Zrenner Lab

Pathophysiology of Vision

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2021

  1. O627 Kohl S, Llavona P, Sauer A, Reuter P, Weisschuh N, Kempf M, Dehmelt FA, Arrenberg AB, Sliesoraityte I, Zrenner E, van Schooneveld MJ, Rudolph G, Kühlewein L, Wissinger B; A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect: Hum Mol Genet. 2021 Apr 22:ddab117. doi: 10.1093/hmg/ddab117. Online ahead of print
  2. O626 Nassisi M, Smirnov V, Hernandez CS, Mohand-Saïd S, Condroyer C, Antonio A, Kühlewein L, Kempf M, Kohl S, Wissinger B, Nasser F, Ragi SD, Wang NK, Sparrow JR, Greenstein V, Michalakis S, Mahroo O, Ba-Abbad R, Michaelides M, Webster AR, Esposti SD, Saffren B, Capasso J, Levin A, Hauswirth WW, Dhaenens CM, Defoort-Dhellemmes S, Tsang SH, Zrenner E, Sahel JA, Petersen-Jones S, Zeitz C, Audo I; CNGB1-related rod-cone dystrophy: a mutation review and update: Hum Mutat. 2021 Apr 12. doi: 10.1002/humu.24205. Online ahead of print
  3. O625 Kuehlewein L, Zobor D, Stingl K, Kempf M, Nasser F, Bernd A, Biskup S, Cremers FPM, Khan MI, Mazzola P, Schäferhoff K, Heinrich T, Haack TB, Wissinger B, Zrenner E, Weisschuh N, Kohl S; Clinical Phenotype of PDE6B-Associated Retinitis Pigmentosa. Int J Mol Sci. 2021 Feb 27;22(5):2374. doi: 10.3390/ijms22052374
  4. O624 Georgiou M, Fujinami K, Vincent A, Nasser F, Khateb S, Vargas ME, Thiadens AAHJ, de Carvalho ER, Nguyen XT, De Guimarães TAC, Robson AG, Mahroo OA, Pontikos N, Arno G, Fujinami-Yokokawa Y, Leo SM, Liu X, Tsunoda K, Hayashi T, Jimenez-Rolando B, Martin-Merida MI, Avila-Fernandez A, Carreño E, Garcia-Sandoval B, Carmen A, Sharon D, Kohl S, Huckfeldt RM, Boon CJF, Banin E, Pennesi ME, Wissinger B, Webster AR, Héon E, Khan AO, Zrenner E, Michaelides M.; KCNV2-associated Retinopathy: Detailed Retinal Phenotype and Structural Endpoints - KCNV2 Study Group Report 2. Am J Ophthalmol. 2021 Mar 15:S0002-9394(21)00117-3. doi: 10.1016/j.ajo.2021.03.004. Online ahead of print
  5. O623 Stingl K, Kempf M, Bartz-Schmidt KU, Dimopoulos S, Reichel F, Jung R, Kelbsch C, Kohl S, Kortüm FC, Nasser F, Peters T, Wilhelm B, Wissinger B, Wozar F, Zrenner E, Fischer MD, Stingl K: Spatial and temporal resolution of the photoreceptors rescue dynamics after treatment with voretigene neparvovec; Br J Ophthalmol. 2021 Jan 20:bjophthalmol-2020-318286. doi: 10.1136/bjophthalmol-2020-318286. Online ahead of print.

2020

  1. O622 Georgiou M, Robson AG, Fujinami K, Leo SM, Vincent A, Nasser F, Cabral De Guimarães TA, Khateb S, Pontikos N, Fujinami-Yokokawa Y, Liu X, Tsunoda K, Hayashi T, Vargas ME, Thiadens AAHJ, de Carvalho ER, Nguyen XT, Arno G, Mahroo OA, Martin-Merida MI, Jimenez-Rolando B, Gordo G, Carreño E, Carmen A, Sharon D, Kohl S, Huckfeldt RM, Wissinger B, Boon CJF, Banin E, Pennesi ME, Khan AO, Webster AR, Zrenner E, Héon E, Michaelides M: KCNV2-associated Retinopathy: Genetics, Electrophysiology and Clinical Course - KCNV2 Study Group Report 1; Am J Ophthalmol. 2020 Dec 10:S0002-9394(20)30656-5. doi: 10.1016/j.ajo.2020.11.022. Online ahead of print.
  2. O621 Samardzija, M, Corna, A, Gomez-Sintes, R, Jarboui MA, Armento A, Roger JE, Petridou E, Haq W, Paquet-Durand F, Zrenner E, de la Villa P, Zeck G, Grimm C, Boya P, Ueffing M, Trifunović D: HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice. Cell Death Differ; Published: 06 November 2020 doi.org/10.1038.
  3. O620 Stingl K, Stingl K, Nowomiejska K, Kuehlewein L, Kohl S, Kempf M, Strasser T, Jung R, Wilhelm B, Peters T, Kelbsch C, Bartz-Schmidt KU, Langrova H, Zrenner E. Clinical protocols for the evaluation of rod function. Ophthalmologica. 2020 Aug 17. doi: 10.1159/000510888. Online ahead of print.
  4. O619 Kuehlewein L, Zobor D, Andreasson SO, Ayuso C, Banfi S, Bocquet B, Bernd AS, Biskup S, Boon CJF, Downes SM, Fischer MD, Holz FG, Kellner U, Leroy BP, Meunier I, Nasser F, Rosenberg T, Rudolph G, Stingl K, Thiadens AAHJ, Wilhelm B, Wissinger B, Zrenner E, Kohl S, Weisschuh N; RD-CURE Consortium: Clinical Phenotype and Course of PDE6A-Associated Retinitis Pigmentosa Disease, Characterized in Preparation for a Gene Supplementation Trial. JAMA Ophthalmol. 2020 Oct 15:e204206. doi: 10.1001/jamaophthalmol.2020.4206. Online ahead of print. PMID: 33057649
  5. O618 Zrenner E, Holder GE, Schiefer U, Wild JM. Quality control procedures and baseline values for electroretinography, perimetry, color vision, and visual acuity in an international multicenter study: observations from a safety trial in chronic stable angina pectoris. Transl Vis Sci Technol. 2020 Jul 28;9(8):38. doi: 10.1167/tvst.9.8.38. eCollection 2020 Jul.
  6. O617 Schönbach EM, Strauss RW, Muñoz B, Wolfson Y, Ibrahim MA, Birch DG, Zrenner E, Sunness JS, Ip MS, Sadda SR, West SK, Scholl HPN; ProgStar Study Group. Longitudinal microperimetric changes of macular sensitivity in Stargardt disease after 12 months: ProgStar Report No. 13. JAMA Ophthalmol. 2020 May 28;138(7):1-8. doi: 10.1001/jamaophthalmol.2020.1735. Online ahead of print.
  7. O616 Lauren N. Ayton, Joseph F. Rizzo, Ian L. Bailey, August Colenbrander, Gislin Dagnelie, Duane R. Geruschat, Philip C. Hessburg, Chris D. McCarthy, Matthew A. Petoe, Gary S. Rubin, Philip R. Troyk: Harmonization of outcomes and vision endpoints in vision restoration trials: Recommendations from the International HOVER Taskforce. (P44: Dagnelie G (chair), Kusnyerik A, Mann C, Zrenner E, Fernandez E, Lane F, Rubin G, Stingl K, Merabet L, Finger R, Fujikado T, and J. Vernon Odom J Patient-Reported Outcomes); Translational Vision Science & Technology, July 2020, DOI 10.1167/tvst.9.8.25.
  8. O615 Straßer T, Kurtenbach A, Langrová H, Kuehlewein L, Zrenner E: The perception threshold of the panda illusion, a particular form of 2D pulse-width-modulated halftone, correlates with visual acuity. Sci Rep. 2020 Aug 4;10(1):13095. doi: 10.1038/s41598-020-69952-6.
  9. O614 Weisschuh N, Obermaier CD, Battke F, Bernd A, Kuehlewein L, Nasser F, Zobor D, Zrenner E, Weber E, Wissinger B, Biskup S, Stingl K, Kohl S: Genetic architecture of inherited retinal degeneration in Germany: A large cohort study from a single diagnostic center over a 9-year period. Hum Mutat. 2020 Jun 12. doi: 10.1002/humu.24064. Online ahead of print.
  10. O613 Straßer T, Wagner S, Zrenner E: Review of the application of the open-source software CilOCT for semi-automatic segmentation and analysis of the ciliary muscle in OCT images. PLoS One. 2020 Jun 9;15(6):e0234330. doi: 10.1371/journal.pone.0234330. eCollection 2020.
  11. O612 Hosseinzadeh Z, Hauser S, Singh Y, Pelzl L, Schuster S, Sharma Y, Höflinger P, Zacharopoulou N, Stournaras C, Rathbun DL, Zrenner E, Schöls L, Lang F. Decreased Na+/K+ ATPase expression and depolarized cell membrane in neurons differentiated from Chorea-Acanthocytosis patients. Sci Rep. 2020 May 21;10(1):8391. doi: 10.1038/s41598-020-64845-0.
  12. O611 Schönbach EM, Strauss RW, Ahmed MI, Janes JL, Cideciyan AV, Birch DG, Sunness JS, Zrenner E, Ip MS, Kong X, Sadda SR, Scholl HPN, for the ProgStar study group, The effect of attention on fixation stability during dynamic fixation testing in Stargardt disease, American Journal of Ophthalmology (2020), doi: doi.org/10.1016/j.ajo.2020.05.002.
  13. O610 Sekhar S, Ramesh P, Bassetto G, Zrenner E, Macke JH, Rathbun DL: Characterizing retinal ganglion cell responses to electrical stimulation using generalized linear models. Frontiers in Neuroscience 2020, V 14 P 378 doi:10.3389/fnins.2020.00378, ISSN 1662-453X
  14. O609 Fischer MD, Michalakis S, Wilhelm B, Zobor D, Muehlfriedel R, Kohl S, Weisschuh N, Ochakovski GA, Klein R, Schoen C, Sothilingam V, Garcia-Garrido M, Kuehlewein L, Kahle N, Werner A, Dauletbekov D, Paquet-Durand F, Tsang S, Martus P, Peters T, Seeliger M, Bartz-Schmidt KU, Ueffing M, Zrenner E, Biel M, Wissinger B: Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial. JAMA Ophthalmol. 2020 Apr 30. doi: 10.1001/jamaophthalmol.2020.1032. [Epub ahead of print]
  15. O608 Cehajic Kapetanovic J, Troelenberg N, Edwards TL, Xue K, Ramsden JD, Stett A, Zrenner E, MacLaren RE: Highest reported visual acuity after electronic retinal implantation. Acta Ophthalmol. 2020 Apr 28. doi: 10.1111/aos.14443. [Epub ahead of print]
  16. O607 Faber H, Besch D, Bartz-Schmidt KU, Eisenstein H, Roider J, Sachs H, Gekeler F, Zrenner E, Stingl K: Restriction of eye motility in patients with RETINA IMPLANT Alpha AMS. Acta Ophthalmol. 2020 Apr 17. doi: 10.1111/aos.14435. [Epub ahead of print]
  17. O606 Schönbach EM, Strauss RW, Ibrahim MA, Janes JL, Birch DG, Cideciyan AV, Sunness JS, Muñoz B, Ip MS, Sadda SR, Scholl HPN; ProgStar study group: Faster sensitivity loss around dense scotomas than for overall macular sensitivity in Stargardt disease: ProgStar Report No. 14. Am J Ophthalmol. 2020 Mar 25. pii: S0002-9394(20)30120-3. doi: 10.1016/j.ajo.2020.03.020. [Epub ahead of print]
  18. O605 Jolly JK, Wagner SK, Martus P, MacLaren RE, Wilhelm B, Webster AR, Downes SM, Charbel Issa P, Kellner U, Jägle H, Rüther K, Bertelsen M, Bragadóttir R, Prener Holtan J, van den Born I, Sodi A, Virgili G, Gosheva M, Pach J, Zündorf I, Zrenner E, Gekeler F: Transcorneal electrical stimulation for the treatment of retinitis pigmentosa - a multicenter safety study of the OkuStim® System (TESOLA-study). Ophthalmic Res. 2019 Nov 26. doi: 10.1159/000505001. [Epub ahead of print]
  19. O604 Nasser F, Kurtenbach A, Biskup S, Weidensee S, Kohl S, Zrenner E: Ophthalmic features of retinitis pigmentosa in Cohen syndrome caused by pathogenic variants in the VPS13B gene. Acta Ophthalmol. 2019 Oct 3. doi: 10.1111/aos.14255. [Epub ahead of print]
  20. O603 Fischer MD, Ochakovski GA, Beier B, Seitz IP, Vaheb Y, Kortuem C, Reichel FFL, Kuehlewein L, Kahle NA, Peters T, Girach A, Zrenner E, Ueffing M, MacLaren RE, Bartz-Schmidt KU, Wilhelm B: Efficacy and safety of retinal gene therapy using adeno-associated virus vector for patients with choroideremia: a randomized clinical trial. JAMA Ophthalmol. 2019 Aug 29. doi: 10.1001/jamaophthalmol.2019.3278. [Epub ahead of print]
  21. O602 Faber H, Bartz-Schmidt KU, Stett A, Zrenner E, Stingl K.[Electronic Retina Implants - an abandoned dream?] German. Klin Monbl Augenheilkd. 2020 Mar; 237(3):288-293. doi: 10.1055/a-1021-5040. Epub 2020 Mar 17
  22. O601 Nasser F, Kempf M, Kurtenbach A, Stöhr H, Weber BHF, Neuhaus C, Rating P, Zrenner E: Correlating adaptive optics images to clinical findings in juvenile macular dystrophy with hypotrichosis in siblings with homozygous CDH3 pathogenic variation. Ophthalmic Res. 2020; 63(2):141-151. doi: 10.1159/000504757. Epub 2020 Jan 10.

2019

  1. O600 Stingl KT, Kuehlewein L, Weisschuh N, Biskup S, Cremers FPM, Khan MI, Kelbsch C, Peters T, Ueffing M, Wilhelm B, Zrenner E, Stingl K: Chromatic full-field stimulus threshold and pupillography as functional markers for late-stage, early-onset retinitis pigmentosa caused by CRB1 mutations. Transl Vis Sci Technol. 2019 Dec 20; (6):45. doi: 10.1167/tvst.8.6.45. eCollection 2019 Nov.
  2. O599 Feldhaus B, Weisschuh N, Nasser F, den Hollander AI, Cremers FPM, Zrenner E, Kohl S, Zobor D: CEP290 mutation spectrum and delineation of the associated phenotype in a large German cohort: a monocentric study. Am J Ophthalmol. 2020 Mar; 211:142-150. doi: 10.1016/j.ajo.2019.11.012. Epub 2019 Nov 14.
  3. O598 Straßer T, Kramer S, Kempf M, Peters T, Kurtenbach A, Zrenner E: Visual evoked potentials used to evaluate a commercially available superabsorbent polymer as a cheap and efficient material for preparation-free electrodes for recording electrical potentials of the human visual cortex. Sensors (Basel). 2019 Nov 9; 19(22). pii: E4890. doi: 10.3390/s19224890.
  4. O597 Fiedorowicz M, Choragiewicz T, Thaler S, Schuettauf F, Nowakowska D, Wojtunik K, Reibaldi M, Avitabile T, Kocki T, Turski W. A., Kaminska A, Grieb P, Zrenner E, Rejdak R Toro M.D: Tryptophan and kynurenine pathway metabolites in animal models of retinal and optic nerve damage: different dynamics of changes. Front Physiol. 2019 Oct 1; 10:1254. doi: 10.3389/fphys.2019.01254. eCollection 2019.
  5. O596 Wagner S, Zrenner E, Strasser T: Emmetropes and myopes differ little in their accommodation dynamics but strongly in their ciliary muscle morphology. Vision Res. 2019 Oct; 163:42-51. doi: 10.1016/j.visres.2019.08.002. Epub 2019 Aug 28.
  6. O595 Strauss RW, Kong X, Ho A, Jha A, West S, Ip M, Bernstein PS, Birch DG, Cideciyan AV, Michaelides M, Sahel JA, Sunness JS, Traboulsi EI, Zrenner E, Pitetta S, Jenkins D, Hariri AH, Sadda S, Scholl HPN, ProgStar Study Group, Progression of Stargardt disease as determined by fundus autofluorescence over a 12-month period: ProgStar Report No. 11. JAMA Ophthalmol. 2019; 137(10):1134-1145. doi:10.1001/jamaophthalmol.2019.2885. Epub 2019 Aug 1
  7. O594 Wagner S, Schaeffel F, Zrenner E, Straßer T: Response to comment on 'Prolonged nearwork affects the ciliary muscle morphology' by Schachar & Schachar. Exp Eye Res. 2019 Oct; 187:107786. doi: 10.1016/j.exer.2019.107786. Epub 2019 Sep 6.
  8. O593 Wagner S, Schaeffel F, Zrenner E, Straßer T: Prolonged nearwork affects the ciliary muscle morphology. Exp Eye Res. 2019 Sep; 186:107741. doi: 10.1016/j.exer.2019.107741. Epub 2019 Jul 20.
  9. O592 Stingl K, Kurtenbach A, Hahn G, Kernstock C, Hipp S, Zobor D, Kohl S, Bonnet C, Mohand-Saïd S, Audo I, Fakin A, Hawlina M, Testa F, Simonelli F, Petit C, Sahel JA, Zrenner E: Full-field electroretinography, visual acuity and visual fields in usher syndrome: a multicentre european study. Doc Ophthalmol. 2019 Oct; 139(2):151-160. doi: 10.1007/s10633-019-09704-8. Epub 2019 Jul 2
  10. O591 Nasser F, Kohl S, Kuehlewein L, Wissinger B, Obermaier CD, Kurtenbach A, Zrenner E: A case of X-linked retinoschisis with atypical fundus appearance. Doc Ophthalmol. 2019 Aug; 139(1):75-81. doi: 10.1007/s10633-019-09698-3. Epub 2019 Apr 20
  11. O590 Schatz A, Kelbsch C, Zeitz C, Kohl S, Zrenner E, Gekeler F, Wilhelm H, Wilhelm B, Willmann G: Disinhibition of intrinsic photosensitive retinal ganglion cells in patients with X-linked congenital stationary night blindness. Graefes Arch Clin Exp Ophthalmol. 2019 Jun; 257(6):1207-1215. doi: 10.1007/s00417-019-04319-w. Epub 2019 Apr 13.
  12. O589 Nasser F, Kurtenbach A, Kohl S, Obermaier C, Stingl K, Zrenner E: Retinal dystrophies with bull's-eye maculopathy along with negative ERGs. Doc Ophthalmol. 2019 Aug; 139(1):45-57. doi: 10.1007/s10633-019-09694-7. Epub 2019 Apr 3
  13. O588 Peters T, Seitz IP, Michalakis S, Biel M, Wilhelm B, Reichel FF, Ochakovski GA, Zrenner E, Ueffing M, Korbmacher B, Korte S, Bartz-Schmidt KU, Fischer MD, Rd-Cure C: Safety and toxicology of ocular gene therapy with recombinant AAV Vector rAAV.hCNGA3 in non-human primates. Hum Gene Ther Clin Dev. 2019 Jun;30(2):50-56. doi: 10.1089/humc.2018.188
  14. O587 Ervin AM, Strauss RW, Ahmed MI, Birch D, Cheetham J, Ferris FL 3rd, Ip MS, Jaffe GJ, Maguire MG, Schönbach EM, Sadda SR, West SK, Scholl HPN; ProgStar Study Group: A workshop on measuring the progression of atrophy secondary to Stargardt disease in the ProgStar studies: findings and lessons learned. Transl Vis Sci Technol. 2019 Apr 12;8(2):16. doi: 10.1167/tvst.8.2.16. eCollection 2019 Apr.
  15. O586 Vidal-Gil L, Sancho-Pelluz J, Zrenner E, Oltra M, Sahaboglu A: Poly ADP ribosylation and extracellular vesicle activity in rod photoreceptor degeneration. Sci Rep. 2019 Mar 6; 9(1):3758. doi: 10.1038/s41598-019-40215-3
  16. O585 Zeitz C, Michiels C, Neuillé M, Friedburg C, Condroyer C, Boyard F, Antonio A, Bouzidi N, Milicevic D, Veaux R, Tourville A, Zoumba A, Seneina I, Foussard M, Andrieu C, Preising M, Blanchard S, Saraiva JP, Mesrob L, Le Floch E, Jubin C, Meyer V, Blanché H, Boland A, Deleuze JF, Sharon D, Drumare I, Defoort-Dhellemmes S, De Baere E E, Leroy BP, Zanlonghi X, Casteels I, de Ravel TJ, Balikova I, Koenekoop R, Laffargue F, McLean R, Gottlob I, Bonneau D, Schordert DF, Munier F, McKibbin M, Prescott K, Pelletier V, Dollfuss H, Perdomo-Trujillo Y, Faure C, Reiff C, Wissinger B, Meunier I, Kohl S, Banin E, Zrenner E, Jurklies B, Lorenz B, Sahel JA, Audo I: Where are the missing gene defects in inherited retinal disorders? Intronic and synonymous variants contribute at least to 4% of CACNA1F-mediated inherited retinal disorders. Hum Mutat. 2019 Jun; 40(6):765-787. doi: 10.1002/humu.23735. Epub 2019 Mar 28
  17. O584 Kuehlewein L, Troelenberg N, Stingl K, Schleehauf S, Kusnyerik A, Jackson TL, MacLaren RE, Chee C, Roider J, Wilhelm B, Gekeler F, Bartz-Schmidt KU, Zrenner E, Stingl K: Changes in microchip position after implantation of a subretinal vision prosthesis in humans. Acta Ophthalmol. 2019 Sep; 97(6):e871-e876. doi: 10.1111/aos.14077. Epub 2019 Feb 28
  18. O583 Nasser F., Mulahasanovic L., Alkhateeb M., Biskup S., Stingl K., Zrenner E: Hypotrichosis with cone-rod dystrophy in a patient with cadherin 3 (CDH3) mutation. Doc Ophthalmol. (2019) 138:153–160, doi: 10.1007/s10633-019-09675-w. Epub 2019 Feb 1
  19. O582 Strasser T, Nasser F, Langrová H, Zobor D, Lisowski Ł, Hillerkuss D, Sailer C,Kurtenbach A, Zrenner E: Objective assessment of visual acuity: a refined model for analyzing the sweep VEP. Doc Ophthalmol. 2019 138:97–116, doi: 10.1007/s10633-019-09672-z. Epub Jan 29.
  20. O581 Kuehlewein L, Schöls L, Llavona P, Grimm A, Biskup S, Zrenner E, Kohl S: Phenotypic spectrum of autosomal recessive retinitis Pigmentosa without posterior column ataxia caused by mutations in the FLVCR1 gene. Graefes Arch Clin Exp Ophthalmol. (2019) 257:629–638, doi: 10.1007/s00417-018-04233-7. Epub 2019 Jan 17
  21. O580 William A, Kohl S, Zeitz C, Willmann G, Zrenner E, Bartz-Schmidt KU, Gekeler F, Schatz A: Macular sensitivity in patients with congenital stationary night-blindness. Br J Ophthalmol. 2019 Oct; 103(10):1507-1510. doi: 10.1136/bjophthalmol-2018-313072. Epub 2018 Dec 20

