impact of Na+/Ca2+ Exchangers on Therapy Resistance of Ovary Carcinoma Cells. Cell Physiol Biochem. 2015;37(5):1857-68
  11. Ahmed M, Honisch S, Pelzl L, Fezai M, Hosseinzadeh Z, Bock CT, Kandolf R, Lang F. Up-regulation of epithelial Na(+) channel ENaC by human parvovirus B19 capsid protein VP1. Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):179-84
  12. Fezai M, Elvira B, Warsi J, Ben-Attia M, Hosseinzadeh Z, Lang F. Up-Regulation of Intestinal Phosphate Transporter NaPi-IIb (SLC34A2) by the Kinases SPAK and OSR1. Kidney Blood Press Res. 2015;40(6):555-64.
  13. Warsi J, Singh Y, Elvira B, Hosseinzadeh Z, Lang F. Regulation of Large Conductance Voltage-and Ca2+-Activated K+ Channels by the Janus Kinase JAK3. Cell Physiol Biochem. 2015;37(1):297-305.
  14. Yan J, Schmid E, Hosseinzadeh Z, Honisch S, Shumilina E, Fuchs J, Lang F. Impact of Janus Kinase 3 on Cellular Ca Release, Store Operated Ca(2+) Entry and Na(+)/Ca(2+) Exchanger Activity in Dendritic Cells. Cell Physiol Biochem. 2015;36(6):2287-98.
  15. Ahmed M, Salker MS, Elvira B, Umbach AT, Fakhri H, Saeed AM, Shumilina E, Hosseinzadeh Z, Lang F. SPAK Sensitive Regulation of the Epithelial Na Channel ENaC. Kidney Blood Press Res. 2015;40(4):335-43.
  16. Warsi J, Elvira B, Bissinger R, Hosseinzadeh Z, Lang F. Regulation of Voltage-Gated K(+) Channel Kv1.5 by the Janus Kinase JAK3. J Membr Biol. 2015 Jun 23.
  17. Warsi J, Hosseinzadeh Z, Elvira B, Pelzl L, Shumilina E, Zhang DE, Lang KS, Lang PA, Lang F. USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2. PLoS One. 2015 Jun 5;10(6):e0129365.
  18. Hosseinzadeh Z, Honisch S, Schmid E, Jilani K, Szteyn K, Bhavsar S, Singh Y, Palmada M, Umbach AT, Shumilina E, Lang F. The Role of Janus Kinase 3 in the Regulation of Na⁺/K⁺ ATPase under Energy Depletion. Cell Physiol Biochem. 2015;36(2):727-40.
  19. Schmid E, Yan J, Hosseinzadeh Z, Almilaji A, Shumilina E, Kuro-o M, Borst O, Gawaz M, Lang F. Up-regulation of megakaryocytic Na(+)/Ca(2+) exchange in klotho-deficient mice. Biochem Biophys Res Commun. 2015 May 1;460(2):177-82.
  20. Hosseinzadeh Z, Warsi J, Elvira B, Almilaji A, Shumilina E, Lang F.Up-regulation of Kv1.3 channels by janus kinase 2. J Membr Biol. 2015 Apr;248(2):309-17.
  21. Almilaji A, Honisch S, Liu G, Elvira B, Ajay SS, Hosseinzadeh Z, Ahmed M, Munoz C, Sopjani M, Lang F. Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein. Kidney Blood Press Res. 2014;39(6):609-22.
  22. Warsi J, Dong L, Elvira B, Salker MS, Shumilina E, Hosseinzadeh Z, Lang F. SPAK Dependent Regulation of Peptide Transporters PEPT1 and PEPT2. Kidney Blood Press Res. 2014;39(4):388-98.
  23. Warsi J, Hosseinzadeh Z, Elvira B, Bissinger R, Shumilina E, Lang F. Regulation of ClC-2 Activity by SPAK and OSR1. Kidney Blood Press Res. 2014;39(4):378-87.
  24. Hosseinzadeh Z, Schmid E, Shumilina E, Laufer S, Borst O, Gawaz M, Lang F.Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes. Biochem Biophys Res Commun. 2014 Sep 26;452(3):537-41.
  25. Warsi J, Luo D, Elvira B, Jilani K, Shumilina E, Hosseinzadeh Z, Lang F. Upregulation of Excitatory Amino Acid Transporters by Coexpression of Janus Kinase 3. J Membr Biol. 2014 Jun 14
  26. Hosseinzadeh Z, Almilaji A, Honisch S, Pakladok T, Liu G, Bhavsar SK, Ruth P, Shumilina E, Lang F. Upregulation of the large conductance voltage- and Ca2+-activated K+ channels by Janus kinase 2. Am J Physiol Cell Physiol. 2014 Jun 1;306(11):C1041-9.
  27. Warsi J, Elvira B, Hosseinzadeh Z, Shumilina E, Lang F.Downregulation of Chloride Channel ClC-2 by Janus Kinase 3.J Membr Biol. 2014 Mar 11
  28. Hosseinzadeh Z, Luo D, Sopjani M, Bhavsar SK, Lang F.Down-Regulation of the Epithelial Na(+) Channel ENaC by Janus kinase 2. J Membr Biol. 2014 Apr;247(4):331-
  29. Pakladok T, Hosseinzadeh Z, Almilaji A, Lebedeva A, Shumilina E, Alesutan I, Lang F. Up-regulation of hERG K+ channels by B-RAF. PLoS One. 2014 Jan 27;9(1):e87457.