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2018

  1. O579 Haq W, Dietter J, Zrenner E: Electrical activation of degenerated photoreceptors in blind mouse retina elicited network-mediated responses in different types of ganglion cells. Sci Rep. 2018 Nov 19; 8(1):16998. doi: 10.1038/s41598-018-35296-5
  2. O578 Wagner S, Zrenner E, Strasser T: Ciliary muscle thickness profiles derived from optical coherence tomography images. Biomed Opt Express. 2018 Oct 1;9(10):5100-5114. doi: 10.1364/BOE.9.005100. eCollection 2018 Oct 1
  3. O577 Fischer MD, Ochakovski GA, Beier B, Seitz IP, Vaheb Y, Kortuem C, Reichel FFL, Kuehlewein L, Kahle NA, Peters T, Girach A, Zrenner E, Ueffing M, MacLaren RE, Bartz-Schmidt K, Wilhelm B: Changes in retinal sensitivity after gene therapy in choroideremia. Retina. 2020 Jan; 40(1):160-168. doi: 10.1097/IAE.0000000000002360.
  4. O576 Rathbun DL, Ghorbani N, Shabani H, Zrenner E, Hosseinzadeh Z: Spike-triggered average electrical stimuli as input filters for bionic vision-a perspective. J Neural Eng. 2018 Dec; 15(6):063002. doi: 10.1088/1741-2552/aae493. Epub 2018 Sep 27
  5. O575 Kahle NA, Peters T, Zobor D, Kuehlewein L, Kohl S, Zhour A, Werner A, Seitz IP, Sothilingam V, Michalakis S, Biel M, Ueffing M, Zrenner E, Bartz-Schmidt KU, Fischer MD, Wilhelm BJC: Development of methodology and study protocol: safety and efficacy of a single subretinal injection of rAAV.hCNGA3 in patients with CNGA3-linked achromatopsia investigated in an exploratory dose-escalation Trial. Hum Gene Ther Clin Dev. 2018 Sep; 29(3):121-131. doi: 10.1089/humc.2018.088
  6. O574 Kong X, Fujinami K, Strauss RW, Munoz B, West SK, Cideciyan AV, Michaelides M, Ahmed M, Ervin AM, Schönbach E, Cheetham JK, Scholl HPN; ProgStar Study Group: Visual acuity change over 24 months and its association with foveal phenotype and genotype in individuals with stargardt disease: ProgStar study report No. 10. JAMA Ophthalmol. 2018 Aug 1;136(8):920-928. doi: 10.1001/jamaophthalmol.2018.2198.
  7. O573 Strauss RW, Muñoz B, Ahmed MI, Bittencourt M, Schönbach EM, Michaelides M, Birch D, Zrenner E, Ervin AM, Charbel Issa P, Kong J, Wolfson Y, Shah M, Bagheri S, West S, Scholl HPN; for the ProgStar-4 Study Group: The progression of the Stargardt disease type 4 (ProgStar-4) study: design and baseline characteristics (ProgStar-4 Report No. 1). Ophthalmic Res. 2018; 60(3):185-194. doi: 10.1159/000491791. Epub 2018 Aug 15
  8. O572 Zobor D, Zobor G, Hipp S, Baumann B, Weisschuh N, Biskup S, Sliesoraityte I, Zrenner E, Kohl S: Phenotype variations caused by mutations in the RP1L1 gene in a large mainly german cohort. Invest Ophthalmol Vis Sci. 2018 Jun 1; 59(7):3041-3052. doi: 10.1167/iovs.18-24033
  9. O571 Kurtenbach A, Hahn G, Kernstock C, Hipp S, Zobor D, Stingl K, Kohl S, Bonnet C, Mohand-Saïd S, Sliesoraityte I, Sahel JA, Audo I, Fakin A, Hawlina M, Testa F, Simonelli F, Petit C, Zrenner E: Usher syndrome and color vision. Curr Eye Res. 2018 Oct; 43(10) :1295-1301. doi: 10.1080/02713683.2018.1501804. Epub 2018 Jul 30
  10. O570 Kelbsch C, Jalligampala A, Strasser T, Richter P, Stingl K, Braun C, Rathbun DL, Zrenner E, Wilhelm H, Wilhelm B, Peters T, Stingl K: Phosphene perception and pupillary responses to sinusoidal electrostimulation - for an objective measurement of retinal function. Exp Eye Res. 2018 Nov;176:210-218. doi: 10.1016/j.exer.2018.07.010. Epub 2018 Jul 10
  11. O569 Strauss RW, Kong X, Bittencourt MG, Ho A, Jha A, Schönbach EM, Ahmed MI, Muñoz B, Ervin AM, Michaelides M, Birch DG, Sahel JA, Sunness JS, Zrenner E, Bagheri S, Ip M, Sadda S, West S, Scholl HPN; for the SMART Study Group: Scotopic microperimetric assessment of rod function in Stargardt disease (SMART) study: design and baseline characteristics (Report No. 1). Ophthalmic Res. 2019; 61(1):36-43. doi: 10.1159/000488711. Epub 2018 Jun 25.
  12. O568 Fujinami K, Strauss RW, Chiang JP, Audo IS, Bernstein PS, Birch DG, Bomotti SM, Cideciyan AV, Ervin AM, Marino MJ, Sahel JA, Mohand-Said S, Sunness JS, Traboulsi EI, West S, Wojciechowski R, Zrenner E, Michaelides M, Scholl HPN; On behalf of the ProgStar Study Group; ProgStar Study Group: Detailed genetic characteristics of an international large cohort of patients with Stargardt disease: ProgStar study report 8. Br J Ophthalmol 2019;103:390–397. doi:10.1136/bjophthalmol-2018-312064 Epub 20 June 2018
  13. O567 Haq W, Dietter J, Bolz S, Zrenner E: Feasibility study for a glutamate driven subretinal prosthesis: local subretinal application of glutamate on blind retina evoke network-mediated responses in different types of ganglion cells. J Neural Eng. 2018 Aug; 15(4):045004. doi: 10.1088/1741-2552/aac811. Epub 2018 Jun 19
  14. O566 Schönbach EM, Strauss RW, Kong X, Muñoz B, Ibrahim MA, Sunness JS, Birch DG, Hahn GA, Nasser F, Zrenner E, Sadda SR, West SK, Scholl HPN; ProgStar Study Group: Longitudinal changes of fixation location and stability within 12 months in Stargardt disease: ProgStar Report No. 12. Am J Ophthalmol. 2018 Sep; 193:54-61. doi: 10.1016/j.ajo.2018.06.003. Epub 2018 Jun 8
  15. O565 Charbel Issa P, Reuter P, Kühlewein L, Birtel J, Gliem M, Tropitzsch A, Whitcroft KL, Bolz HJ, Ishihara K, MacLaren RE, Downes SM, Oishi A, Zrenner E, Kohl S, Hummel T: Olfactory dysfunction in patients with CNGB1-associated retinitis pigmentosa. JAMA Ophthalmol. 2018 Jul 1; 136(7):761-769. doi: 10.1001/jamaophthalmol.2018.1621
  16. O564 Edwards TL, Cottriall CL, Xue K, Simunovic MP, Ramsden JD, Zrenner E, MacLaren RE: Assessment of the electronic RETINAL IMPLANT Alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa. Ophthalmology. 2018 Mar; 125(3):432-443. doi: 10.1016/j.ophtha.2017.09.019. Epub 2017 Oct 27.
  17. O563 Gekeler K, Bartz-Schmidt KU, Sachs H, MacLaren RE, Stingl K, Zrenner E, Gekeler F: Implantation, removal and replacement of subretinal electronic implants for restoration of vision in patients with retinitis Pigmentosa. Curr Opin Ophthalmol. 2018 May; 29(3):239-247. doi: 10.1097/ICU.0000000000000467

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2017

  1. O562 Kuehlewein L, Kitiratschky V, Gosheva M, Edwards TL, MacLaren RE, Groppe M, Kusnyerik A, Soare C, Jackson TL, Sun CH, Chee C, Sachs H, Stingl K, Wilhelm B, Gekeler F, Bartz-Schmidt KU, Zrenner E, Stingl K: Optical coherence tomography in patients with the subretinal implant RETINA IMPLANT Alpha IMS. Ophthalmic Surg Lasers Imaging Retina. 2017 Dec 1; 48(12):993-999. doi: 10.3928/23258160-20171130-06
  2. O561 Nasser F, Weisschuh N, Maffei P, Milan G, Heller C, Zrenner E, Kohl S, Kuehlewein L: Ophthalmic features of cone-rod dystrophy caused by pathogenic variants in the ALMS1 gene. Acta Ophthalmol. 2018: 96: e445–e454. doi: 10.1111/aos.13612. Epub 2017 Nov 30
  3. O560 Strasser T, Peters T, Jägle H, Zrenner E: ElVisML: an open data format for the exchange and storage of electrophysiological data in ophthalmology. Doc Ophthalmol. 2018 Feb; 136(1):75-92. doi: 10.1007/s10633-017-9618-6. Epub 2017 Nov 11.
  4. O559 Kong X, West SK, Strauss RW, Munoz B, Cideciyan AV, Michaelides M, Ho A, Ahmed M, Schönbach EM, Cheetham JK, Ervin AM, Scholl HPN; ProgStar study group: Progression of Visual Acuity and Fundus Autofluorescence in Recent-Onset Stargardt Disease: ProgStar Study Report #4. Ophthalmol Retina. 2017 Nov - Dec;1(6):514-523. doi: 10.1016/j.oret.2017.02.008. Epub 2017 Apr 28
  5. O558 Seitz IP, Michalakis S, Wilhelm B, Reichel FF, Ochakovski GA, Zrenner E, Ueffing M, Biel M, Wissinger B, Bartz-Schmidt KU, Peters T, Fischer MD; for the RD-CURE Consortium: Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates. Invest Ophthalmol Vis Sci. 2017 Nov 1; 58(13):5792-5801. doi: 10.1167/iovs.17-22473
  6. O557 Mayer AK, Van Cauwenbergh C, Rother C, Baumann B, Reuter P, De Baere E, Wissinger B, Kohl S, ACHM Study Group: CNGB3 mutation spectrum including copy number variations in 552 achromatopsia patients. Hum Mutat. 2017 Nov; 38(11):1579-1591. doi: 10.1002/humu.23311. Epub 2017 Aug 28
  7. O556 Schönbach EM, Wolfson Y, Strauss RW, Ibrahim MA, Kong X, Muñoz B, Birch DG, Cideciyan AV, Hahn GA, Nittala M, Sunness JS, Sadda SR, West SK, Scholl HPN, ProgStar Study Group: Macular sensitivity measured with microperimetry in Stargardt disease in the progression of atrophy secondary to Stargardt disease (ProgStar) Study: Report No. 7. JAMA Ophthalmol. 2017 Jul 1;135(7):696-703. doi: 10.1001/jamaophthalmol.2017.1162.
  8. O555 Hosseinzadeh Z, Jalligampala A, Zrenner E, Rathbun DL: The spatial extent of epiretinal electrical stimulation in the healthy mouse retina. Neurosignals. 2017; 25(1):15-25. doi: 10.1159/000479459. Epub 2017 Jul 26.
  9. O554 Sahaboglu A, Sharif A, Feng L, Secer E, Zrenner E, Paquet-Durand F: Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34. PLoS One. 2017 Jul 19; 12(7):e0181374. doi: 10.1371/journal.pone.0181374. eCollection 2017.
  10. O553 Bellingrath JS, Ochakovski GA, Seitz IP, Kohl S, Zrenner E, Hanig N, Prokisch H, Weber BH, Downes SM, Ramsden S, MacLaren RE, Fischer MD: High symmetry of visual acuity and visual fields in RPGR-linked retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2017 Sep 1; 58(11):4457-4466. doi: 10.1167/iovs.17-22077.
  11. O552 Stingl K, Schippert R, Bartz-Schmidt KU, Besch D, Cottriall CL, Edwards TL, Gekeler F, Greppmaier U, Kiel K, Koitschev A, Kühlewein L, MacLaren RE, Ramsden JD, Roider J, Rothermel A, Sachs H, Schröder GS, Tode J, Troelenberg N, Zrenner E: Interim results of a multicenter trial with the new electronic subretinal implant Alpha AMS in 15 patients blind from inherited retinal degenerations. Front Neurosci. 2017 Aug 23; 11:445. doi: 10.3389/fnins.2017.00445. eCollection 2017
  12. O551 Stingl K, Mayer A-K, Llavona P, Mulahasanovic L, Rudolph G, Jacobson S G, Zrenner E, Kohl S, Wissinger B, Weisschuh N: CDHR1 mutations in retinal dystrophies. Sci Rep. 2017 Aug 1; 7(1):6992. doi: 10.1038/s41598-017-07117-8.
  13. O550 Sekhar S, Jalligampala A, Zrenner E, Rathbun D.L: Correspondence between visual and electrical input filters of ON and OFF mouse retinal ganglion cells. J Neural Eng. 2017 Aug; 14(4):046017. doi: 10.1088/1741-2552/aa722c.
  14. O549 Zrenner E: Behandlungsmöglichkeiten für Patienten mit erblichen Netzhautdystrophien.Karger Kompass Ophthalmol 2017; 3:72–74, doi: 10.1159/000472159
  15. O548 Peters T, Kim SW, Castro V, Stingl K, Strasser T, Bolz S, Schraermeyer U, Mihov G, Zong M, Andres-Guerrero V, Herrero Vanrell R, Dias AA, Cameron NR, Zrenner E: Evaluation of polyesteramide (PEA) and polyester (PLGA) microspheres as intravitreal drug delivery systems in albino rats. Biomaterials. 2017 Apr; 124:157-168. doi: 10.1016/j.biomaterials.2017.02.006. Epub 2017 Feb 7.
  16. O547 Lisowska J, Lisowski L, Kelbsch C, Maeda F, Richter P, Kohl S, Zobor D, Strasser T, Stingl K, Zrenner E, Peters T, Wilhelm H, Fischer MD, Wilhelm B; RD-CURE Consortium: Development of a chromatic pupillography protocol for the first gene therapy trial in patients with CNGA3-linked achromatopsia. Invest Ophthalmol Vis Sci. 2017 Feb 1; 58(2):1274-1282. doi: 10.1167/iovs.16-20505.
  17. O546 Kurtenbach A, Kramer S, Strasser T, Zrenner E, Langrová H: The importance of electrode position in visual electrophysiology. Doc Ophthalmol.134, P 129-134, doi: 10.1007/s10633-017-9579-9. Epub 2017 Feb 21.
  18. O545 Zobor D, Werner A, Stanzial F, Benedicenti F, Rudolph G, Kellner U, Hamel C, Andréasson S, Zobor G, Strasser T, Wissinger B, Kohl S, Zrenner E; RD-CURE Consortium: The clinical phenotype of CNGA3-related achromatopsia: pretreatment characterization in preparation of a gene replacement therapy trial. Invest Ophthalmol Vis Sci. 2017 Feb 1; 58(2):821-832. doi: 10.1167/iovs.16-20427.
  19. O544 Jalligampala A, Sekhar S, Zrenner E, Rathbun DL: Optimal voltage stimulation parameters for network-mediated responses in wild type and rd10 mouse retinal ganglion cells. J Neural Eng. 2017 Apr; 14(2):026004. doi: 10.1088/1741-2552/14/2/026004. Epub 2017 Feb 3.
  20. O543 Schatz A, Pach J, Gosheva M, Naycheva L, Willmann G, Wilhelm B, Peters T, Bartz-Schmidt KU, Zrenner E, Messias A, Gekeler F: Transcorneal electrical stimulation for patients with retinitis pigmentosa: A prospective, randomized, sham-controlled follow-up study over 1 year. Invest Ophthalmol Vis Sci. 2017 Jan 1; 58(1):257-269. doi: 10.1167/iovs.16-19906.
  21. O542 Strasser T, Langrova H, Sundermeier S, Hillerkuss D, Stingl K, Durst W, Kurtenbach A, Zrenner E, Zobor D: The Tuebingen Scotopic Threshold Test (TSTT). IEEE J Biomed Health Inform. 2018 Mar; 22(2):607-610. doi: 10.1109/JBHI.2017.2648891. Epub 2017 Jan 5
  22. O541 Kuehlewein L, Nasser F, Gloeckle N, Kohl S, Zrenner E: Fundus albipunctatus associated with cone dysfunction. Retin Cases Brief Rep. 2017 Winter; 11 Suppl 1:S73-S76. doi: 10.1097/ICB.0000000000000420.

2016

  1. O540 Jiao K, Sahaboglu A, Zrenner E, Ueffing M, Ekström PAR, Paquet-Durand F: Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations. Cell Death Discov. 2016 Jul 4; 2:16040. doi: 10.1038/cddiscovery.2016.40. eCollection 2016.
  2. O539 Kong X, Strauss RW, Michaelides M, Cideciyan AV, Sahel JA, Muñoz B, West S, Scholl HP; ProgStar Study Group: Visual acuity loss and associated risk factors in the retrospective progression of Stargardt disease study (ProgStar Report No. 2). Ophthalmology 2016 Sep; 123(9):1887-97. doi:10.1016/j.ophtha.2016.05.027. Epub 2016 Juli 2
  3. O538 Sahaboglu A, Barth M, Secer E, Amo EM, Urtti A, Arsenijevic Y, Zrenner E, Paquet-Durand F: Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration. Sci Rep. 2016 Dec 22; 6:39537. doi: 10.1038/srep39537.
  4. O537 Strauss RW, Muñoz B, Ho A, Jha A, Michaelides M, Cideciyan AV, Audo I, Birch DG, Hariri AH, Nittala MG, Sadda S, West S, Scholl HPN; ProgStar Study Group: Progression of Stargardt disease as determined by fundus autofluorescence in the retrospective progression of Stargardt disease study (ProgStar Report No. 9). JAMA Ophthalmol. 2017 Nov 1;135(11):1232-1241. doi: 10.1001/jamaophthalmol.2017.4152.
  5. 5. O536 Kong X, Strauss RW, Cideciyan AV, Michaelides M, Sahel JA, Munoz B, Ahmed M, Ervin AM, West SK, Cheetham JK, Scholl HPN; ProgStar Study Group: Visual acuity change over 12 months in the prospective progression of atrophy secondary to Stargardt disease (ProgStar) study: ProgStar Report Number 6. Ophthalmology. 2017 Nov;124(11):1640-1651. doi: 10.1016/j.ophtha.2017.04.026. Epub 2017 May 23.
  6. 6. O535 Langlo CS, Erker LR, Parker M, Patterson EJ, Higgins BP, Summerfelt P, Razeen MM, Collison FT, Fishman GA, Kay CN, Zhang J, Weleber RG, Yang P, Pennesi ME, Lam BL, Chulay JD, Dubra A, Hauswirth WW, Wilson DJ, Carroll J; ACHM-001 study group: Repeatability and longitudinal assessment of foveal cone structure in CNGB3-associated achromatopsia. Retina. 2017 Oct;37(10):1956-1966. doi: 10.1097/IAE.0000000000001434.
  7. O534 Testa F, Melillo P, Bonnet C, Marcelli V, de Benedictis A, Colucci R, Gallo B, Kurtenbach A, Rossi S, Marciano E, Auricchio A, Petit C, Zrenner E, Simonelli F: Clinical presentation and disease course of Usher syndrome because of mutations in MYO7A or USH 2A. Retina. 2017 Aug; 37(8):1581-1590, doi: 10.1097/IAE.0000000000001389, Epub 2016 Nov 8
  8. O533 Strauss RW, Muñoz B, Ho A, Jha A, Michaelides M, Mohand-Said S, Cideciyan AV, Birch D, Hariri AH, Nittala MG, Sadda S, Scholl HPN; ProgStar Study Group: Incidence of atrophic lesions in Stargardt disease in the progression of atrophy secondary to Stargardt disease (ProgStar) study: Report No. 5. JAMA Ophthalmol. 2017 Jul 1;135(7):687-695. doi: 10.1001/jamaophthalmol.2017.1121.
  9. O532 Schönbach EM, Ibrahim MA, Strauss RW, Birch DG, Cideciyan AV, Hahn GA, Ho A, Kong X, Nasser F, Sunness JS, Zrenner E, Sadda SR, West SK, Scholl H, for the Progression of Stargardt Disease Study Group: Fixation location and stability using the MP-1 microperimeter in Stargardt disease: ProgStar Report No. 3. Ophthalmol Retina. 2017 Jan - Feb; 1(1):68-76. doi: 10.1016/j.oret.2016.08.009. Epub 2016 Oct 31
  10. O531 Stingl K, Bartz-Schmidt KU, Braun A, Gekeler F, Greppmaier U,.Schatz A, Stett A, Strasser T, Kitiratschky V, Zrenner E: Transfer characteristics of subretinal visual implants: corneally recorded implant responses. Doc Ophthalmol. 2016 Oct; 133(2):81-90. Epub 2016 Aug 10.
  11. O530 Röck T, Naycheva L, Willmann G, Wilhelm B, Peters T, Zrenner E, Bartz-Schmidt KU, Gekeler F und Schatz A: [Transcorneal electrical stimulation in primary open angle glaucoma]. German. Ophthalmologe 2017 114:922–929 doi 10.1007/s00347-016-0415-5 Epup13. Dezember 2016
  12. O529 Bonnet C, Riahi Z, Chantot-Bastaraud S, Smagghe L, Letexier M, Marcaillou C, Lefèvre GM, Hardelin JP, El-Amraoui A, Singh-Estivalet A, Mohand-Saïd S, Kohl S, Kurtenbach A, Sliesoraityte I, Zobor D, Gherbi S, Testa F, Simonelli F, Banfi S, Fakin A, Glavač D, Jarc-Vidmar M, Zupan A, Battelino S, Martorell Sampol L, Claveria MA, Catala Mora J, Dad S, Møller LB, Rodriguez Jorge J, Hawlina M, Auricchio A, Sahel JA, Marlin S, Zrenner E, Audo I, Petit C: An innovative strategy for the molecular diagnosis of Usher syndrome identifies causal biallelic mutations in 93% of European patients. Eur J Hum Genet. 2016 Dec; 24(12):1730-1738. doi: 10.1038/ejhg.2016.99. Epub 2016 Jul 27.
  13. O528 Langlo CS, Patterson EJ, Higgins BP, Summerfelt P, Razeen MM, Erker LR, Parker M, Collison FT, Fishman GA, Kay CN, Zhang J, Weleber RG, Yang P, Wilson DJ, Pennesi ME, Lam BL, Chiang J, Chulay JD, Dubra A, Hauswirth WW, Carroll J; ACHM-001 Study Group: Residual foveal cone structure in CNGB3-associated achromatopsia. Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):3984-95. doi: 10.1167/iovs.16-19313.
  14. O527 Sekhar S, Jalligampala A, Zrenner E, Rathbun DL: Tickling the retina: integration of subthreshold electrical pulses can activate retinal neurons. J Neural Eng. 2016 Aug; 13(4):046004. doi: 10.1088/1741-2560/13/4/046004. Epub 2016 May 17.
  15. O526 Strauss RW, Ho A, Muñoz B, Cideciyan AV, Sahel JA, Sunness JS, Birch DG, Bernstein PS, Michaelides M, Traboulsi EI, Zrenner E, Sadda S, Ervin AM, West S, Scholl HP; Progression of Stargardt Disease Study Group: The natural history of the progression of atrophy secondary to Stargardt disease (ProgStar) studies: design and baseline characteristics: ProgStar Report No. 1. Ophthalmology. 2016 Apr; 123(4):817-28. doi: 10.1016/j.ophtha.2015.12.009. Epub 2016 Jan 16.

2015

  1. O525 Scholl HP, Moore AT, Koenekoop RK, Wen Y, Fishman GA, van den Born LI, Bittner A, Bowles K, Fletcher EC, Collison FT, Dagnelie G, Degli Eposti S, Michaelides M, Saperstein DA, Schuchard RA, Barnes C, Zein W, Zobor D, Birch DG, Mendola JD, Zrenner E, RET IRD 01 Study Group: Safety and proof-of-concept study of oral QLT091001 in retinitis pigmentosa due to inherited deficiencies of retinal pigment epithelial 65 protein (RPE65)or lecithin:retinol acyltransferase (LRAT). PLoS One. 2015 Dec 10; 10(12):e0143846. doi: 10.1371/journal.pone.0143846. eCollection 2015.
  2. O524 Koitschev A, Stingl K, Bartz-Schmidt KU, Braun A, Gekeler F, Greppmaier U, Sachs H, Peters T, Wilhelm B, Zrenner E, Besch D: Extraocular surgical approach for placement of subretinal implants in blind patients: lessons from cochlear-implants. J Ophthalmol. 2015; 2015:842518. doi: 10.1155/2015/842518. Epub 2015 Dec 10.
  3. O523 Kurtenbach A, Kernstock C, Zrenner E, Langrova H: Electrophysiology and colour: a comparison of methods to evaluate inner retinal function. Doc Ophthalmol. 2015 Dec; 131(3):159-67. doi: 10.1007/s10633-015-9512-z. Epub 2015 Sep 23.
  4. O522 Gekeler F, Zrenner E, Bartz-Schmidt KU: [Ocular electrical stimulation: Therapeutic application and active retinal implants for hereditary retinal degenerations]. German Ophthalmologe. 2015 Sep; 112(9):712-9. doi: 10.1007/s00347-015-0126-3.
  5. O521 Jünemann AG, Rejdak R, Huchzermeyer C, Maciejewski R, Grieb P, Kruse FE, Zrenner E, Rejdak K, Petzold A: Elevated vitreous body glial fibrillary acidic protein in retinal diseases. Graefes Arch Clin Exp Ophthalmol. 2015 Dec; 253(12):2181-6. doi: 10.1007/s00417-015-3127-7. Epub 2015 Aug 18
  6. O520 Kohl S, Zobor D, Chiang WC, Weisschuh N, Staller J, Menendez IG, Chang S, Beck SC, Garrido MG, Sothilingam V, Seeliger MW, Stanzial F, Benedicenti F, Inzana F, Héon E, Vincent A, Beis J, Strom TM, Rudolph G, Roosing S, Hollander AI, Cremers FP, Lopez I, Ren H, Moore AT, Webster AR, Michaelides M, Koenekoop RK, Zrenner E, Kaufman RJ, Tsang SH, Wissinger B, Lin JH: Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia. Nat Genet. 2015 Jul; 47(7):757-65. doi: 10.1038/ng.3319. Epub 2015 Jun 1.
  7. O519 Stingl K, Bartz-Schmidt KU, Besch D, Chee CK, Cottrial C, Gekeler F, Groppe M, Jackson TL, MacLaren RE, Koitschev A, Kusnyerik A, Neffendorf J, Nemeth J, Naeem MA, Peters T, Sachs H, Simpson A, Singh MS, Wilhelm B, Wong D, Zrenner E: Subretinal visual implant alpha IMS - Clinical trial interim report. Vision Res. 2015 Jun; 111(Pt B):149-60. doi: 10.1016/j.visres.2015.03.001. Epub 2015 Mar 23.
  8. O518 Hafed ZM, Stingl K, Bartz-Schmidt KU, Gekeler F, Zrenner E: Oculomotor behavior of blind patients seeing with a subretinal visual implant. Vision Res. 2016 Jan; 118:119-31. doi: 10.1016/j.visres.2015.04.006. Epub 2015 Apr 20.
  9. O517 Zarnowski T, Choragiewicz TJ, Schuettauf F, Zrenner E, Rejdak R, Gasior M, Zarnowska I, Thaler S: Ketogenic diet attenuates NMDA-induced damage to rat's retinal ganglion cells in an age-dependent manner. Ophthalmic Res. 2015; 53(3):162-7. doi: 10.1159/000379753. Epub 2015 Mar 27.
  10. O516 Wunderlich KA, Tanimoto N, Grosche A, Zrenner E, Pekny M, Reichenbach A, Seeliger MW, Pannicke T, Perez MT: Retinal functional alterations in mice lacking intermediate filament proteins glial fibrillary acidic protein and vimentin. FASEB J. 2015 Dec; 29(12):4815-28. doi: 10.1096/fj.15-272963. Epub 2015 Aug 6
  11. O515 Hipp S, Zobor G, Glöckle N, Mohr J, Kohl S, Zrenner E, Weisschuh N, Zobor D: Phenotype variations of retinal dystrophies caused by mutations in the RLBP1 gene. Acta Ophthalmol. 2015 Jun; 93(4):e281-6. doi: 10.1111/aos.12573. Epub 2014 Nov 27.
  12. O514 Zobor D, Strasser T, Zobor G, Schober F, Messias A, Strauss O, Batra A, Zrenner E: Ophthalmological assessment of cannabis-induced persisting perception disorder: Is there a direct retinal effect? Doc Ophthalmol. 2015 Apr; 130(2):121-30. doi: 10.1007/s10633-015-9481-2. Epub 2015 Jan 23.

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2014

  1. O513 Farinelli P, Perera A, Arango-Gonzalez B, Trifunovic D, Wagner M, Carell T, Biel M, Zrenner E, Michalakis S, Paquet-Durand F, Ekström PA: DNA methylation and differential gene regulation in photoreceptor cell death. Cell Death and Disease (2014)5, e1558; doi:10.1038/cddis.2014.512; Epup 4 December 2014
  2. O512 Willmann G, Schatz A, Fischer MD, Schommer K, Zrenner E, Bartz-Schmidt KU, Gekeler F, Gekeler K: Exposure to high altitude alters tear film osmolarity and breakup time. High Alt Med Biol. 2014 Jun; 15(2):203-7. doi: 10.1089/ham.2013.1103.
  3. O511 Zobor D, Zrenner E, Wissinger B, Kohl S, Jägle H: GUCY2D- or GUCA1A-related autosomal dominant cone-rod dystrophy: is there a phenotypic difference? Retina. 2014 Aug; 34(8):1576-87. doi: 10.1097/IAE.0000000000000129.
  4. O510 Naycheva L, Schatz A, Willmann G, Bartz-Schmidt KU, Zrenner E, Röck T, Gekeler F: Transcorneal electrical stimulation in patients with retinal artery occlusion: a prospective, randomized, sham-controlled pilot study. Ophthalmol Ther. 2013 Jun;2(1):25-39. doi: 10.1007/s40123-013-0012-5. Epub 2013 Feb 15.
  5. O509 Seitz IP, Zhour A, Kohl S, Llavona P, Peter T, Wilhelm B, Zrenner E, Ueffing M, Bartz-Schmidt KU, Fischer MD: Multimodal assessment of choroideremia patients defines pre-treatment characteristics. Graefes Arch Clin Exp Ophthalmol. 2015 Dec; 253(12):2143-50. doi: 10.1007/s00417-015-2976-4. Epub 2015 Mar 7.
  6. O508 Werginz P, Benav H, Zrenner E, Rattay F: Modeling the response of ON and OFF retinal bipolar cells during electric stimulation. Vision Res. 2015 Jun; 111(Pt B):170-81. doi: 10.1016/j.visres.2014.12.002. Epub 2014 Dec 11.
  7. O507 Haq W, Arango-Gonzalez B, Zrenner E, Euler T, Schubert T: Synaptic remodeling generates synchronous oscillations in the degenerated outer mouse retina. Front Neural Circuits. 2014 Sep 5; 8:108. doi: 10.3389/fncir.2014.00108. eCollection 2014
  8. O506 Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, Ueffing M, Paquet-Durand F: Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. PLoS One. 2014 Nov 13; 9(11):e112142. doi: 10.1371/journal.pone.0112142. eCollection 2014.
  9. O505 Ekström P.A.R, Ueffing M, Zrenner E, Paquet-Durand F: Novel in situ activity assays for the quantitative molecular analysis of neurodegenerative processes in the retina. Curr Med Chem. 2014; 21(30):3478-93.
  10. O504 Kitiratschky VBD, Stingl K, Wilhelm B, Peters T, Besch D, Sachs H, Gekeler F, Bartz-Schmidt KU, Zrenner E: Safety evaluation of "Retina Implant Alpha IMS" - a prospective clinical trial. Graefes Arch Clin Exp Ophthalmol. 2015 Mar; 253(3):381-7. doi: 10.1007/s00417-014-2797-x. Epub 2014 Sep 16.
  11. O503 Zenner HP, Pfister M, Friese N, Zrenner E, Röcken M: [Personalized molecular medicine: new paradigms in the treatment of cochlear implant and cancer patients]. German. HNO. 2014 Jul; 62(7):520-4. doi: 10.1007/s00106-014-2859-8.
  12. O502 Zrenner E, Tomaszewski K, Hamlin J, Layton G, Wood N: Effects of multiple doses of voriconazole on the vision of healthy volunteers: a double-blind, placebo-controlled study. Ophthalmic Res. 2014; 52(1):43-52. doi: 10.1159/000359952. Epub 2014 Jun 7.

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2013

  1. O501 Encke J, Benav H, Werginz P, Zrenner E, Rattay F: Investigating the influence of 3D cell morphology on neural response during electrical stimulation. Biomed Tech 2013, 58, issue-s1- doi: 10.1515 Epub 2013 Sep 7.
  2. O500 Werginz P, Benav H, Encke J, Zrenner E, Rattay F: Neural activation for different electrode designs in subretinal implants: a modeling study. Biomed Tech (Berl). 2013 Aug; 58 Suppl 1. pii: /j/bmte.2013.58.issue-s1-A/bmt-2013-4036/bmt-2013-4036.xml. doi: 10.1515/bmt-2013-4036. Epub 2013 Sep 7
  3. O499 Schultheiss M, Schommer K, Schatz A, Wilhelm B, Peters T, Fischer MD, Zrenner E, Bartz-Schmidt KU, Gekeler F, Willmann G: Pupillary light reaction during high altitude exposure. PLoS One. 2014 Feb 4; 9(2):e87889. doi: 10.1371/journal.pone.0087889. eCollection 2014.
  4. O498 Stingl K, Bartz-Schmidt KU, Gekeler F, Kusnyerik A, Sachs H, Zrenner E: Functional outcome in subretinal electronic implants depends on foveal eccentricity. Invest Ophthalmol Vis Sci. 2013 Nov 19; 54(12):7658-65. doi: 10.1167/iovs.13-12835.
  5. O497 Schatz A, Breithaupt M, Hudemann J, Niess A, Messias A, Zrenner E, Bartz-Schmidt KU, Gekeler F, Willmann G: Electroretinographic assessment of retinal function during acute exposure to normobaric hypoxia. Graefes Arch Clin Exp Ophthalmol. 2014 Jan; 252(1):43-50. doi: 10.1007/s00417-013-2504-3. Epub 2013 Nov 6.
  6. O496 Zrenner E: Fighting blindness with microelectronics. Sci Transl Med. 2013 Nov 6; 5(210):210ps16. doi: 10.1126/scitranslmed.3007399.
  7. O495 Farinelli P, Arango-Gonzalez B, Völkl J, Alesutan I, Lang F, Zrenner E, Paquet-Durand F, Ekström PA. Retinitis Pigmentosa: over-expression of anti-ageing protein klotho in degenerating photoreceptors. J Neurochem. 2013 Dec; 127(6):868-79. doi: 10.1111/jnc.12353. Epub 2013 Jul 22.
  8. O494 Stingl K, Zrenner E: Electronic approaches to restitute vision in patients with neurodegenerative diseases of the retina. Ophthalmic Res. 2013; 50(4):215-20. doi: 10.1159/000354424. Epub 2013 Sep 25.
  9. O493 Schatz A, Fischer MD, Schommer K, Zrenner E, Bartz-Schmidt KU, Gekeler F, Willmann G: Attenuation of S-cone function at high altitude assessed by electroretinography. Vision Res. 2014 Apr; 97:59-64. doi: 10.1016/j.visres.2014.02.003. Epub 2014 Feb 24.
  10. O492 Schatz A, Willmann G, Fischer MD, Schommer K, Messias A, Zrenner E, Bartz-Schmidt KU, Gekeler F: Electroretinographic assessment of retinal function at high altitude. J Appl Physiol (1985). 2013 Aug 1; 115(3):365-72. doi: 10.1152/japplphysiol.00245.2013. Epub 2013 May 30.
  11. O491 Willmann G, Schatz A, Zhour A, Schommer K, Zrenner E, Bartz-Schmidt KU, Gekeler F, Fischer MD: Impact of acute exposure to high altitude on anterior chamber geometry. Invest Ophthalmol Vis Sci. 2013 Jun 21; 54(6):4241-8. doi: 10.1167/iovs.13-12158; Epub June 4, 2013, doi: 10.1167/iovs.13-12158.
  12. O490 Röck T, Schatz A, Naycheva L, Gosheva M, Pach J, Wilhelm B, Peters T, Bartz-Schmidt KU, Zrenner E, Willmann G, Gekeler F: [Effects of transcorneal electrical stimulation in patients with Stargardt's disease]. German. Ophthalmologe. 2013 Jan; 110(1):68-73. doi: 10.1007/s00347-012-2749-y.
  13. O489 Stingl K, Gekeler F, Bartz-Schmidt KU, Kögel A, Zrenner E, Gelisken F: Fluorescein angiographic findings in eyes of patients with a subretinal electronic implant. Curr Eye Res. 2013 May; 38(5):588-96. doi: 10.3109/02713683.2013.767349. Epub 2013 Feb 14.
  14. O488 Stingl K, Bartz-Schmidt KU, Besch D, Braun A, Bruckmann A, Gekeler F, Greppmaier U, Hipp S, Hörtdörfer G, Kernstock C, Koitschev A, Kusnyerik A, Sachs H, Schatz A, Stingl KT, Peters T, Wilhelm B, Zrenner E: Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS. Proc Biol Sci. 2013 Feb 20; 280(1757):20130077. doi: 10.1098/rspb.2013.0077. Print 2013 Apr 22.
  15. O487 Jünemann AG, Stopa P, Michalke B, Chaudhri A, Reulbach U, Huchzermeyer C, Schlötzer-Schrehardt U, Kruse FE, Zrenner E, Rejdak R: Levels of aqueous humor trace elements in patients with non-exsudative age-related macular degeneration: a case-control study. PLoS One. 2013;8(2):e56734. doi: 10.1371/journal.pone.0056734. Epub 2013 Feb 15.
  16. O486 Rejdak R, Oleszczuk A, Rummelt C, Turski WA, Choragiewicz T, Nowomiejska K, Ksiazek K, Thaler S, Zarnowski T, Okuno E, Grieb P, Zrenner E, Kruse F, Junemann AG: Presence and distribution of l-kynurenine aminotransferases immunoreactivity in human cataractous lenses. Acta Ophthalmol. 2013 Sep; 91(6):e450-5. doi: 10.1111/aos.12138. Epub 2013 Apr 17.
  17. O485 Glöckle N, Kohl S, Mohr J, Scheurenbrand T, Sprecher A, Weisschuh N, Bernd A, Rudolph G, Schubach M, Poloschek C, Zrenner E, Biskup S, Berger W, Wissinger B, Neidhardt J: Panel-based next generation sequencing as a reliable and efficient technique to detect mutations in unselected patients with retinal dystrophies. Eur J Hum Genet. 2014 Jan; 22(1):99-104. doi: 10.1038/ejhg.2013.72. Epub 2013 Apr 17.
  18. O484 Kurtenbach A, Langrova H, Messias A, Zrenner E, Herbert Jägle H: A comparison of the performance of three visual evoked potential-based methods to estimate visual acuity. Doc Ophthalmol. 2013 Feb; 126(1):45-56. doi: 10.1007/s10633-012-9359-5. Epub 2012 Nov 11.
  19. O483 Peters T, Klingberg S, Zrenner E, Wilhelm B: Emotional wellbeing of blind patients in a pilot trial with subretinal implants. Graefes Arch Clin Exp Ophthalmol. 2013 Jun; 251(6):1489-93. doi: 10.1007/s00417-012-2210-6. Epub 2012 Nov 29.
  20. O482 Stingl K, Bach M, Bartz-Schmidt KU, Braun A, Bruckmann A, Gekeler F, Greppmaier U, Hörtdörfer G, Kusnyerik A, Peters T, Wilhelm B, Wilke R, Zrenner E: Safety and efficacy of subretinal visual implants in humans: methodological aspects. Clin Exp Optom. 2013 Jan; 96(1):4-13. doi: 10.1111/j.1444-0938.2012.00816.x. Epub 2012 Nov 22.
  21. O481 Prokofyeva E, Wegener A, Zrenner E: Cataract prevalence and prevention in Europe: a literature review. Acta Ophthalmol. 2013 Aug; 91(5):395-405. doi: 10.1111/j.1755-3768.2012.02444.x. Epub 2012 Jun 20.