  30. Dërmaku-Sopjani M, Almilaji A, Pakladok T, Munoz C, Hosseinzadeh Z, Blecua M, Sopjani M, Lang F. Down-regulation of the Na-coupled phosphate transporter NaPi-IIa by AMP-activated protein kinase. Kidney Blood Press Res. 2013;37(6):547-56.
  31. Pasham V, Rotte A, Mia S, Alesutan I, Chatterjee S, Hosseinzadeh Z, Bhandaru M, Noegel AA, Lang F. Annexin 7 in the regulation of gastric acid secretion. Cell Physiol Biochem. 2013;32(6):1643-54.
  32. Bhavsar SK, Hosseinzadeh Z, Brenner D, Honisch S, Jilani K, Liu G, Szteyn K, Sopjani M, Mak TW, Shumilina E, Lang F. Energy-sensitive regulation of Na+/K+-ATPase by Janus kinase 2. Am J Physiol Cell Physiol. 2014 Feb;306(4):C374-84.
  33. Umbach AT, Luo D, Bhavsar SK, Hosseinzadeh Z, Lang F. Intestinal Na+ loss and volume depletion in JAK3-deficient mice. Kidney Blood Press Res. 2013;37(4-5):514-20.
  34. Pakladok T, Hosseinzadeh Z, Lebedeva A, Alesutan I, Lang F. Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF. J Membr Biol. 2014 Feb;247(2):137-45.
  35. Bhavsar SK, Schmidt S, Bobbala D, Nurbaeva MK, Hosseinzadeh Z, Merches K, Fajol A, Wilmes J, Lang F. AMPKα1-sensitivity of Orai1 and Ca(2+) entry in T - lymphocytes. Cell Physiol Biochem. 2013;32(3):687-98.
  36. Almilaji A, Munoz C, Hosseinzadeh Z, Lang F. Upregulation of Na+,Cl(-)-coupled betaine/γ-amino-butyric acid transporter BGT1 by Tau tubulin kinase 2. Cell Physiol Biochem. 2013;32(2):334-43.
  37. Warsi J, Hosseinzadeh Z, Dong L, Pakladok T, Umbach AT, Bhavsar SK, Shumilina E, Lang F. Effect of Janus kinase 3 on the peptide transporters PEPT1 and PEPT2. J Membr Biol. 2013 Dec;246(12):885-92.
  38. Hosseinzadeh Z, Dong L, Bhavsar SK, Warsi J, Almilaji A, Lang F. Upregulation of peptide transporters PEPT1 and PEPT2 by Janus kinase JAK2. Cell Physiol Biochem. 2013;31(4-5):673-82.
  39. Hosseinzadeh Z, Sopjani M, Pakladok T, Bhavsar SK, Lang F. Downregulation of KCNQ4 by Janus kinase 2. J Membr Biol. 2013 Apr;246(4):335-41.
  40. Shojaiefard M, Hosseinzadeh Z, Pakladok T, Bhavsar SK, Lang F. Stimulation of Na+ coupled phosphate transporter NaPiIIa by janus kinase JAK2. Biochem Biophys Res Commun. 2013 Feb 8;431(2):186-91.
  41. Hosseinzadeh Z, Bhavsar SK, Lang F.Down-regulation of the myoinositol transporter SMIT by JAK2. Cell Physiol Biochem. 2012;30(6):1473-80.
  42. Pakladok T, Hosseinzadeh Z, Alesutan I, Lang F. Stimulation of the Na(+)-coupled glucose transporter SGLT1 by B-RAF. Biochem Biophys Res Commun. 2012 Nov 2;427(4):689-93.
  43. Hosseinzadeh Z, Bhavsar SK, Lang F. Downregulation of ClC-2 by JAK2. Cell Physiol Biochem. 2012;29(5-6):737-42.
  44. Shojaiefard M, Hosseinzadeh Z, Bhavsar SK, Lang F. Downregulation of the creatine transporter SLC6A8 by JAK2. J Membr Biol. 2012 Mar;245(3):157-63.
  45. Hosseinzadeh Z, Shojaiefard M, Bhavsar SK, Lang F. Up-regulation of the betaine/GABA transporter BGT1 by JAK2. Biochem Biophys Res Commun. 2012 Mar 30;420(1):172-7.
  46. Hosseinzadeh Z, Bhavsar SK, Sopjani M, Alesutan I, Saxena A, Dërmaku-Sopjani M, Lang F. Regulation of the glutamate transporters by JAK2. Cell Physiol Biochem. 2011;28(4):693-702.
  47. Bhavsar SK, Hosseinzadeh Z, Merches K, Gu S, Bröer S, Lang F.Stimulation of the amino acid transporter SLC6A19 by JAK2. Biochem Biophys Res Commun. 2011 Oct 28;414(3):456-61.
  48. Hosseinzadeh Z, Bhavsar SK, Shojaiefard M, Saxena A, Merches K, Sopjani M, Alesutan I, Lang F. Stimulation of the glucose carrier SGLT1 by JAK2. Biochem Biophys Res Commun. 2011 May 6;408(2):208-13.
  49. Moazedi AA, Hossienzadeh Z, Chinpardaz R. The effects of coadministration palmitic acid and oleic acid (omega 9) on spatial learning and motor activity in adult male rat. Pak J Biol Sci. 2007 Oct 15;10(20):3650-5.
  50. Hosseinzadeh Z, Moazedi AA, Chinipardaz R The effect of palmitic acid on spatial learning and extinction in adult male rat. Pak J Biol Sci. 2007 Aug 15;10(16):2653-8.