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2012

  1. O480 Schatz A, Arango-Gonzalez B, Fischer D, Enderle H, Bolz S, Röck T, Naycheva L, Grimm C, Messias A, Zrenner E, Bartz-Schmidt KU, Willmann G, Gekeler F: Transcorneal electrical stimulation shows neuroprotective effects in retinas of light-exposed rats. Invest Ophthalmol Vis Sci. 2012 Aug 15; 53(9):5552-61. doi: 10.1167/iovs.12-10037. .(2012)
  2. O479 Zobor D, Kohl S, Wissinger B, Zrenner E, Jägle H: Rod and cone function in patients with KCNV2 retinopathy. (2012). PLoS One. 2012; 7(10):e46762. doi: 10.1371/journal.pone.0046762. Epub 2012 Oct 15. (2012)
  3. O478 Naycheva L, Schatz A, Röck T, Willmann G, Messias A , Bartz-Schmidt KU, Zrenner E and Gekeler F: Phosphene thresholds elicited by transcorneal electrical stimulation in healthy subjects and patients with retinal diseases. Invest Ophthalmol Vis Sci. 2012 Nov 1; 53(12):7440-8. doi: 10.1167/iovs.12-9612.(2012)
  4. O477 Estrada-Cuzcano A, Koenekoop R K, Senechal A, De Baere E.B.W., de Ravel T, Banfi S, Kohl S, Ayuso C, Sharon D, Hoyng C.B., Hamel C. P., Leroy B P., Ziviello C, Lopez I, Bazinet A, Wissinger B, Sliesoraityte I, Avila-Fernandez A, Littink K W., Vingolo E M., Signorini S, Banin E, Mizrahi-Meissonnier L, Zrenner E, Kellner U, Collin R W. J., den Hollander A I., Cremers F P. M., Klevering B. J: BBS1 mutations in a wide spectrum of phenotypes ranging from nonsyndromic retinitis pigmentosa to Bardet-Biedl syndrome. Arch Ophthalmol. 2012 Nov; 130(11):1425-32. doi: 10.1001/archophthalmol.2012.2434.(2012)
  5. O476 Prokofyeva E, Troeger E and Zrenner E: The special electrophysiological signs of inherited retinal dystrophies. Open Ophthalmol J. 2012;6:86-97. doi: 10.2174/1874364101206010086. Epub 2012 Oct 31.(2012)
  6. O475 Schatz A, Arango-Gonzalez B, Fischer D, Enderle H, Bolz S, Röck T, Naycheva L, Grimm C, Messias A, Zrenner E, Bartz-Schmidt KU, Willmann G, Gekeler F: Transcorneal electrical stimulation shows neuroprotective effects in retinas of light-exposed rats. Invest Ophthalmol Vis Sci. August 2012, 53:5552-5561; Epub July 17, 2012, doi:10.1167/iovs.12-10037.(2012)
  7. O474 Fischer MD, Willmann G, Schatz A, Schommer K, Zhour A, Zrenner E, Bartz-Schmidt KU, Gekeler F: Structural and functional changes of the human macula during acute exposure to high altitude. PLoS One. 2012; 7(4):e36155. doi: 10.1371/journal.pone.0036155. Epub 2012 Apr 30.(2012)
  8. O473 Zobor D, Zrenner E: [Retinitis pigmentosa - a review. Pathogenesis, guidelines for diagnostics and perspectives]. German. Ophthalmologe. 2012 May; 109(5):501-14;quiz 515. doi: 10.1007/s00347-012-2555-6.(2012)
  9. O472 Kusnyerik A, Greppmaier U, Wilke R, Gekeler F, Wilhelm B, Sachs, H G, Bartz-Schmidt K U, Klose U, Stingl K, Resch M D, Hekmat A, Bruckmann A, Karacs K, Nemeth J, Suveges I and Zrenner E: Positioning of electronic subretinal implants in blind retinitis pigmentosa patients through multimodal assessment of retinal structures. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3748-55. doi: 10.1167/iovs.11-9409.(2012)
  10. O471 Zhour A, Bolz S, Grimm C, Willmann G, Schatz A, Weber BH, Zrenner E, Fischer MD: In vivo imaging reveals novel aspects of retinal disease progression in Rs1h(-/Y) mice but no therapeutic effect of carbonic anhydrase inhibition. Vet Ophthalmol. 2012 Sep; 15 Suppl 2:123-33. doi: 10.1111/j.1463-5224.2012.01039.x. Epub 2012 Jun 4.(2012)
  11. O470 Arango-Gonzalez B, Schatz A, Bolz S, Eslava-Schmalbach J, Willmann G, Zhour A, Zrenner E, Fischer MD, Gekeler F: Effects of combined ketamine/xylazine anesthesia on light induced retinal degeneration in rats. PLoS One. 2012;7(4):e35687. doi: 10.1371/journal.pone.0035687. Epub 2012 Apr 25. Erratum in: PLoS One. 2012;7(8). doi:10.1371/annotation/d52a610e-6a56-4158-90bf-45e37f053567. (2012)
  12. O469 Trifunović D, Sahaboglu A, Kaur J, Mencl S, Zrenner E, Ueffing E, Arango-Gonzalez B and Paquet-Durand F: Neuroprotective strategies for the treatment of inherited photoreceptor degeneration. Curr Mol Med. 2012 Jun; 12(5):598-612. (2012)
  13. O468 Zrenner E: Artificial vision: Solar cells for the blind. Nature photonics 6: 344-345. (2012)
  14. O467 Stingl K, Bartz-Schmidt KU, Besch D, Gekeler F, Greppmaier U, Hörtdörfer G, Koitschev A, Peters T, Sachs H, Wilhelm B, Zrenner E: [What can blind patients see in daily life with the subretinal alpha IMS implant? Current overview from the clinical trial in Tübingen]. German. Ophthalmologe 2012 Feb; 109(2):136-41. doi: 10.1007/s00347-011-2479-6. (2012)
  15. O466 Estrada-Cuzcano A, Neveling K, Kohl S, Banin E, Rotenstreich Y, Sharon D, Falik-Zaccai T, Hipp S, Roepman R, Wissinger B, Letteboer S, Mans D, Blokland E, Kwint M, Gijsen S, van Huet R, Collin R, Scheffer H, Veltman J, Zrenner E, EuropRetDisease Cons, den Hollander AI, Klevering B: Mutations in C8orf37, encoding a ciliary protein, are associated with autosomal-recessive retinal dystrophies with early macular involvement. Am J Hum Genet. 2012 Jan 13; 90(1):102-9. doi: 10.1016/j.ajhg.2011.11.015. Epub 2011 Dec 15. (2012)
  16. O465 Schatz A, Wilke R, Strasser T, Gekeler F, Messias A, Zrenner E: Assessment of "non-recordable" electroretinograms by 9 Hz flicker stimulation under scotopic conditions. Doc Ophthalmol 2012 Feb; 124(1):27-39. doi: 10.1007/s10633-011-9302-1. Epub 2011 Dec 18. (2012)
  17. O464 Audo I, Bujakowska K, Orhan E, Poloschek CM, Defoort-Dhellemmes S, Drumare I, Kohl S, Luu TD, Zrenner E, Saraiva JP, Leroy BP, Friedburg C, Preising M, Kellner U, Wissinger B, De Baere E, Sharon D, Banin E, Casteels I, Koenekoop R, Long VW, Nguyen H, Dollfus H, Sahel JA, Bhattacharya S, Zeitz C: Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet. 2012 Feb 10; 90(2):321-30. doi: 10.1016/j.ajhg.2011.12.007. Erratum in: Am J Hum Genet. 2012 Jul 13; 91(1):209 (2012)
  18. O463 Prokofyeva E, Troeger E, Bernd A, Zrenner E: Visual acuity changes in cone and cone-rod dystrophies. Ophthalmic Physiol Opt. 2012 Jan; 32(1):53-9. doi: 10.1111/j.1475-1313.2011.00883.x. Epub 2011 Nov 18. (2012)
  19. O462 Zrenner E: (Jap Artikel) Die vorderste Front der Entwicklung des Netzhautchips; Newton Press, Tokio, NEWTON 32(2) 42-47 2012. (2012)
  20. O461 Prokofyeva E, Zrenner E: Epidemiology of major eye diseases leading to blindness in Europe: a literature review. Ophthalmic Res. 2012; 47(4):171-88. doi: 10.1159/000329603. Epub 2011 Nov 26. (2012)

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2011

  1. O460 Lukáts O, Resch M, Kusnyerik A, Gekeler F, Zrenner E, Németh J: Implants in ophthalmology Implantatumok a szemeszetben (a punctum plug-t61 a retina chip-ig). ORVOSKÉPZÉS, Budapest 2011; 4:397-8. (2011)
  2. O459 Bosse B, Zrenner E, Wilke R: Standard ERG equipment can be used to monitor functionality of retinal implants. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1089-92. doi: 10.1109/IEMBS.2011.6090254. (2011)
  3. O458 Willmann G, Fischer MD, Schatz A, Schommer K, Messias A, Zrenner E, Bartz-Schmidt KU, Gekeler F: Quantification of optic disc edema during exposure to high altitude shows no correlation to acute mountain sickness. PLoS One. 2011; 6(11):e27022. doi: 10.1371/journal.pone.0027022. Epub 2011 Nov 1. (2011)
  4. O457 Rejdak R, Junemann A, Grieb P, Thaler S, Schuettauf F, Choragiewicz T, Zarnowski T, Turski W A, Zrenner E: Kynurenic acid and kynurenine aminotransferases in retinal aging and neurodegeneration. Pharmacol Rep. 2011; 63(6):1324-34. (2011)
  5. O456 Wissinger B, Schaich S, Baumann B, Bonin M, Jägle H, Friedburg C, Varsányi B, Hoyng CB, Dollfus H, Heckenlively JR, Rosenberg T, Rudolph G, Kellner U, Salati R, Plomp A, De Baere E, Andrassi-Darida M, Sauer A, Wolf C, Zobor D, Bernd A,Leroy BP, Enyedi P, Cremers FP, Lorenz B, Zrenner E, Kohl S: Large deletions of the KCNV2 gene are common in patients with cone dystrophy with supernormal rod response. Hum Mutat. 2011 Dec; 32(12):1398-406. doi: 10.1002/humu.21580. Epub 2011 Sep 12. (2011)
  6. O455 Willmann G, Schäferhoff K, Fischer MD, Arango-Gonzalez B, Bolz S, Naycheva L, Röck T, Bonin M, Bartz-Schmidt KU, Zrenner E, Schatz A, Gekeler F: Gene expression profiling of the retina after transcorneal electrical stimulation in wild-type Brown Norway rats. Invest Ophthalmol Vis Sci. 2011 Sep 29; 52(10):7529-37. doi: 10.1167/iovs.11-7838. (2011)
  7. O454 Rejdak R, Rummelt C, Zrenner E, Grieb P, Rejdak K, Okuno E, Thaler S, Nowomiejska K, Kruse F, Turski W, Junemann AGM: Presence of L-kynurenine aminotransferase III in retinal ganglion cells and corpora amylacea in the human retina and optic nerve; Folia Neuropathol 2011; 49 (2): 132-137. (2011)
  8. O453 Kaur J, Mencl S, Sahaboglu A, Farinelli P, van Veen T, Zrenner E, Ekström P, Paquet-Durand F, Arango-Gonzalez B: Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS One. 2011; 6(7):e22181. doi: 10.1371/journal.pone.0022181. Epub 2011 Jul 12. (2011)
  9. O452 Wilke R, Gabel VP, Sachs H, Bartz Schmidt KU, Gekeler F, Besch D, Szurman P, Stett A, Wilhelm B, Peters T, Harscher A, Greppmaier U, Kibbel S, Benav H, Bruckmann A, Stingl K, Kusnyerik A, Zrenner E: Spatial resolution and perception of patterns mediated by a subretinal 16-electrode array in patients blinded by hereditary retinal dystrophies. Invest Ophthalmol Vis Sci. 2011 Jul 29; 52(8):5995-6003. doi: 10.1167/iovs.10-6946. (2011)
  10. O451 Schatz A, Willmann G, Enderle H, Sliesoraityte I, Messias A, Bartz-Schmidt KU, Zrenner E, Gekeler F: A new DTL-electrode holder for recording of electroretinograms in animals. J Neurosci Methods. 2011 Feb 15; 195(2):128-34. doi: 10.1016/j.jneumeth.2010.10.030. Epub 2010 Nov 12. (2011)
  11. O450 Prokofyeva E, Troeger E, Wilke R, Zrenner E: Early visual symptom patterns in inherited retinal dystrophies. Ophthalmologica. 2011; 226(3):151-6. doi: 10.1159/000330381. Epub 2011 Aug 10. (2011)
  12. O449 Schatz A, Röck T, Naycheva L, Willmann G, Wilhelm B, Peters T, Bartz-Schmidt KU, Zrenner E, Messias A, Gekeler F: Transcorneal electrical stimulation for patients with retinitis pigmentosa: a prospective, randomized, sham-controlled exploratory study. Invest Ophthalmol Vis Sci. 2011 Jun 23; 52(7):4485-96. doi: 10.1167/iovs.10-6932. (2011)
  13. O448 Kusnyerik A, Resch M, Roska T, Karacs K, Gekeler F, Wilke R, Benav H, Zrenner E, Süveges I, Nemeth J: Vision restoration with implants in retinal degenerations. Article in Hungarian “Látásjavító implantatumok látóhártya degenerációkban”. Orv Hetil. 2011 Apr 3; 152(14):537-45. doi: 10.1556/OH.2011.29064. (2011)
  14. O447 Estrada-Cuzcano A, Koenekoop RK, Coppieters F, Kohl S, Lopez I, Collin RW, De Baere EB, Roeleveld D, Marek J, Bernd A, Rohrschneider K, van den Born LI, Meire F, Maumenee IH, Jacobson SG, Hoyng CB, Zrenner E, Cremers EP, den Hollander AI: IQCB1 mutations in patients with leber congenital amaurosis. Invest Ophthalmol Vis Sci. 2011 Feb 11; 52(2):834-9. doi: 10.1167/iovs.10-5221. (2011)
  15. O446 Julien S, Peters T, Ziemssen F, Arango-Gonzalez B, Beck S, Thielecke H, Büth H, van Vlierberghe S, Sirova M, Rossmann P, Rihova B, Schacht E, Dubruel P, Zrenner E, Schraermeyer U: Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats. Biomaterials. 2011 Jun; 32(16):3890-8. doi: 10.1016/j.biomaterials.2011.02.016. (2011)
  16. O445 Grau T, Artemyev N O, Rosenberg T, Dollfus H, Haugen O H, Cumhur Sener E, Jurklies B, Andreasson S, Kernstock C, Larsen M, Zrenner E, Wissinger B, Kohl S: Decreased catalytic activity and altered activation properties of PDE6C mutants associated with autosomal recessive achromatopsia. Hum Mol Genet. 2011 Feb 15; 20(4):719-30. doi: 10.1093/hmg/ddq517. Epub 2010 Dec 1. (2011)
  17. O444 Zrenner E, Bartz-Schmidt KU, Benav H, Besch D, Bruckmann A, Gabel V-P, Gekeler F, Greppmaier U, Harscher A, Kibbel S, Koch J, Kusnyerik A, Peters T, Stingl K, Sachs H, Stett A, Szurman P, Wilhelm B, Wilke R: Subretinal electronic chips allow blind patients to read letters and combine them to words. Proc Biol Sci. 2011 May 22; 278(1711):1489-97. doi: 10.1098/rspb.2010.1747. Epub 2010 Nov 3. (2011)
  18. O443 Thaler S, Fiedorowicz M, Grieb P, Wypych Z, Knap N, Borowik T, Zawada K, Kaminski J, Wozniak M, Rejdak R, Zrenner E, Schuettauf F: Neuroprotective effects of tempol acyl esters against retinal ganglion cell death in a rat partial optic nerve crush model. Acta Ophthalmol. 2011 Nov; 89(7):e555-60. doi: 10.1111/j.1755-3768.2011.02180.x. Epub 2011 Jun 3. (2011)

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2010

  1. O442 Bernd AS, Voykov B, Zrenner E: [Maculopathy with areolar retinal pigment epithelium defects]. German. Ophthalmologe. 2010 Oct; 107(10):960-6. doi: 10.1007/s00347-010-2206-8. (2010)
  2. O441 Troeger E, Sliesoraityte I, Charbel Issa P, Scholl HN, Zrenner E, Wilke R: An integrated software solution for multi-modal mapping of morphological and functional ocular data. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6280-3. doi: 10.1109/IEMBS.2010.5628081. (2010)
  3. O440 Sliesoraityte I, Troeger E, Kurtenbach A, Wilke R, Zrenner E: Multimodal multidimensional imaging for visual system status assessment. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3001-4. doi: 10.1109/IEMBS.2010.5626153. (2010)
  4. O439 Langmann T, Di Gioia SA, Rau I, Stöhr H, Maksimovic NS, Corbo JC, Renner AB, Zrenner E, Kumaramanickavel G, Karlstetter M, Arsenijevic Y, Weber BHF, Gal AM, Rivolta C: Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa. Am J Hum Genet. 2010 Sep 10; 87(3):376-81. doi: 10.1016/j.ajhg.2010.07.018. Epub 2010 Aug 12. (2010)
  5. O438 Werner A, Bayer A, Schwarz G, Zrenner E, Paulus W: Effects of ageing on postreceptoral short-wavelength gain control: transient tritanopia increases with age. Vision Res. 2010 Aug 6; 50(17):1641-8. doi: 10.1016/j.visres.2010.05.004. Epub 2010 May 8. (2010)
  6. O437 Thaler S, Fiedorowicz M, Choragiewicz TJ, Bolz S, Tura A, Henke-Fahle S, Yoeruek E, Zrenner E, Bartz-Schmidt K, Ziemssen F, Schuettauf F: Toxicity testing of the VEGF inhibitors bevacizumab, ranibizumab and pegaptanib in rats both with and without prior retinal ganglion cell damage. Acta Ophthalmol. 2010 Aug; 88(5):e170-6. doi: 10.1111/j.1755-3768.2010.01927.x. Epub 2010 May 14. (2010)
  7. O436 Wunderlich KA, Leveillard T, Penkowa M, Zrenner E, Perez M: Altered expression of metallothionein-I and -II and their receptor megalin in inherited photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2010 Sep; 51(9):4809-20. doi: 10.1167/iovs.09-5073. Epub 2010 Mar 31. (2010)
  8. O435 Gekeler F, Kopp A, Sachs H, Besch D, Greppmaier U, Zrenner E, Bartz-Schmidt KU, Szurman P: Visualisation of active subretinal implants with external connections by high-resolution CT. Br J Ophthalmol. 2010 Jul; 94(7):843-7. doi: 10.1136/bjo.2009.170654 (2010)
  9. O434 Kurtenbach A, Dietrich T, Zrenner E, Langrova H: Topographical alterations of inner retinal activity during systemic hyperoxia-hypercapnia in normal subjects and patients with type 1 diabetes. Doc Ophthalmol. 2010 Jun; 120(3):229-41. doi: 10.1007/s10633-010-9217-2. Epub 2010 Jan 23. (2010)
  10. O433 Thaler S, Choragiewicz TJ, Rejdak R, Fiedorowicz M, Turski WA, Tulidowicz-Bielak M, Zrenner E, Schuettauf F, Zarnowski T: Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat-possible involvement of kynurenic acid. Graefes Arch Clin Exp Ophthalmol. 2010 Dec; 248(12):1729-35. doi: 10.1007/s00417-010-1425-7. Epub 2010 Jun 8. (2010)
  11. O432 Gekeler F, Kobuch K, Blatsios G, Zrenner E, Shinoda K: Repeated transchoroidal implantation and explantation of compound subretinal prostheses: an exploratory study in rabbits. Jpn J Ophthalmol. 2010 Sep;54(5):467-75. doi: 10.1007/s10384-010-0851-8. Epub 2010 Nov 5. (2010)
  12. O431 Trifunovic D, Dengler K, Michalakis S, Zrenner E, Wissinger B, Paquet-Durand F: cGMP-dependent cone photoreceptor degeneration in the cpfl1 mouse retina. J Comp Neurol. 2010 Sep 1; 518(17):3604-17. doi: 10.1002/cne.22416. (2010)
  13. O430 Arden GB, Gündüz MK, Kurtenbach A, Völker M, Zrenner E, Gündüz SB, Kamis U, Öztürk BT, Okudan S: A preliminary trial to determine whether prevention of dark adaptation affects the course of early diabetic retinopathy. Eye 2010 Jul; 24(7):1149-55. doi: 10.1038/eye.2009.328. Epub 2010 Feb 5. (2010)
  14. O429 Fuhrmann N, Schimpf S, Kamenisch Y, Leo-Kottler B, Alexander C, Auburger G, Zrenner E, Wissinger B, Alavi MV: Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy. Mol Neurodegener. 2010 Jun 14; 5:25. doi: 10.1186/1750-1326-5-25. (2010)
  15. O428 Sahaboglu A, Tanimoto N, Kaur J, Sancho-Pelluz J, Huber G, Fahl E, Arango-Gonzalez B, Zrenner E, Ekström P, Löwenheim H, Seeliger M, Paquet-Durand F: PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. PLoS One. 2010 Nov 23; 5(11): e15495. doi: 10.1371/journal.pone.0015495. (2010)
  16. O427 Stingl K, Greppmaier U, Wilhelm B, Zrenner E: Subretinale visuelle Implantate. Klin Monbl Augenheilkd. 2010 Dec; 227(12):940-5. doi: 10.1055/s-0029-1245830. Epub 2010 Dec 14. (2010)
  17. O426 Messias A, Zrenner E, Tzekov R, McGee D, Peters T, Wilhelm B, Baryluk A, Kubota R, Gekeler F: Single doses of all-trans-N-retinylacetamide slow down the ERG amplitude recovery after bleaching in rats. Doc Ophthalmol. 2010 Apr; 120(2):165-74. doi: 10.1007/s10633-009-9209-2. Epub 2009 Dec 11. (2010)
  18. O425 Bach M, Wilke M, Wilhelm B, Zrenner E, Wilke R: Basic quantitative assessment of visual performance in patients with very low vision. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):1255-60. doi: 10.1167/iovs.09-3512. Epub 2009 Oct 22. (2010)
  19. O424 Reinhard J, Kanis MJ, Berendschot TTJM, Schön C, Gelisken F, Trauzettel-Klosinski S, Bartz-Schmidt KU, Zrenner E: Macular pigment and fixation after macular translocation surgery. Br J Ophthalmol. 2010 Feb; 94(2):190-6. doi: 10.1136/bjo.2009.158717. Epub 2009 Aug 26. (2010)
  20. O423 Ebermann I, Phillips JB, Liebau MC, Koenekoop RK, Schermer B, Lopez I, Schäfer E, Roux AF, Dafinger C, Bernd A, Zrenner E, Claustres M, Blanco B, Nürnberg G, Nürnberg P, Ruland R, Westerfield M, Benzing T, Bolz HJ: PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome. J Clin Invest. 2010 Jun; 120(6):1812-23. doi: 10.1172/JCI39715. Epub 2010 May 3. (2010)
  21. O422 Strasser T, Peters T, Jagle H, Zrenner E, Wilke R: An integrated domain specific language for post-processing and visualizing electrophysiological signals in Java. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:4687-90. doi: 10.1109/IEMBS.2010.5626417. (2010)
  22. O421 Benav H, Bartz-Schmidt KU, Besch D, Bruckmann A, Gekeler F, Greppmaier U, Harscher A, Kibbel S, Kusnyerik A, Peters T, Sachs H, Stett A, Stingl K, Wilhelm B, Wilke R, Wrobel W, Zrenner E: Restoration of useful vision up to letter recognition capabilities using subretinal microphotodiodes. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:5919-22. doi: 10.1109/IEMBS.2010.5627549. (2010)
  23. O420 Lotz G, Peters T, Zrenner E, Wilke R: A domain model of a clinical reading center - Design and implementation. Conf Proc IEEE Eng Med Biol Soc. 2010;2010:4530-3. doi: 10.1109/IEMBS.2010.5626032. (2010)

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2009

  1. O419 Thaler S, Fiedorowicz M, Rejdak R, Choragiewicz TJ, Sulejczak D, Stopa P, Zarnowski T, Zrenner E, Grieb P, Schuettauf F: Neuroprotective effects of tempol on retinal ganglion cells in a partial optic nerve crush rat model with and without iron load. Exp Eye Res. 2010 Feb; 90(2):254-60. doi: 10.1016/j.exer.2009.10.013. Epub 2009 Nov 4 (2010)
  2. O418 Petzold A, Junemann A, Rejdak K, Zarnowski T, Thaler S, Grieb P, Kruse FE, Zrenner E, Rejdak R: A novel biomarker for retinal degeneration: vitreous body neurofilament proteins. J Neural Transm (Vienna). 2009 Dec; 116(12):1601-6. doi: 10.1007/s00702-009-0316-8. Epub 2009 Sep 22. (2009)
  3. O417 Zrenner E, Wilke R, Bartz-Schmidt KU, Gekeler F, Besch D, Benav H, Bruckmann A, Porubská K, Sachs H, Greppmaier U, Harscher A, Kibbel S, Wrobel W, Kusnyerik A, Peters T, Wilhelm B, Stett A: Subretinal microelectrode arrays allow blind retinitis pigmentosa patients to recognize letters and combine them to words. Biomedical Engineering and Informatics 2, 1-4 (2009)
  4. O416 Stübiger N, Biester S, Deuter C, Zrenner E, Besch D: Arthrogryposis multiplex congenita und retinitis pigmentosa. Ophthalmologe. 2009 Dec; 106(12):1121-5. doi: 10.1007/s00347-009-1972-7. (2009)
  5. O415 Zeitz C, Labs S, Lorenz B, Forster U, Üksti J, Kroes HY, De Baere E, Leroy BP, Cremers FPM, Wittmer M, van Genderen MM, Sahel J, Audo I, Poloschek CM, Moband-Said S, Fleischhauer JC, Hüffmeier U, Moskova-Doumanova V, Levin AV, Hamel CP, Leifert D, Munier FL, Schorderet DF, Zrenner E, Friedburg C: Genotyping microarray for CSNB-associated genes. Invest Ophthalmol Vis Sci. 2009 Dec; 50(12):5919-26. doi: 10.1167/iovs.09-3548. Epub 2009 Jul 2. (2009)
  6. O414 Audo I, Kohl S, Bart P, Leroy P, Munier F L, Guillonneau X, Mohand-Saïd S, Bujakowska K, Nandrot E F, Lorenz B, Preising M, Kellner U, Renner A B, Bernd A, Antonio A, Moskova-Doumanova V, Lancelot M-E, Poloschek M, Drumare I, Defoort-Dhellemmes S, Wissinger B, Léveillard T, Hamel C P, Schorderet D F, De Baere E, Berger W, Jacobson S G, Zrenner E, Sahel J-A, Bhattacharya S S and Zeitz C: TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet. 2009 Nov; 85(5):720-9. doi: 10.1016/j.ajhg.2009.10.013. Epub 2009 Nov 5. (2009)
  7. O413 Kitiratschky VBD, Behnen P, Kellner U, Heckenlively JR, Zrenner E, Jägle H, Kohl S, Wissinger B, Koch K: Mutations in the GUCA1A gene involved in hereditary cone dystrophies impair calcium-mediated regulation of guanylate cyclase. Hum Mutat. 2009 Aug; 30(8):E782-96. doi: 10.1002/humu.21055. (2009)
  8. O412 Prokofyeva E, Wilke R, Lotz G, Troeger E, Strasser T, Zrenner E: An epidemiological approach for the estimation of disease onset in Central Europe in central and peripheral monogenic retinal dystrophies. Graefes Arch Clin Exp Ophthalmol. 2009 Jul; 247(7):885-94. doi: 10.1007/s00417-009-1059-9. Epub 2009 Mar 11. Erratum in: Graefes Arch Clin Exp Ophthalmol. 2009 Oct; 247(10):1439. (2009)
  9. O411 Thaler S, Schuettauf F, Fiedorowicz M, Messias A, Schatz A, Choragiewicz TJ, May CA, Zrenner E, Kampik A, Haritoglou C: In vivo toxicity testing of methyl blue and aniline blue as vital dyes for intraocular surgery. Retina. 2009 Oct; 29(9):1257-65. doi: 10.1097/IAE.0b013e3181b8615b. (2009)
  10. O410 Ebermann I, Wiesen MHJ, Zrenner E, Lopez I, Pigeon R, Kohl S, Löwenheim H, Koenekoop RK, Bolz HJ: GPR98 mutations cause Usher syndrome type 2 in males. J Med Genet. 2009 Apr; 46(4):277-80. doi: 10.1136/jmg.2008.059626. (2009)

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2008

  1. O409 Sancho-Pelluz J, Arango-Gonzalez B, Kustermann S, Romero FJ, Van Veen T, Zrenner E, Ekström P, Paquet-Durand F: Photoreceptor cell death mechanisms in inherited retinal degeneration. Mol Neurobiol. 2008 Dec; 38(3):253-69. doi: 10.1007/s12035-008-8045-9. Epub 2008 Nov 4. (2008)
  2. O408 Zrenner E, Wilke R, Sachs H, Bartz-Schmidt K, Gekeler F, Besch D, Greppmaier U, Harscher A, Peters T, Wrobel G, Wilhelm B, Bruckmann A, Stett A, SUBRETStudy Group: Visual sensations mediated by subretinal microelectrode arrays implanted into blind retinitis pigmentosa patients. Biomed Tech 53, 218-220 (2008)
  3. O407 Nagy D, Schönfisch B, Zrenner E, Jägle H: Long-term follow-up of retinitis pigmentosa patients with multifocal electroretinography. Invest Ophthalmol Vis Sci. 2008 Oct; 49(10):4664-71. doi: 10.1167/iovs.07-1360. Epub 2008 Jun 19. (2008)
  4. O406 Besch D, Sachs H, Szurman P, Gülicher D, Wilke R, Reinert S, Zrenner E, Bartz-Schmidt KU, Gekeler F: Extraocular surgery for implantation of an active subretinal visual prosthesis with external connections: feasibility and outcome in seven patients. Br J Ophthalmol. 2008 Oct; 92(10):1361-8. doi: 10.1136/bjo.2007.131961. Epub 2008 Jul 28. (2008)
  5. O405 Kitiratschky VBD, Wilke R, Renner AB, Kellner U, Vadalà M, Birch DG, Wissinger B, Zrenner E, Kohl S: Mutation analysis identifies gucy2d as the major gene responsible for autosomal dominant progressive cone degeneration. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):5015-23. doi: 10.1167/iovs.08-1901. Epub 2008 May 16. (2008)
  6. O404 Kitiratschky VBD, Nagy D, Zabel T, Zrenner E, Wissinger B, Kohl S, Jägle H: Cone and cone-rod dystrophy segregating in the same pedigree due to the same novel CRX gene mutation. Br J Ophthalmol. 2008 Aug; 92(8):1086-91. doi: 10.1136/bjo.2007.133231. (2008)
  7. O403 Langrova H, Zrenner E, Kurtenbach A, Seeliger MW: Age-related changes in retinal functional topography. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):5024-32. doi: 10.1167/iovs.07-1309. Epub 2008 Jun 6. (2008)
  8. O402 Ziemssen F, Lüke M, Messias A, Beutel J, Tatar O, Zrenner E, Bartz-Schmidt KU, Tuebingen Bevacizumab Study Group: Safety monitoring in bevacizumab (Avastin) treatment: retinal function assessed by psychophysical (visual fields, colour vision) and electrophysiological (ERG/EOG) tests in two subgroups of patients. Int Ophthalmol. 2008 Apr; 28(2):101-9. Epub 2007 Jul 20. (2008)
  9. O401 Thaler S, Haritoglou C, Choragiewicz TJ, Messias A, Baryluk A, May CA, Rejdak R, Fiedorowicz M, Zrenner E, Schuettauf F: In vivo toxicity study of rhodamine 6G in the rat retina. Invest Ophthalmol Vis Sci. 2008 May;49(5):2120-6. doi: 10.1167/iovs.07-1476. (2008)
  10. O400 Kitiratschky VBD, Grau T, Bernd A, Zrenner E, Jägle H, Renner AB, Kellner U, Rudolph G, Jacobson SG, Cideciyan AV, Schaich S, Kohl S, Wissinger B: ABCA4 gene analysis in patients with autosomal recessive cone and cone rod dystrophies. Eur J Hum Genet. 2008 Jul; 16(7):812-9. doi: 10.1038/ejhg.2008.23. Epub 2008 Feb 20. (2008)
  11. O399 Becirovic E, Ebermann I, Nagy D, Zrenner E, Seeliger MW, Bolz HJ: Usher syndrome type 1 due to missense mutations on both CDH23 alleles: investigation of mRNA splicing. Hum Mutat. 2008 Mar; 29(3):452. doi: 10.1002/humu.9526. (2008)
  12. O398 Wissinger B, Dangel S, Jägle H, Hansen L, Baumann B, Rudolph G, Wolf C, Bonin M, Koeppen K, Ladewig T, Kohl S, Zrenner E, Rosenberg T: Cone dystrophy with supernormal rod response is strictly associated with mutations in KCNV2. Invest Ophthalmol Vis Sci. 2008 Feb; 49(2):751-7. doi: 10.1167/iovs.07-0471. (2008)
  13. O397 Messias A, Gekeler F, Wegener A, Dietz K, Kohler K, Zrenner E: Retinal safety of a new fluoroquinolone, pradofloxacin, in cats: assessment with electroretinography. Doc Ophthalmol. 2008 May; 116(3):177-91. Epub 2007 Oct 2. (2008)

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2007

  1. O396 Gekeler F, Szurman P, Grisanti S, Weiler U, Claus R, Greiner TO, Völker M, Kohler K, Zrenner E, Bartz-Schmidt KU: Compound subretinal prostheses with extra-ocular parts designed for human trials: successful long-term implantation in pigs. Graefes Arch Clin Exp Ophthalmol. 2007 Feb; 245(2):230-41. (2007)
  2. O395 Sailer H, Shinoda K, Blastsios G, Kohler K, Bondzio L, Zrenner E, Gekeler F: Investigation of thermal effects of infrared lasers on the rabbit retina: a study in the course of development of an active subretinal prosthesis. Graefes Arch Clin Exp Ophthalmol. 2007 Aug; 245(8):1169-78 (2007)
  3. O394 Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Teis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, El-Aziz MMA, Prescott DQ, Parapuram SK, Bickmore WA, Munro PMG, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya S: Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy. Am J Hum Genet. 2007 Nov;81(5):1098-103. Epub 2007 Sep 26. (2007)
  4. O393 Langrova H, Jägle H, Zrenner E, Kurtenbach A: The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli. Vis Neurosci. 2007 Nov-Dec; 24(6):805-16. (2007)
  5. O392 Zrenner E, Hämmerle H: Sehchips: Hoffnung für Blinde. Spektrum der Wissenschaft 6/07, Medizintechnik der Zukunft. S. 40-45 (2007)
  6. O391 Shinoda K, Rejdak R, Schuettauf F, Blatsios G, Völker M, Tanimoto N, Olcay T, Gekeler F, Lehaci C, Naskar R, Zagorski Z, Zrenner E: Early electroretinographic features of streptozotocin-induced diabetic retinopathy. Clin Exp Ophthalmol. 2007 Dec; 35(9):847-54. doi: 10.1111/j.1442-9071.2007.01607.x. (2007)
  7. O390 Schuettauf F, Thaler S, Bolz S, Fries J, Kalbacher H, Mankowska A, Zurakowski D, Zrenner E, Rejdak R: Alterations of amino acids and glutamate transport in the DBA/2J mouse retina; possible clues to degeneration. Graefes Arch Clin Exp Ophthalmol. 2007 Aug; 245(8):1157-68 (2007)
  8. O389 Zrenner E: Restoring neuroretinal function: new potentials. Doc Ophthalmol, 56-59 (2007)
  9. O388 Ebermann I, Wilke R, Lauhoff T, Lübben D, Zrenner E, Bolz HJ: Two truncating USH3A mutations, including one novel, in a German family with Usher syndrome. Mol Vis. 2007 Aug 30;13:1539-47. (2007)
  10. O387 Reinhard J, Messias A, Dietz K, MacKeben M, Lakmann R, Scholl HPN, Apfelstedt-Sylla E, Weber BHF, Seeliger MW, Zrenner E, Trauzettel-Klosinski S: Quantifying fixation in patients with Stargardt disease. Vision Res. 2007 Jul; 47(15):2076-85. Epub 2007 Jun 11. (2007)
  11. O386 Rejdak R, Rummelt C, Zrenner E, Grieb P, Zarnowski T, Okuno E, Schlötzer-Schrehardt U, Naumann GOH, Kruse F, Jünemann AGM: Immunohistochemical identification of kynurenine aminotransferases in corpora amylacea in the human retina and optic nerve. Folia Neuropathol. 2007; 45(2):66-71. (2007)
  12. O385 Zarnowski T, Rejdak R, Zielinska-Rzecka E, Zrenner E, Grieb P, Zagorski Z, Junemann A, Turski WA: Elevated concentrations of kynurenic acid, a tryptophan derivative, in dense nuclear cataracts. Curr Eye Res. 2007 Jan; 32(1):27-32 (2007)
  13. O384 Gekeler F, Gmeiner H, Völker M, Sachs H, Messias A, Eule C, Bartz-Schmidt KU, Zrenner E, Shinoda K: Assessment of the posterior segment of the cat eye by optical coherence tomography (OCT). Vet Ophthalmol. 2007 May-Jun; 10(3):173-8. (2007)
  14. O383 Schuster A, Janecke AR, Wilke R, Schmid E, Thompson DA, Utermann G, Wissinger B, Zrenner E, Gal A: The phenotype of early-onset retinal degeneration in persons with RDH12 mutations. Invest Ophthalmol Vis Sci. 2007 Apr; 48(4):1824-31. (2007)

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2006

  1. O366 Yang Z, Alvarez BV, Chakarova C, Jiang L, Karan G, Frederick JM, Zhao Y, Sauvé Y, Li X, Zrenner E, Wissinger B, Hollander den AI, Katz B, Baehr W, Cremers FP, Casey JR, Bhattacharya SS, Zhang K: Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration. Hum Mol Genet. 2005 Jan 15; 14(2):255-65. Epub 2004 Nov 24. (2005)
  2. O365 Seeliger MW, Beck SC, Pereyra-Munoz N, Dangel S, Tsai J, Luhmann UFO, Pavert van de SA, Wijnholds J, Samardzija M, Wenzel A, Zrenner E, Narfström K, Fahl E, Tanimoto N, Acar N, Tonagel F: In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy. Vision Res. 2005 Dec; 45(28):3512-9. Epub 2005 Sep 26. (2005)
  3. O364 Thompson DA, Janecke AR, Lange J, Feathers KL, Hübner CA, McHenry CJ, Stockton DW, Rammesmayer G, Lupski JR, Antinolo G, Ayuso C, Baiget M, Gouras P, Heckenlively JR, Hollander den A, Jacobson SG, Lewis RA, Sieving PA, Wissinger B, Yzer S, Zrenner E, Utermann G, Gal A: Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. Hum Mol Genet. 2005 Dec 15; 14(24):3865-75. Epub 2005 Nov 3. Erratum in: Hum Mol Genet. 2006 May 1; 15(9):1559. (2005)
  4. O363 Kohl S, Varsanyi B, Antunes GA, Baumann B, Hoyng CB, Jägle H, Rosenberg T, Kellner U, Lorenz B, Salati R, Jurklies B, Farkas A, Andreasson S, Weleber RG, Jacobson SG, Rudolph G, Castellan C, Dollfus H, Legius E, Anastasi M, Bitoun P, Lev D, Sieving P, Munier FL, Zrenner E, Sharpe LT, Cremers F, Wissinger B: CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia. Eur J Hum Genet. 2005 Mar; 13(3):302-8. (2005)
  5. O362 Mann M, Haq W, Zabel T, Guenther E, Zrenner E, Ladewig T: Age-dependent changes in the regulation mechanisms for intracellular calcium ions in ganglion cells of the mouse retina. Eur J Neurosci. 2005 Dec; 22(11):2735-43. (2005)
  6. O361 Schuster A, Apfelstedt-Sylla E, Pusch CM, Zrenner E, Thirkill CE: Autoimmune retinopathy with RPE hypersensitivity and 'negative ERG' in X-linked hyper-IgM syndrome. Ocul Immunol Inflamm. 2005 Apr-Jun; 13(2-3):235-43. (2005)
  7. O360 Schuster A, Weisschuh N, Jaegle H, Besch D, Janecke AR, Zierler H, Tippmann S, Zrenner E, Wissinger B: Novel rhodopsin mutations and genotype-phenotype correlation in patients with autosomal dominant retinitis pigmentosa. Br J Ophthalmol. 2005 Oct; 89(10):1258-64. (2005)
  8. O359 Schuster A, Pusch CM, Gamer D, Apfelstedt-Sylla E, Zrenner E, Kurtenbach A: Multifocal oscillatory potentials in CSNB1 and CSNB2 type congenital stationary night blindness. Int J Mol Med. 2005 Jan; 15(1):159-67. (2005)
  9. O358 Zrenner E: Blinde lernen wieder sehen. Wunderwelt Wissen 1:46 (2005)
  10. O357 Jacobi FK, Zrenner E, Broghammer M, Pusch CM: A genetic perspective on myopia. Cell Mol Life Sci. 2005 Apr; 62(7-8):800-8. Review. (2005)
  11. O356 Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER: Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice. J Neurosci. 2005 Feb 16; 25(7):1701-10. (2005)
  12. O355 F, Zrenner E: [Status of the subretinal implant project. An overview]. German. Ophthalmologe. 2005 Oct;102(10):941-9. (2005)

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2005

  1. O367 Yang Z, Alvarez BV, Chakarova C, Jiang L, Karan G, Frederick JM, Zhao Y, Sauvé Y, Li X, Zrenner E, Wissinger B, Hollander den AI, Katz B, Baehr W, Cremers FP, Casey JR, Bhattacharya SS, Zhang K:
    Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration. Eur J Hum Genet 14, 255-265 (2005)
  2. O354 Thompson DA, Janecke AR, Lange J, Feathers KL, Hübner CA, McHenry CJ, Stockton DW, Rammesmayer G, Lupski JR, Antinolo G, Ayuso C, Baiget M, Gouras P, Heckenlively JR, Hollander den A, Jacobson SG, Lewis RA, Sieving PA, Wissinger B, Yzer S, Zrenner E, Utermann G, Gal A:
    Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. Hum Mol Genet 14, 3865-3875 (2005)
  3. O352 Seeliger MW, Beck SC, Pereyra-Munoz N, Dangel S, Tsai J, Luhmann UFO, Pavert van de SA, Wijnholds J, Samardzija M, Wenzel A, Zrenner E, Narfström K, Fahl E, Tanimoto N, Acar N, Tonagel F:
    In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy. Vision Res 45, 3512-3519 (2005)
  4. O351 Kohl S, Varsanyi B, Antunes GA, Baumann B, Hoyng CB, Jägle H, Rosenberg T, Kellner U, Lorenz B, Salati R, Jurklies B, Farkas A, Andreasson S, Weleber RG, Jacobson SG, Rudolph G, Castellan C, Dollfus H, Legius E, Anastasi M, Bitoun P, Lev D, Sieving P, Munier FL, Zrenner E, Sharpe LT, Cremers F, Wissinger B:
    CNGB3 mutations account for 50 of all cases with autosomal recessive achromatopsia. Eur J Hum Genet 13, 302-308 (2005)
  5. O350 Mann M, Haq W, Zabel T, Guenther E, Zrenner E, Ladewig T:
    Age-dependent changes in the regulation mechanisms for intracellular calcium ions in ganglion cells of the mouse retina. Eur J Neurosci 22, 2735-2743 (2005)
  6. O349 Schuster A, Apfelstedt-Sylla E, Pusch CM, Zrenner E, Thirkill CE:
    Autoimmune retinopathy with RPE hypersensitivity and ‘negative ERG’ in X-linked hyper-IgM syndrome. Ocul Immunol Inflamm 13:235-243 (2005)
  7. O348 Schuster A, Weisschuh N, Jaegle H, Besch D, Janecke AR, Zierler H, Tippmann S, Zrenner E, Wissinger B:
    Novel rhodopsin mutations and genotype-phenotype correlation in patients with autosomal dominant retinitis pigmentosa. Brit J Ophthalmol 89, 1258-1264 (2005)
  8. O346 Schuster A, Pusch CM, Gamer D, Apfelstedt-Sylla E, Zrenner E, Kurtenbach A:
    Multifocal oscillatory potentials in CSNB1 and CSNB2 type congenital stationary night blindness. Int J Mol Med 15, 159-167 (2005)
  9. O345 Zrenner E:
    Blinde lernen wieder sehen. Wunderwelt Wissen 1:46 (2005)
  10. O343 Jacobi FK, Zrenner E, Broghammer M, Pusch CM:
    A genetic perspective on myopia. Cell Mol Life Sci 62, 800-808 (2005)
  11. O342 Ohlmann A, Scholz M, Goldwich A, Chauhan BK, Hudl K, Ohlmann AV, Zrenner E, Berger W, Cvekl A, Seeliger MW, Tamm ER:
    Ectopic Norrin Induces Growth of Ocular Capillaries and Restores Normal Retinal Angiogenesis in Norrie Disease Mutant Mice. J Neurosci 25, 1701-1710 (2005)
  12. O339 Schuster A, Apfelstedt-Sylla E, Pusch CM, Zrenner E, Thirkill CE:
    Autoimmune Retinopathy with RPE Hypersensitivity and Negative ERG in X-Linked Hyer-IgM Syndrome. Ocul Immunol Inflamm 13, 235-243 (2005)

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2004

  1. O354 Ladewig T, Fellner S, Zrenner E, Kohler K, Guenther E: BDNF regulates NMDA receptor activity in developing retinal ganglion cells. Neuroreport. 2004 Nov 15; 15(16):2495-9. (2004)
  2. O353 Gekeler F, Kobuch K, Schwahn HN, Stett A, Shinoda K, Zrenner E: Subretinal electrical stimulation of the rabbit retina with acutely implanted electrode arrays. Graefes Arch Clin Exp Ophthalmol. 2004 Jul; 242(7):587-96. Epub 2004 Jun 5. (2004)
  3. O352 Wejksza K, Rzeski W, Parada-Turska J, Zdzisinska B, Rejdak R, Kocki T, Okuno E, Kandefer-Szersen M, Zrenner E, Turski WA: Kynurenic acid production in cultured bovine aortic endothelial cells. Homocysteine is a potent inhibitor. Naunyn Schmiedebergs Arch Pharmacol. 2004 Mar; 369(3):300-4. Epub 2004 Feb 10. (2004)
  4. O351 Zarnowski T, Rejdak R, Zagorski Z, Juenemann AG, Zrenner E, Kocki T, Urbanska EM, Turski WA: Content of kynurenic acid and activity of kynurenine aminotransferases in mammalian eyes. Ophthalmic Res. 2004 Mar-Apr; 36(2):124-8. (2004)
  5. O350 Tränkner D, Jägle H, Kohl S, Apfelstedt-Sylla E, Sharpe LT, Kaupp UB, Zrenner E, Seifert R, Wissinger B: Molecular basis of an inherited form of incomplete achromatopsia. J Neurosci. 2004 Jan 7; 24(1):138-47. (2004)
  6. O349 Wright AF, Reddick AC, Schwartz SB, Ferguson JS, Aleman TS, Kellner U, Jurklies B, Schuster A, Zrenner E, Wissinger B, Lennon A, Shu X, Cideciyan AV, Stone EM, Jacobson G, Swaroop A: Mutation analysis of NR2E3 and NRL genes in enhanced S cone syndrome. Hum Mutat. 2004 Nov; 24(5):439. (2004)
  7. O348 Jägle H, Jägle C, Sérey L, Yu A, Rilk A, Sadowski B, Besch D, Zrenner E, Sharpe LT: Visual short-term effects of Viagra: double-blind study in healthy young subjects. Am J Ophthalmol. 2004 May; 137(5):842-9 (2004)
  8. O347 Völker M, Shinoda K, Sachs H, Gmeiner H, Schwarz T, Kohler K, Inhoffen W, Bartz-Schmidt KU, Zrenner E, Gekeler F: In vivo assessment of subretinally implanted microphotodiode arrays in cats by optical coherence tomography and fluorescein angiography. Graefes Arch Clin Exp Ophthalmol. 2004 Sep; 242(9):792-9. (2004)
  9. O346 Rosenberg T, Baumann B, Kohl S, Zrenner E, Jorgensen AL, Wissinger B: Variant phenotypes of incomplete achromatopsia in two cousins with GNAT2 gene mutations. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4256-62. (2004)
  10. O345 Kurtenbach A, Leo-Kottler B, Zrenner E: Inner retinal contributions to the multifocal electroretinogram: patients with Leber's hereditary optic neuropathy (LHON). Multifocal ERG in patients with LHON. Doc Ophthalmol. 2004 May; 108(3):231-40. (2004)
  11. O344 Zrenner E: Die Implantation von Sehprothesen bei progressiven Netzhautdystrophien. Teil 1: Subretinale Sehchips Augenspiegel 10, 22-24 (2004)
  12. O343 Zrenner E, Burmeister H: [Introduction to the topic of functional assessment of sporadic visual field defects]. German. Ophthalmologe. 2004 Oct; 101(10):1028-9. (2004)
  13. O342 Innocenti B, Pfeiffer S, Zrenner E, Kohler K, Guenther E: ATP-induced non-neuronal cell permeabilization in the rat inner retina. J Neurosci. 2004 Sep 29; 24(39):8577-83. (2004)
  14. O341 Zrenner E: Macular translocation in adult-onset vitelliform macular dystrophy: a therapy to be recommended? Graefes Arch Clin Exp Ophthalmol. 2004 Jun; 242(6):453-5. Epub 2004 May 11. (2004)
  15. O340 Zrenner E, Haemmerle H: Sehchips - Hoffnung für Blinde. Spektrum der Wissenschaft 2, 20-25 (2004)
  16. O339 Dalke C, Löster J, Fuchs H, Gailus-Durner V, Soewarto D, Favor J, Neuhäuser-Klaus A, Pretsch W, Gekeler F, Shinoda K, Zrenner E, Meitinger T, Hrabè de Angelis M, Graw J: Electroretinography as a screening method for mutations causing retinal dysfunction in mice. Invest Ophthalmol Vis Sci. 2004 Feb; 45(2):601-9. (2004)
  17. O338 Rejdak R, Kohler K, Kocki T, Shenk Y, Turski WA, Okuno E, Lehaci C, Zagorski Z, Zrenner E, Schuettauf F: Age-dependent decrease of retinal kynurenate and kynurenine aminotransferases in DBA/2J mice, a model of ocular hypertension. Vision Res. 2004 Mar; 44(7):655-60. (2004)
  18. O337 Zrenner E: Active subretinal implant produces neuronal stimulation for potential artificial vision. Ocular Surgery News 22/2:3-9 (2004)
  19. O336 Schuettauf F, Rejdak R, Walsko M, Frontczak-Baniewicz M, Voelker M, Blatsios G, Shinoda K, Zagorski Z, Zrenner E, Grieb P: Retinal neurodegeneration in the DBA/2J mouse-a model for ocular hypertension. Acta Neuropathol. 2004 Apr; 107(4):352-8. Epub 2004 Jan 24. (2004)
  20. O335 Rejdak R, Shenk Y, Schuettauf F, Turski WA, Okuno E, Zagorski Z, Zrenner E, Kohler K: Expression of kynurenine aminotransferases in the rat retina during development. Vision Res. 2004 Jan; 44(1):1-7. (2004)

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2003

  1. O334 Rejdak R, Zarnowski T, Turski WA, Kocki T, Zagorski Z, Zrenner E, Schuettauf F: Alterations of kynurenic acid content in the retina in response to retinal ganglion cell damage. Vision Res. 2003 Mar;43(5):497-503. (2003)
  2. O333 Zrenner E: Vitamin A und Hüftkopf-Frakturen. Retina aktuell 89/26:7 (2003)
  3. O332 Zrenner E, Blasios G, Gabel VP, Graf HG, Günther E, Kobuch K, Kohler K, Nisch W, Sachs H, Sailer H, Shinoda K, Stezle M, Stett A: Können elektronische Netzhautimplantate die Sehkraft wiederherstellen? Eine Übersicht. J Med Genet 15, 161-166 (2003)
  4. O331 Besch D, Zrenner E: Best disease. Orphanet (2003)
  5. O330 Seeliger MW, Weber BHF, Besch D, Zrenner E, Schrewe H, Mayser H: MfERG waveform characteristics in the RS1h mouse model featuring a 'negative' ERG. Doc Ophthalmol. 2003 Jul; 107(1):37-44. (2003)
  6. O329 Besch D, Jägle H, Scholl HPN, Seeliger M, Zrenner E: Inherited multifocal RPE-diseases: mechanisms for local dysfunction in global retinoid cycle gene defects. Vision Res. 2003 Dec; 43(28):3095-108. Review. (2003)
  7. O328 Rejdak R, Zielinska E, Shenk Y, Turski WA, Okuno E, Zarnowski T, Zagorski Z, Zrenner E, Kohler K: Ontogenic changes of kynurenine aminotransferase I activity and its expression in the chicken retina. Vision Res. 2003 Jun; 43(14):1513-7. (2003)
  8. O327 Baehr W, Chader G, Wu S, Zrenner E: Retinal Cell Rescue. Stem Cells, Remodelling, Neuroprotection, Apoptosis and Replacement of Retinal Neurons. Editorial. Vison Res 48:857 (2003)
  9. O326 Zrenner E: Entwicklung des subretinalen Implantats. Retina Aktuell 1, 2-3 (2003)
  10. O325 Besch D, Zrenner E: Prevention and therapy in hereditary retinal degenerations. Doc Ophthalmol. 2003 Jan; 106(1):31-5. Review. (2003)
  11. O324 van den Hurk JA, van de Pol DJ, Wissinger B, van Driel MA, Hoefsloot LH, de Wijs IJ, van den Born LI, Heckenlively JR, Brunner HG, Zrenner E, Ropers HH, Cremers FP: Novel types of mutation in the choroideremia (CHM) gene: a full-length L1 insertion and an intronic mutation activating a cryptic exon. Hum Genet. 2003 Aug; 113(3):268-75. Epub 2003 Jun 25. (2003)

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2002

  1. O323 Langrova H, Gamer D, Friedburg C, Besch D, Zrenner E, Apfelstedt-Sylla E: Abnormalities of the long flash ERG in congenital stationary night blindness of the Schubert-Bornschein type. Vision Res. 2002 May; 42(11):1475-83 (2002)
  2. O322 Becker G, Jeremic B, Pitz S, Buchgeister M, Wilhelm H, Schiefer U, Paulsen F, Zrenner E, Bamberg M: Stereotactic fractionated radiotherapy in patients with optic nerve sheath meningioma. Int J Radiat Oncol Biol Phys. 2002 Dec 1; 54(5):1422-9. (2002)
  3. O321 Laties AM, Zrenner E: Viagra (sildenafil citrate) and ophthalmology. Prog Retin Eye Res. 2002 Sep;21(5):485-506. (2002)
  4. O320 Jacobi FK, Andréasson S, Langrova H, Meindl A, Zrenner E, Apfelstedt-Sylla E, Pusch CM: Phenotypic expression of the complete type of X-linked congenital stationary night blindness in patients with different mutations in the NYX gene. Graefes Arch Clin Exp Ophthalmol. 2002 Oct; 240(10):822-8. Epub 2002 Sep 21. (2002)
  5. O319 Pitz S, Becker G, Schiefer U, Wilhelm H, Jeremic B, Bamberg M, Zrenner E: Stereotactic fractionated irradiation of optic nerve sheath meningioma: a new treatment alternative. Br J Ophthalmol. 2002 Nov; 86(11):1265-8. (2002)
  6. O318 Zrenner E: The subretinal implant: can microphotodiode arrays replace degenerated retinal photoreceptors to restore vision? Ophthalmologica. 2002; 216 Suppl 1:8-20; discussion 52-3. (2002)
  7. O317 König HH, Barry JC, Leidl R, Zrenner E: Economic evaluation of orthoptic screening: results of a field study in 121 German kindergartens. Invest Ophthalmol Vis Sci. 2002 Oct; 43(10):3209-15 (2002)
  8. O316 Rejdak R, Zarnowski T, Turski WA, Kocki T, Zagorski Z, Guenther E, Kohler K, Zrenner E: Changes of kynurenic acid content in the rat and chicken retina during ontogeny. Graefes Arch Clin Exp Ophthalmol. 2002 Aug;240(8):687-91. Epub 2002 Jun 29. (2002)
  9. O315 Wutz K, Sauer C, Zrenner E, Lorenz B, Alitalo T, Broghammer M, Hergersberg M, Chapelle de la A, Weber BHF, Wissinger B, Meindl A, Pusch CM: Thirty distinct CACNA1F mutations in 33 families with incomplete type of XLCSNB and Cacna1f expression profiling in mouse retina. Eur J Hum Genet. 2002 Aug; 10(8):449-56. (2002)
  10. O314 Dietrich K, Jacobi FK, Tippmann S, Schmidt R, Zrenner E, Wissinger B, Apfelstedt-Sylla E: A novel mutation of the RP1 gene (Lys778ter) associated with autosomal dominant retinitis pigmentosa. Br J Ophthalmol. 2002 Mar;86(3):328-32. (2002)
  11. O313 Besch D, Kurtenbach A, Apfelstedt-Sylla E, Sadowski B, Denning D, Asenbauer C, Zrenner E, Schiefer U: Visual field constriction and electrophysiological changes associated with vigabatrin. Doc Ophthalmol. 2002 Mar;104(2):151-70. (2002)
  12. O312 Scholl HPN, Schuster AM, Vonthein R, Zrenner E: Mapping of retinal function in Best macular dystrophy using multifocal electroretinography. Vision Res. 2002 Apr; 42(8):1053-61. (2002)
  13. O311 Smye S, Orpwood R, Mallot H, Mason S, Zrenner E: Mimicking the brain. Phys World , 27-31 (2002)
  14. O310 Zrenner E: Will retinal implants restore vision? Science. 2002 Feb 8; 295(5557):1022-5. Review. (2002)

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2001

  1. O309 Schwahn HN, Gekeler F, Kohler K, Kobuch K, Sachs HG, Schulmeyer F, Jakob W, Gabel VP, Zrenner E: Studies on the feasibility of a subretinal visual prosthesis: data from Yucatan micropig and rabbit. Graefes Arch Clin Exp Ophthalmol 239:961-967 (2001)
  2. O308 Schwahn HN, Gekeler F, Kohler K, Zrenner E: Stimulation des visuellen Systems durch subretinale Elektrostimulation: Tierexperimentelle Daten zur Machbarkeit einer subretinalen Netzhautprothese. Nova Acta Leopoldina 84/322:209-221 (2001)
  3. O307 Jurklies B, Weismann M, Kellner U, Zrenner E, Bornfeld N: Klinische Befunde bei autosomal-rezessivem Syndrom der Blauzapfenhypersensitivität. Ophthalmologe 98:285 -293 (2001)
  4. O306 Zrenner E: RP-Preis 2001. Retina Aktuell 4, 7-8 (2001)
  5. O305 Zrenner E, Besch D: Stand der Therapieforschung bei Netzhautdegenerationen. Retina Aktuell 4, 10-11 (2001)
  6. O304 Rejdak R, Zarnowski T, Turski WA, Okuno E, Kocki T, Zagórski Z, Kohler K, Guenther E, Zrenner E: Presence of kynurenic acid and kynurenine aminotransferases in the inner retina. Neuro Report 12 (17), 3675-3678 (2001)
  7. O303 Seeliger M, Zrenner E, Apfelstedt-Sylla E, Jaissle G: Identification of Usher syndrome subtypes by ERG implicit time. Invest Ophthalmol Vis Sci 42(12), 3066-3071 (2001)
  8. O302 Scholl HPN, Langrova H, Pusch CM, Wissinger B, Zrenner E, Apfelstedt-Sylla E: Slow and fast rod ERG pathways in patients with x-linked complete stationary night blindness carrying mutations in the NYX gene. Invest Ophthalmol Vis Sci 42 (11), 2728-2736 (2001)
  9. O301 Zrenner E, Gekeler F, Gabel VP, Graf HG, Graf M, Guenther E, Haemmerle H, Hoefflinger B, Hoff A, Kobuch K, Kohler K, Nisch W, Sachs H, Schloßhauer B, Schubert M, Schwahn H, Stelzle M, Stett A, Troeger B, Weiss S: Subretinale Implantate zur Wiederherstellungder visuellen Orientierung: Stand der Entwicklung (Subretinal implants for the restitution of visual orientation: State of the developments. Z Prakt Augenheilkd 22, 349-354 (2001)
  10. O300 Wissinger B, Gamer D, Jaegle H, Giorda R, Marx T, Mayer S, Tippmann S, Broghammer M, Jurklies B, Rosenberg T, Jacobson SG, Sener C, Tatlipinar S, Hoyng CB, Castellan C, Bitoun P, Andreasson S, Rudolph G, Kellner U, Lorenz B, Wolff G, Verellen-Dumoulin C, Schwartz M, Cremers FPM, Apefelstedt-Sylla E, Zrenner E, Salati R, Sharpe LT, and Kohl S: CNGA3 mutations in hereditary cone photoreceptor disorders. Am. J. Genet 69, 722-737 (2001)
  11. O299 Seeliger M, Grimm C, Stählberg F, Friedburg F, Jaissle G, Zrenner E, Guo H, Remé CE, Humphries P, Hofmann F, Biel M, Fariss RN, Redmond TM, Wenzel A: New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis. Nature Genetics 29, 70-74 (2001)
  12. O298 Zrenner E, Ruether K: Stand der Empfehlungen zur Gabe von Vitamin-A-Derivaten bei erblichen Netzhautdegenerationen. Retina Aktuell 81, 18-21 (2001)
  13. O297 Pesch K, Tomiuk J, Broghammer M, Zrenner E, Apfelstedt-Sylla E, Jacobi FK, Wissinger B, Pusch C: Case population must match the respective disease model: Genotype diversity causes linkage disequilibrium mapping failure in monogenic disorders. Intl J of Molecular Medicine 8, 53-58 (2001)
  14. O296 Wenzel A, Grimm C, Seeliger MW, Jaissle G, Hafezi F, Kretschmer R, Zrenner E, Remé C: Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor. Invest Ophthalmol Vis Sci 42 (7), 1653-1659 (2001)
  15. O295 Erb C, Voelcker Adler M, Wohlrab M, Zrenner E: Color-vision disturbances in patients with coronary artery diseases. Color Research and Application 26, S288-S291 (2001)
  16. O294 Pesch UEA, Leo-Kottler B, Mayer S, Jurklies B, Kellner U, Apfelstedt-Sylla E, Zrenner E, Alexander C, and Wissinger B: OPA1 mutations in patients with autosomal dominant optic atrophy and evidence for semi-dominant inheritance. Human Molecular Genetics 10 (13), 1359-1368 (2001)
  17. O293 Jacobi FK, Leo-Kottler B, Mittelviefhaus K, Zrenner E, Meyer J, Pusch CM, Wissinger B: Segregation patterns and heteroplasmy prevalence in Leber's hereditary optic neuropathy. Invest Ophthalmol Vis Sci 42 (6), 1208-1214 (2001)
  18. O292 Zrenner E, Rüther K: [Administration of vitamin A derivatives in hereditary retinal degeneration. Status of recommendations]. German. Ophthalmologe 98 (6), 526-528 (2001)
  19. O291 Eckhorn R, Stett A, Schanze T, Gekeler F, Schwahn H, Zrenner E, Wilms M, Eger M, Hesse L: [Physiological functional evaluation of retinal implants in animal models]. German. Ophthalmologe 98 (4), 369-375 (2001)
  20. O290 Kohler K, Hartmann JA, Werts S, Zrenner E: [Histological studies of retinal degeneration and biocompatibility of subretinal implants]. German. Ophthalmologe 98 (4), 364-368 (2001)
  21. O289 Zrenner E, Gekeler F, Gabel VP, Graf HG, Graf M, Guenther E, Haemmerle H, Hoefflinger B, Kobuch K, Kohler K, Nisch W, Sachs H, Schloßhauer B, Schubert M, Schwahn H, Stelzle M, Stett A, Troeger B, Weiss S: [Subretinal microphotodiode array as replacement for degenerated photoreceptors?]. German. Ophthalmologe 98 (4), 357-363 (2001)
  22. O288 Zrenner E: ["Retinal implants" - replacement of retinal functions by technical implants: a feasible way to replace vision? The spokesman of the BMBF Research Committee "Retinal Implant"]. German. Ophthalmologe 98, 353-356 (2001)
  23. O287 Scholl HPN, Langrová H, Weber BHF, Zrenner E, Apfelstedt-Sylla E: Clinical electrophysiology of two rod pathways: normative values and clinical application. Graefes Arch Clin Exp Ophthalmol 239, 71-80 (2001)
  24. O286 Gabel V, Zrenner E: Entwicklung einer subretinalen Sehprothese. Retina Aktuell 1, 12-13 (2001)
  25. O285 Wilhelm B, Lüdtke H, Peter T, Schmid R, Wilhelm H, Zrenner E: [Automated swinging flashlight test in patients with optic nerve diseases]. German. Klin Mbl Augenheilk 218, 21-25 (2001)
  26. O284 Jaissle GB, May CA, Reinhard J, Kohler K, Fauser S, Lütjen-Drecoll E, Zrenner E, Seeliger M: Evaluation of the rhodopsin knockout mouse as a model of pure cone function. Invest Ophthalmol Vis Sci 42 (2), 506-513 (2001)
  27. O283 Rizzo J, Wyatt J, Humayun M, de Juan E, Liu W, Chow A, Eckmiller R, Zrenner E, Yagi T, Abrams G: Retinal prosthesis: an encouraging first decade with major challenges ahead. Ophthalmology 108 (1), 13-14 (2001)

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2000

  1. O282 Koenig H-H, Barry JC, Leidl R, Zrenner E: [Cost effectiveness of mass orthoptic screening in kindergarten for early detection of developmental vision disorders]. German. Gesundheitswesen 2000 62, 196-206 (2000)
  2. O281 Weckerle P, Trauzettel-Klosinski S, Kamin G, Zrenner E: Task performance with the Low Vision Enhancement System (LVES). Visual Impairment Research 2, 155-162 (2000)
  3. O280 Apfelstedt-Sylla E, Besch D, Zrenner E : 9-Cis-Retinal: Eine zukünftige Therapie bei RP? Retina Aktuell 4, 6-8 (2000)
  4. O279 Thompson DA, Gyürüs P, Fleischer LL, Bingham EL, McHenry CL, Apfelstedt-Sylla E, Zrenner E, Lorenz B, Richards JE, Jacobson SG, Sieving PA, Gal A : Genetics and Phenotypes of RPE65 Mutations in inherited retinal degeneration. Invest Ophthalmol Vis Sci 41 (13), 4293-4299 (2000)
  5. O278 König HH, Barry JC, Leidl R, Zrenner E: Cost-effectiveness of orthoptic screening in kindergarten: a decision-analytic model. Strabismus 8, 79-90 (2000)
  6. O277 Zrenner E, Bach M, Dannheim F, Foerster M, Kellner U, Kolling G, Krastel H, Rassow B, Schiefer U, Weber J, Friedburg C, Sharpe LT, Wesemann W: Empfehlungen der Deutschen Ophthalmologischen Gesellschaft zur Qualitätssicherung bei sinnesphysiologischen Untersuchungen und Geräten. Ophthalmologe 97, 923-964 (2000)
  7. O276 Bauer A, Kolling G, Dietz K, Zrenner E, Schiefer U: [Are cross-eyed persons worse drivers? The effect of stereoscopic disparity on driving skills]. German. Klin Monatsbl Augenh 217, 183-189 (2000)
  8. O275 Erb C, Teistler F, Kohler K, Guenther E, Zrenner E, Thiel HJ: [Evaluating the Pro Ton applanation tonometer in rabbits]. German. Ophthalmologe 97, 788-791 (2000)
  9. O274 Seeliger MW, Narfstroem K, Reinhard J, Zrenner E, Sutter E: Continuous monitoring of the stimulated area on multifocal ERG. Doc Ophthalmol 100, 167-184 (2000)
  10. O273 Kretschmann U, Bock M, Gockeln R, Zrenner E: Clinical applications of multifocal electroretinography. Doc Ophthalmol 100, 99-113 (2000)
  11. O272 Kohl S, Baumann B, Broghammer M, Jaegle H, Sieving P, Kellner U, Spegal R, Anastasi M, Zrenner E, Sharpe LT, Wissinger B: Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3)linked to chromosome 8q21. Hum Mol Genet 9, 2107-2116 (2000)
  12. O271 Kurtenbach A, Langrova H, Zrenner E: Multifocal oscillatory potentials in type 1 diabetes without retinopathy. Invest Ophth Vis Sci 41, 3234-3241 (2000)
  13. O270 Scholl HPN, Zrenner E: Electrophysiology in the investigation of acquired retinal disorders. Surv Ophthalmol 45, 29-47 (2000)
  14. O269 Scholl HPN, Kremers J, Apfelstedt-Sylla E, Zrenner E: L- and M-cone driven ERGs are differently altered in Best's macular dystrophy. Vision Res 40, 3159-3168 (2000)
  15. O268 Zrenner E: Aktuelles zur Vitamin-A-Therapie. Retina Suisse Journal 1, 49-53 (2000)
  16. O267 Jacobi FK, Broghammer M, Pesch K, Zrenner E, Berger W, Meindl A, Pusch CM: Physical mapping and exclusion of GPR34 as the causative gene for congenital stationary night blindness type 1. Hum Genet 107, 89-91 (2000)
  17. O266 Stett A, Barth W, Weiss S, Haemmerle H, Zrenner E: Electrical multisite stimulation of the isolated chicken retina. Vision Res 40, 1785-1795 (2000)
  18. O265 Wilhelm H, Neitzel J, Wilhelm B, Beuel S, Lüdtke H, Kretschmann U, Zrenner E: Pupil perimetry using M-sequence stimulation technique. Invest Ophth Vis Sci 41, 1229-1238 (2000)
  19. O264 Werner A, Sharpe LT, Zrenner E: Asymmetries in the time-course of chromatic adaptation and the significance of contrast. Vision Res 40, 1101-1113 (2000)
  20. O263 Sobottka B, Schlote T, Besch D, Djelebova T, Wilhelm H, Zrenner E: [Carcinoma-associated retinopathy: a review with clinical examples]. German. Klin Monatsbl Augenh 216, 17-24 (2000)
  21. O262 Besch D, Wissinger B, Zrenner E, Leo-Kottler B: [A case of Leber optic neuropathy with a new point mutation in the cytochrome b gene]. German. Ophthalmologe 97, 27-32 (2000)
  22. O261 Schaeffel F, Zrenner E: [No correlation between night light and myopia in children after all?]. German. Klin Monbl Augenheilkd. 2000 Nov;217(5):255-6. (2000)

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1999

  1. O260 Schubert M B, Stelzle M, Graf M, Stett A, Nisch W. Graf H.G, Hämmerle H,Gabel V P, Höfflinger B, Zrenner E: Subretinal implants for the recovery of vision.International Conference on Systems 1999 IEEE Proceedings
  2. O259 Erb C, Nicaeus T, Adler M, Isensee J, Zrenner E, Thiel HJ: Colour vision disturbances in chronic smokers. Graefes Arch Clin Exp Ophthalmology 237, 377-380 (1999)
  3. O258 Zrenner E : Die Kuba-Therapie - Immer wieder Hoffnung? Stellungnahme von Prof. Zrenner. Retina Aktuell 4 (99), 22-23 (1999)
  4. O257 Marmor MF, Zrenner E: Standard for clinical electroretinography (1999 update). Doc Ophthalmol 97, 143-156 (1999)
  5. O256 Schlosshauer B, Hoff A, Guenther E, Zrenner E, Haemmerle H: Towards a retina prosthesis model: neurons on microphotodiode arrays in vitro. Biomedical Microdevices 2, 61-72 (1999)
  6. O255 Kretschmann U, Stilling R, Rüther K, Zrenner E: Familial macular cone dystrophy: diagnostic value of multifocal ERG and two-color threshold perimetry. Graefes Arch Clin Exp Ophthalmol. 237, 429-432 (1999)
  7. O254 Erb C, Ulrich A, Adler M, Flammer J, Zrenner E: Influence of illumination on results of the hue-discrimination test, Roth 28-Hue desaturated. Neuro-ophthalmology 22, 33-36 (1999)
  8. O253 Guenther E, Troeger B, Schlosshauer B, Zrenner E: Long-term survival of retinal cell cultures on retinal implant materials. Vision Res 39, 3988-3994 (1999)
  9. O252 Heine S, Ruether K, Isensee J, Zrenner E: [Clinical significance of objective vision assessment using visually evoked cortical potentials induced by rapid pattern sequences of different spatial frequency]. German. Klin Monatsbl Augenh 215, 175-181 (1999)
  10. O251 Tornow RP, Stilling R, Zrenner E: Scanning laser densitometry and color perimetry demonstrate reduced photopigment density and sensitivity in two patients with retinal degeneration. Vision Res 39, 3630-3641 (1999)
  11. O250 Besch D, Leo-Kottler B, Zrenner E, Wissinger B: Leber's hereditary optic neuropathy: clinical and molecular genetic findings in a patient with a new mutation in the ND6 gene. Graefes Arch Clin Exp Ophthalmol 237, 745-752, (1999)
  12. O249 Kurtenbach A, Neu A, Zrenner E: A temporal deficit in juvenile diabetics. Graefes Arch Clin Exp Ophthalmol 237, 636-641 (1999)
  13. O248 Biel M, Seeliger M, Pfeifer A, Kohler K, Gerstner A, Ludwig A, Jaissle G, Fauser S, Zrenner E, Hofmann F: Selective loss of cone function in mice lacking the cyvlic nucleotide-gated channel CNG3. Proc Natl Acad Sci 96, 7553-7557 (1999)
  14. O247 Hettesheimer H, Erb C, Schiefer U, Zrenner E: [White-noise field campimetry in HIV+patients]. German. Der Ophthalmologe 96 (7), 437-442 (1999)
  15. O246 Zrenner E: In der Existenz bedroht. Die prekäre Situation der Ambulanzen an den Hochschulklinika. Forschung & Lehre 7, 360-363 (1999)
  16. O245 Wolf S, Sharpe LT, Schmidt H-JA, Knau H, Weitz S, Kioschis P, Poustka A, Zrenner E, Lichter P, Wissinger B: Direct visual resolution of gene copy number in the human photopigment gene array. Invest Ophthalmol & Vis Sci 40 (7), 1585-1589 (1999)
  17. O244 Biesalski HK, Frank J, Beck SC, Heinrich F, Illek B, Reifen R, Gollnik H, Seeliger MW, Wissinger B, Zrenner E: Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein. Am J Clin Nutr 69, 931-937 (1999)
  18. O243 Zrenner E, Stett A, Weiss S, Aramant RB, Guenther E, Kohler K, Miliczek K-D, Seiler MJ, Haemmerle H: Can subretinal microphotodiodes successfully replace degenerated photoreceptors? Vision Research 39, 2555-2567 (1999)
  19. O242 Zrenner E, Gabel V-P, Haemmerle H, Hoefflinger B: Reply to the letter of drs. Chow and Peachey: the subretinal microphotodiode array retinal prosthesis II. Ophthalmic Res 31, pp. 31 (1999)
  20. O241 Baehr W, Spekreijse H, Zrenner E: Editorial. Retinal development, degeneration and functional restitution. Vision Res 39, 2439-2440 (1999)
  21. O240 Guenther E, Schmid S, Reiff D, Zrenner E: Maturation of intrinsic membrane properties in rat retinal ganglion cells. Vision Res 39, 2477-2484 (1999)
  22. O239 Seeliger M, Pfister M, Gendo K, Paasch S, Apfelstedt-Sylla E, Plinkert P, Zenner H-P, Zrenner E: Comparative study of visual, auditory, and olfactory function in Usher syndrome. Graefes Arch Clin Exp Ophthalmol 237, 301-307 (1999)
  23. O238 Zrenner E: No cause for alarm over retinal side-effects of sildenafil. The Lancet 353, 340-341 (1999)
  24. O237 Janecke A, Meins M, Sadeghi M, Grundmann K, Apfelstedt-Sylla E, Zrenner E, Rosenberg T, Gal A: Twelve novel myosin VIIA mutations in 34 patients with Usher syndrome type I: confirmation of genetic heterogeneity. Human Mutation 13, 133-140 (1999)
  25. O236 Kurtenbach A, Schiefer U, Neu A, Zrenner E: Development of brightness matching and colour vision deficits in juvenile diabetics. Vision Research 39 (6), 1221-1229 (1999)
  26. O235 Friedburg C, Serey L, Sharpe LT, Trauzettel-Klosinski S, Zrenner E: Evaluation of the Night Vision Spectacles on patients with impaired night vision. Graefes Arch Clin Exp Ophthalmol 237 (2), 125-136 (1999)
  27. O234 Kurtenbach A, Schiefer U, Neu A, Zrenner E: Preretinopic changes in the colour vision of juvenile diabetics. Br J Ophthalmol 83 (1), 43-46 (1999)
  28. O233 Seeliger MW, Biesalski HK, Wissinger B, Gollnik H, Gielen S, Frank J, Beck S, Zrenner E: Phenotype in retinol deficiency due to a hereditary defect in retinol binding protein synthesis. Invest Ophthalmol & Vis Sci 40 (1), 3-11 (1999)
  29. O232 Schaeffel F, Zrenner E:.[Myopia due to bedroom lighting in young children?]. German. Klin Monbl Augenheilkd. 1999 Sep;215(3):145-6. (1999)

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1998

  1. O231 Leo-Kottler B, Klein R, Berg PA, Zrenner E: Ocular symptoms in association with antiphospholipid antibodies. Graef Arch Clin Exp 236, 658-668 (1998)
  2. O230 Kohl S, Giddings I, Besch D, Apfelstedt-Sylla E, Zrenner E, Wissinger B: The role of the peripherin/RDS gene in retinal dystrophies. Acta Anatomica 162, 75-84 (1998)
  3. O229 Zrenner E, Lütjen-Drecoll E: Preface. Hereditary Retinal Degeneration. Acta Anatomica 162, 2-3 (1998)
  4. O228 Zrenner E: Die Einnahme von Viagra kann zu Beeinträchtigungen des Farbsinns führen. Wie sind die Sehstörungen zu werten? Ophthalmologische Nachrichten 10, pp. 17 (1998)
  5. O227 Zrenner E: Zelluläre Mechanismen sensorischer Prozesse und neuronaler Interaktionen. Neuroforum 3, pp. 253 (1998)
  6. O226 Burkhard C, Wilhelm H, Zrenner E: [Indications of invasive therapy of splenoid bone meningiomas - a case-report]. German. Z Prakt Augenheilkd 19, 337-340 (1998)
  7. O225 Heine S, Wilhelm H, Zrenner E: Karotisdissektion mit Horner-Syndrom nach chiropraktischer Behandlung der Halswirbelsäule. Z Prakt Augenheilkd 19, 333-336 (1998)
  8. O224 Zrenner E: Einnahme von Viagra bei Netzhautdegenerationen. Retina Aktuell 3 (69), 24-26 (1998)
  9. O223 Kohl S, Marx T, Giddings I, Jägle H, Jacobson SG, Apfelstedt-Sylla E, Zrenner E, Sharpe LT, Wissinger B: Total colourblindness is caused by mutations in the gene encoding the alpha-subunit of the cone photoreceptor cGMP-gated cation channel. Nature Genetics 19, 257-259 (1998)
  10. O222 Wissinger B, Jägle H, Kohl S, Broghammer M, Baumann B, Hanna DB, Hedels C, Apfelstedt-Sylla E, Randazzo G, Jacobson SG, Zrenner E, Sharpe LT: Human rod monochromacy: linkage analysis and mapping of a cone photoreceptor expressed candidate gene on chromosome 2q11. Genomics 51, 325-331 (1998)
  11. O221 Erb C, Adler M, Stübiger N, Wohlrab M, Zrenner E, Thiel H-J: Colour Vision in normal subjects tested by the colour arrangement test 'Roth 28-hue desaturated'. Vision Research 38, 3467-3471 (1998)
  12. O220 Zrenner E, Weiss S: Möglichkeiten und Perspektiven subretinaler Retinaimplantate. Med-report 26 (22), pp. 12 (1998)
  13. O219 Kretschmann U, Seeliger M, Ruether K, Usui T, Zrenner E: Spatial cone activity distribution in diseases of the posterior pole determined by multifocal electroretinography. Vision Research 38, 3817-3828 (1998)
  14. O218 Leo-Kottler B, Christ-Adler M, Wissinger B, Zrenner E: [Diagnostic error in Leber's optic neuropathy. Value of clinical and molecular genetic studies]. German. Der Ophthalmologe 95, 549-554 (1998)
  15. O217 Usui T, Kremers J, Sharpe LT, Zrenner E: Flicker cone electroretinogram in dichromats and trichromats. Vision Research 38, 3391-3396 (1998)
  16. O216 Zrenner E: Antrittsrede in der Heidelberger Akademie der Wissenschaften. Jahrbuch Der Heidelberger Akademie Der Wissenschaften für 1997, 107-112 (1998)
  17. O215 Strom TM, Nyakatura G, Apfelstedt-Sylla E, Hellebrand H, Lorenz B, Weber BHF, Wutz K, Gutwillinger N, Rüther K, Drescher B, Sauer C, Zrenner E, Meitinger T, Rosenthal A, Meindl A: An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness. Nature Genetics 19, 260-263 (1998)
  18. O214 Zrenner E: [How should viagra-induced vision disorders - especially retinal degeneration - be evaluated?]. German. Klin Mbl Augenheilk 212 (6), A12-A13 (1998)
  19. O213 Usui T, Kremers J, Sharpe LT, Zrenner E: Response phase of the flicker electroretinogram (ERG) is influenced by cone excitation strength. Vision Research 38, 3247-3251 (1998)
  20. O212 Kretschmann U, Tornow R-P, Zrenner E: Multifocal ERG reveals long distance effects of a local bleach in the retina. Vision Research 38(11), 1567-1571 (1998)
  21. O211 Zrenner E, Gabel V-P, Haemmerle H, Hoefflinger B, Schubert M: Subretinal Implants. Ophthalmic Res 30, 197-198 (1998)
  22. O210 Seeliger MW, Kretschmann UH, Apfelstedt-Sylla E, Zrenner E: Implicit time topography of multifocal electroretinograms. Invest Ophthalmol & Visl Sci 39 (5), 718-723 (1998)
  23. O209 Rüther K, Ehlich P, Philipp A, Eckstein A, Zrenner E: Prognostic value of pattern electroretinogram in cases of tumors affecting the optic pathway. Graefes Archive Clin Exp Ophthalm 236, 259-263 (1998)
  24. O208 Kretschmann U, Schlote T, Stübiger N, Gendo K, Hipp E, Zrenner E: [Multifocal electroretinography in acquired macular dysfunction]. German. Klin Mbl Augenheilk 212, 93-100 (1998)
  25. O207 Kretschmann U, Apfelstedt-Sylla E, Zrenner E: Morbus Stargardt-Fundus flavimaculatus (Stargardt's macular dystrophy - Fundus flavimaculatus). Z Prakt Augenheilk 19, 89-96 (1998)
  26. O206 Kretschmann U, Seeliger MW, Ruether K, Apfelstedt-Sylla E, Zrenner E: Multifocal electroretinography in patients with Stargardt's macular dystrophy. Br J Ophthalmol 82 (3), 267-275 (1998)
  27. O205 Kretschmann U, Gendo K, Wilhelm H, Schiefer U, Hettesheimer H, Zrenner E: [Objective assessment of visual field defects using multifocal electroretinography]. German. Klin Mbl Augenheilk 212, 40-49 (1998)
  28. O204 Seeliger M, Kretschmann U, Apfelstedt-Sylla E, Rüther K, Zrenner E: Multifocal electroretinography in retinitis pigmentosa. Am J Ophthalmol 125 (2), 214-226 (1998)
  29. O203 Friedburg C, Sharpe LT, Beuel S, Zrenner E: A computer-controlled system for measuring dark adaptation and other psychophysical functions. Graefes Arch Clin Exp Ophthalm 236, 31-40 (1998)

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1997

  1. O202 Ehlich P, Sadowski B, Zrenner E: ["Oligocone" trichromasy, a rare form of incomplete achromatopsia]. German. Ophthalmologe 94 (11), 801-806 (1997)
  2. O201 Wissinger B, Müller F, Weyand I, Schuffenhauser S, Thanos S, Kaupp UB, Zrenner E: Cloning, chromosomal localization and functional expression of the gene encoding the alpha-subunit of the cGMP-gated channel in human cone photoreceptors. European Journal of Neuroscience 9, 2512-2521 (1997)
  3. O200 Bayer AU, Thiel H-J, Zrenner E, Dichgans J, Kuehn M, PaulusW, Schmidt D: Color vision tests for early detection of antiepleptic drug toxicity. Neurology 48, 1394-1397 (1997)
  4. O199 Krastel H, Zrenner E, Eggers I, Wetzel C, Nimsgern C, Auffarth G, Sadowski B, Trauzettel-Klosinski S, Rüther K: Richtlinien zur Anpassung von Kantenfiltern. Zur Umsetzung und Anwendung der Heil- und Hilfsmittelrichtlinien. Der Augenarzt 5, 155-159 (1997)
  5. O198 Kohler K, Günther E, Zrenner E: [Animal models for retinitis pigmentosa research]. German. Klin Mbl Augenheilk 211, 84-93 (1997)
  6. O197 Kohl S, Christ-Adler M, Apfelstedt-Sylla E, Kellner U, Eckstein A, Zrenner E, Wissinger B: RDS/peripherin gene mutations are frequent causes of central retinal dystrophies. Journal Of Medical Genetics 34 (8), 620-626 (1997)
  7. O196 Kohler K, Lilienthal H, Günther E, Winneke G, Zrenner E: Persistent decrease of the dopamine-synthesizing enzyme tyrosine hydroxylase in the rhesus monkey retina after chronic lead exposure. Neurotoxicology 18 (3), 623-632 (1997)
  8. O195 Marlhens F, Bareil C, Griffoin J-M, Zrenner E, Amalric P, Eliaou C, Liu S-Y, Harris E, Redmond TM, Arnaud B, Claustres M, Hamel CP: Mutations in RPE65 cause Leber's congenital amaurosis. Nature Genetics 17, 139-141 (1997)
  9. O194 Kretschmann U, Usui T, Ruether K, Zrenner E: Electroretinographic campimetry in a patient with crystalline retinopathy. German J Ophthalmol 5, 399-403 (1997)
  10. O193 Kretschmann U, Gendo K, Seeliger M, Zrenner E: Multifocal ERG recording by the VERIS technique and its clinical applications (Wiedemann/Kohen (eds): Macular and Retinal Diseases). Dev Ophthalmol 29, 8-14 (1997)
  11. O192 Zrenner E: Chancen für junge Ärzte. Deutsches Ärzteblatt 94 (39), 2012-2013 (1997)
  12. O191 Jurklies B, Zrenner E, Wessing A: [Retinitis pigmentosa--clinical, genetic and pathophysiologic aspects]. German. Klin Mbl Augenheilk 210, 1-18 (1997)
  13. O190 Zrenner E, Miliczek K-D, Gabel VP, Graf HG, Günther E, Hämmerle H, Höfflinger B, Kohler K, Nisch W, Schubert M, Stett A, Weiss S: The development of subretinal microphotodiodes for replacement of degenerated photoreceptors. Ophthalmic Res. 29 (5), 269-280, (1997)
  14. O189 Seeliger M, Rüther K, Apfelstedt-Sylla, Schlote W, Wohlrab M, Zrenner E: [Juvenile neuronal ceroid lipofuscinosis (Batten-Mayou) disease. Ophthalmologic diagnosis and findings]. German. Der Ophthalmologe 94, 557-562 (1997)
  15. O188 Kremers J, Weiss S, Zrenner E: Temporal properties of marmoset lateral geniculate cells. Vision Res. 37 (19), 2649-2660 (1997)
  16. O187 Kremmer S, Eckstein A, Gal A, Apfelstedt-Sylla E, Wedemann H, Rüther K, Zrenner E: Ocular findings in patients with autosomal dominant retinitis pigmentosa and Cys110Phe, Arg135Gly, and Gln344stop mutations of rhodopsin. Graefes Arch Clin Exp Ophthalm 235, 575-583 (1997)
  17. O186 Tornow P-R, Beuel S, Zrenner E: Modifying a Rodenstock scanning laser ophthalmoscope for imaging densitometry. Applied Optics 36 (22), 5621-5629 (1997)
  18. O185 Günther E, Hewig B, Zrenner E, Kohler K: Angiotensin II-induced inhibition and facilitation of calcium current subtypes in rat retinal ganglion cells. Neuroscience Letters 231, 71-74 (1997)
  19. O184 Sadowski B, Zrenner E: Cone and rod function in cone degenerations. Vision Research 37 (16), 2303-2314 (1997)
  20. O183 Wissinger B, Besch D, Baumann B, Fauser S, Christ-Adler M, Jurklies B, Zrenner E, Leo-Kottler B: Mutation analysis of the ND6 gene in patients with Lebers hereditary optic neuropathy. Biochemical and Biophysical Research Communication 234 (2), 511-515 (1997)
  21. O182 Felbor U, Doepner D, Schneider U, Zrenner E, Weber BHF: Evaluation of the gene encoding the tissue inhibitor of metalloproteinases-3 in various maculopathies. Invest Ophthalmol Vis Sci 38 (6), 1054-1059 (1997)
  22. O181 Eckstein AK, Reichenbach A, Jacobi P, Weber P, Gregor M, Zrenner E: Hepatic retinopathia. Changes in retinal function. Vision Research 37 (12), 1699-1706 (1997)
  23. O180 van de Hurk JAJM, Hendriks W, van de Pol DJR, Oerlemans F, Jaissle G, Rüther K, Kohler K, Hartmann J, Zrenner E, van Bokhoven H, Wieringa B, Ropers H-H, Cremers FPM: Mouse choroideremia gene mutation causes photoreceptor cell degeneration and is not transmitted through the female germline. Human Molecular Genetics 6 (6), 851-858 (1997)
  24. O179 Kohler K, Wheeler-Schilling T, Jurklies B, Günther E, Zrenner E: Angiotensin II in the rabbit retina. Visual Neuroscience 14, 63-71 (1997)
  25. O178 Zrenner E: Die Chancen für Wissenschaftler sind gut. Ophthalmologische Nachrichten 4, pp. 8 (1997)
  26. O177 Ruether K, van de Pol D, Jaissle G, Berger W, Tornow R-P, Zrenner E: Retinoschisislike alterations in the mouse eye caused by gene targeting of the Norrie disease gene. Invest Ophthalmol & Vis Sci 38 (3), 710-718 (1997)
  27. O176 Schaeffel F, Zrenner E: Steuerung des Augenlängenwachstums durch Sehen.Tierexperimentelle Befunde zur Kurzsichtigkeit und ihre möglichen therapeutischen Konsequenzen. Deutsches Ärzteblatt 94(17), 1121-1128 und (49) 3357-3359(1997)
  28. O175 Kurtenbach A, Rüttiger L, Kaiser PK, Zrenner E: Influence of luminance flicker and purity on heterochromatic brightness matching and hue discrimination: a postreceptoral opponent process. Vision Res. 37 (6), 721-728 (1997)
  29. O174 Gal A, Apfelstedt-Sylla E, Janecke AR, Zrenner E: Rhodopsin mutations in inherited retinal dystrophies and dysfunctions. Progress in Retinal Eye Research 16 (1), 51-79 (1997)

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1996

  1. O173 Kretschman U, Rüther K, Usui T, Zrenner E: ERG campimetry using a multi-input stimulation technique for mapping of retinal function in the central visual field. Ophthalmic Res 28, 303-311 (1996)
  2. O172 Jacobi PC, Osswald H, Zrenner E: Bradykinin receptor inhibition affects the rod b-wave in the cat electroretinogram. Vision Res 36 (23), 3843-3849 (1996)
  3. O171 Schiefer U, Gisolf AC, Kirsch J, Selbmann H-K, Zrenner E: [Noise field screening. Results of a television field study for detection of visual field defects]. German. Der Ophthalmologe 93, 604-616 (1996)
  4. O170 Rüther K, Zrenner E: Factors that influence the increase in the electroretinogram 30-Hz flicker amplitude during light adaptation. German J Ophthalmol 5, 285-288 (1996)
  5. O169 Marmor MF, Holder GE, Porciatti V, Trick GL, Zrenner E: Guidelines for basic pattern electroretinography. Recommendations by the International Society for Clinical Electrophysiology of Vision. Documenta Ophthalmologica 91, 291-298 (1996)
  6. O168 Fink W, Frohn A, Schiefer U, Schmid EW, Wendelstein N, Zrenner E: [Visual image in high ametropia. Computer-assisted simulation with optic ray calculation]. German. Klin Mbl Augenheilk 208, 472-476 (1996)
  7. O167 Weber BHF, Sander S, Kopp C, Walker D, Eckstein A, Wissinger B, Zrenner E, Grimm T: Analysis of 21 Stargardt's disease families confirms a major locus on chromosome 1p with evidence for non-allelic heterogeneity in a minority of cases. British J Ophthalmol 80 (8), 745-749 (1996)
  8. O166 Leo-Kottler B, Christ-Adler M, Baumann B, Zrenner E, Wissinger B: Leber's hereditary optic neuropathy: clinical and molecular genetic results obtained in a family with a new point mutation at nucleotide position 14498 in the ND 6 gene. German J Ophthalmol 5, 233-240 (1996)
  9. O165 Trauzettel-Klosinski S, Diener HC, Dietz K, Zrenner E: The effect of oral prednisolone on visual evoked potential latencies in acute optic neuritis monitored in a prospective, randomized, controlled study. Documenta Ophthalmologica 91, 165-179 (1996)
  10. O164 Meindl A, Dry K, Herrmann K, Manson E, Ciccodicola A, Edgar A, Carvalho MRS, Achatz H, Hellebrand H, Lennon A, Migliaccio C, Porter K, Zrenner E, Bird A, Jay M, Lorenz B, Wittwer B, D'Urso M, Meitinger T, Wright A: A gene (RPGR)with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3). Nature Genetics 13, 35-42 (1996)
  11. O163 Kremmer S, Schiefer U, Wilhelm H, Zrenner E: [Mobilization of intraocular foreign bodies by magnetic resonance tomography]. German. Klin Mbl Augenheilk 208, 201-202 (1996)

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1995

  1. O157 Kellner U, Sadowski B, Zrenner E, Foerster H:
    Selective Cone Dystrophy with Protan Genotype. Invest Ophthalmol & Vis Sci 36 (12), 2381-2387 (1995)
  2. O156 Zrenner E, Biesalski Otto S, Rüther K:
    Vitamin A. Empfehlungen zur Vitamin-A-Einnahme mit dem Ziel, den Krankheitsverlauf bei Retinitis Pigmentosa zu verlangsamen. DRPV-Sonderdruck 105 (4) (1995)
  3. O155 Sadowski B, Altenmüller E, Zrenner E:
    Electrophysiological and psychophysical examination in patients with optic nerve compression. Neuro-opthalmology 15 (5), 223-231 (1995)
  4. O154 Rüther K, Banhart F, Kremmer S, Apfelstedt-Sylla E, Zrenner E:
    Sozial-ophthalmologische Aspekte bei Retinitis Pigmentosa. Ophthalmologe 92, 704-707 (1995)
  5. O153 Kohler K, Zrenner E, Weiler R:
    Ethambutol Alters Spinule-type Synaptic Connections and Induces Morphologic Alterations in the Cone Pedicles of the Fish Retina. Invest Ophthalmol & Vis Sci 36 (6), 1046-1055 (1995)
  6. O152 Marmor MF, Zrenner E:
    Standard for clinical electroretinography (1994 update). Documenta Ophthalmologica 89, 199-210 (1995)
  7. O151 Schmitz Y, Kohler K, Zrenner E:
    Evidence for calcium/calmodulin dependence of spinule retraction in retinal horizontal cells. Visual Neuroscience 12, 413-424 (1995)
  8. O150 Jurklies B, Eckstein A, Jacobi Ph Kohler K, Risler T, Zrenner E:
    The renin-angiotensin system - a possible neuromodulator in the human retina?. German J Ophthalmol 4, 144-150 (1995)
  9. O149 Schaeffel F, Bartmann M, Hagel G, Zrenner E:
    Studies on the Role of the Retinal Dopamine/Melatonin System in Experimental Refractive Errors in Chickens. Vision Res 35 (9), 1247-1264 (1995)
  10. O148 Leo-Kottler B, Christ-Adler M, Reck B, Wissinger B und Zrenner E:
    Korrelation klinischer und molekulargenetischer Befunde bei Leber'scher Opticusneuropathie (LHON). Ophthalmologe 92, 86-92 (1995)
  11. O147 Bayer A, Thiel H-J, Zrenner E, Paulus W, Ried S und Schmidt D:
    Empfindliche sinnesphysiologische Testmethoden für okuläre Nebenwirkungen von Medikamenten am Beispiel verschiedener Antiepileptika. Ophthalmologe 92, 182-190 (1995)
  12. O146 Schiefer U, Pfau U, Selbmann H-K, Wilhelm H und Zrenner E:
    Sensitivität und Spezifizität der Rauschfeldkampimetrie. Ophthalmologe 92, 156-167 (1995)
  13. O145 Apfelstedt-Sylla E, Theischen M, Rüther K, Wedemann H, Gal A, Zrenner E:
    Extensive intrafamilial phenotypic variation among patients with autosomal dominant retinal dystrophy and mutations in the human RDS/peripherin gene. Br J Ophthalmol 79, 28-34 (1995)
  14. O144 Schiefer U, Kurtenbach A, Braun E, Kraus W, Zrenner E:
    Centrally tinted contact lenses. A useful visual aid for patients with achromatopsia. German J Ophthalmol 4, 52-56 (1995)

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1994

  1. O146 Sadowski B, Zrenner E: [Differential diagnosis of cone dystrophies]. German. Der Ophthalmologe 91, 719-729 (1994)
  2. O145 Rüther K, Sharpe LT, Zrenner E: Dual rod pathways in complete achromatopsia. German J Ophthalmol 3, 433-439 (1994)
  3. O144 Günther E, Wilsch V, Zrenner E: Inhibitory action of haloperidol, spiperone and SCH23390 on calcium currents in rat retinal ganglion cells. Neuroreport 5 (11), 1373-1376 (1994)
  4. O143 Trauzettel-Klosinski S, Teschner C, Tornow R-P, Zrenner E: Die Bedeutung des zentralen Gesichtsfeldes für die Lesefähigkeit und Rehabilitation Sehbehinderter. Spektrum Augenheilkd 8 (3), 128-134 (1994)
  5. O142 Zrenner E: Optikusneuritis bei zwei Vettern - Unbedingt das Rauchen verbieten. Medical Tribune 33, pp. 2 (1994)
  6. O141 Banhart F, Klaeren H, Zrenner E: Eine graphische Oberfläche für die Generierung von Datenbankanfragen basierend auf einem objektorientierten Datenmodell. Gi Datenbank-Rundbrief 13, 64-66 (1994)
  7. O140 Bartmann ML, Schaeffel F, Hagel G, Zrenner E: Constant light affects retinal dopamine levels and blocks deprivation myopia but not lens-induced refractive errors in chickens. Visual Neuroscience 11, 199-208 (1994)
  8. O139 Jacobi PC, Jurklies B, Kohler K, Zrenner E: [Experimental studies of the significance of the renin-angiotensin system in the retina. A review]. German. Klin Mbl Augenheilkd. 204, 527-534 (1994)
  9. O138 Fuchs S, Kranich H, Denton MJ, Zrenner E, Bhattacharya SS, Humphries P, Gal A: Three novel rhodopsin mutations (C110F, L131P, A164V) in patients with autosomal dominant retinitis pigmentosa. Human Molecular Genetics 3 (7), pp. 1203 (1994)
  10. O137 Zrenner E: Krankenversorgung, Forschung und Lehre - Zur Zusammenarbeit zwischen Klinikumsvorstand und Fakultät. Forschung & Lehre 8, 328-331 (1994)
  11. O136 Trauzettel-Klosinski S, Teschner C, Tornow RP, Zrenner E: Reading strategies in normal subjects and in patients with macular scotoma-assessed by two new methods of registration. Neuro-Ophthalmology 14 (1), 15-30 (1994)
  12. O135 Grüning G, Millan JM, Meins M, Beneyto M, Caballero M, Apfelstedt-Sylla E, Bosch R, Zrenner E: Mutations in the human peripherin/RDS gene associated with autosomal dominant retinitis pigmentosa. Human Mutation 3, 321-323 (1994)
  13. O134 Schaeffel F, Hagel G, Bartmann M, Kohler K, Zrenner E: 6-Hydroxy dopamine does not affect lens-induced refractive errors but suppresses depriviation myopia. Vision Res 34 (2), 143-149 (1994)
  14. O133 Jacobi P, Oswald H, Jurklies B, Zrenner E: Neuromodulatory effects of the renin-angiotensin system on the cat electroretinogram. Invest Ophthalmol & Vis Sci 35 (3), 973-980 (1994)
  15. O132 Guenther E, Schmid S, Grantyn R, Zrenner E: In vitro identification of retinal ganglion cells in culture without the need of dye labeling. Journal of Neuroscience Methods 51, 177-181 (1994)
  16. O131 Eckstein A, Eckstein S, Rüther K, Zrenner E: [Electroretinography study of unanesthetized young children]. German. Klin Mbl Augenheilk 204, 105-110 (1994)
  17. O130 Rüther K, Eisenmann D, Zrenner E, Jacobi KW: [Effect of diffractive multi-focal lenses on contrast vision, glare sensitivity and color vision]. German. Klin Mbl Augenheilk 204, 14-19 (1994)
  18. O129 Jurklies B, Kohler K, Eikermann J, Zrenner E: Angiotensin II-like immunoreactivity in the retina of some mammalian species. German J Ophthalmol 3, 37-42 (1994)
  19. O128 Kurtenbach A, Wagner U, Neu A, Schiefer U, Ranke MB, Zrenner E: Brightness matching and colour discrimination in young diabetics without retinopathy. Vision Res 34 (1), 115-222 (1994)

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1993

  1. O137 Schiefer U, Rathmachers B, Schmid EW, Aulhorn E, Zrenner E:
    Visuelle Beeinträchtigung von Fahrzeugführern durch einen Front-Fotoblitz unter mesopischen Bedingungen. Klin Mbl Augenheilk 202, 116-125 (1993)
  2. O135 Zrenner E:
    Ungenügende Versorgung Sehbehinderter in Deutschland. Z Prakt Augenheilkd 14, 215-216 (1993)
  3. O130 Jacobi PC, Miliczek K-D, Zrenner E:
    Experiences with the international standard for clinical electroretinography: normative values for clinical practice, interindividual and intraindividual variations and possible extensions. Documenta Ophthalmologica 85, 95-114 (1993)
  4. O120 Paulus W, Schwarz G, Werner A, Lange H, Bayer A, Hofschuster M, Müller N, Zrenner E: Impairment of Retinal increment thresholds in Huntington's disease. Ann Neurol 34, 574-578 (1993)
  5. O119 Kellner U, Zrenner E, Sadowski B, Foerster MH:
    Enhanced S cone sensitivity syndrome: Long-term follow-up, electrophysiological and psychophysical findings. Clin. Vision Sci. Vol. 8, No 8 (5), 425-434 (1993)
  6. O118 Rüther K, Apfelstedt-Sylla E, Zrenner E:
    Clinical findings in patients with congenital stationary night blindness of the Schubert-Bornschein type. German J Ophthalmol 2, 429-435 (1993)
  7. O116 Nathans J, Maumenee IH, Zrenner E, Sadowski B, Sharpe LT, Lewis RA, Hansen E, Rosenberg T, Schwartz M, Heckenlively JR, Traboulsi E, Klingaman R, Bech-Hansen NT, LaRoche GR, Pagon RA, Murphey WH, Weleber RG:
    Genetic Heterogeneity among Blue-Cone Monochromats. Am J Hum Genet 53, 987-1000 (1993)
  8. O115 Rüther K, Zrenner E:
    Entwicklungen in der ophthalmologischen Elektrophysiologie. Klin Mbl Augenheilk 202, 140-145 (1993)
  9. O113 Frederiksen JL, Larsson HBW, Paulus W, Zrenner E:
    Spectral sensitivity of visual evoked potentials elicited by shifting monochromatic checkerboard patterns. II. Patients with multiple sclerosis. Clin Vision Sci 8 (4), 375-383 (1993)
  10. O112 Schiefer U, Kolb M, Wilhelm H, Petersen D, Zrenner E, Harms H:
    Detection of homonymous visual field defects with flickering random dot pattern. Perimetry Update, Kugler Publications 1992/93, 243-251 (1993)
  11. O111 Wilhelm H, Grodd W, Schiefer U, Zrenner E:
    Uncommon chiasmal lesions: demyelinating disease, vasculitis, and cobalamin deficiency. German J Ophthalmol 2, 234-240 (1993)
  12. O110 Datum K-H, Kohler K, Zrenner E:
    Immunhistochemische Untersuchungen zur Rolle dopaminerger retinaler Zellen bei der neuronalen Helligkeitsanpassung. Klin Mbl Augenheilk 203, 59-69 (1993)
  13. O109 Apfelstedt-Sylla E, Kunisch M, Horn M, Rüther K, Gerding H, Gal A, Zrenner E:
    Ocular findings in a family with autosomal dominant retinitis pigmentosa and a frameshift mutation altering the carboxyl terminal sequence of rhodopsin. British Journal of Ophthalmology 77, 495-501 (1993)
  14. O107 Hockwin O, Zrenner E:
    Light damage to the eye. Karger Gazette, S. Karger AG, Basel, No. 56, 2-3 (1993)
  15. O106 Marmor MF, Zrenner E:
    Standard for clinical electro-oculography. Arch Ophthalmol 111, 601-604 (1993)
  16. O105 Guenther E, Zrenner E:
    The spectral sensitivity of dark- and light-adapted cat retinal ganglion cells. The Journal of Neuroscience 13 (4), 1543-1550 (1993)
  17. O104 Guenther E, Zrenner E:
    Differences in adaption between on- and off-centre ganglion cells and rod-mediated cone sensitization in cat retina. J Physiol 464, 613-627 (1993)
  18. O103 Ochsendorf FR, Runne U, Goerz G, Zrenner E:
    Chloroquin-Retinopathie: durch individuelle Tagesdosis vermeidbar. Dtsch Med Wschr 118, 1895-1898 (1993)
  19. O102 Zrenner E, Wilhelm H, Schiefer U:
    Differentialdiagnostische Strategien bei unklaren Sehstörungen. Ophthalmologe 90, 104-119 (1993)
  20. O101 Zrenner E:
    Neuro-Ophthalmologie: Eine Herausforderung für jeden Augenarzt. Ophthalmologe 90, 101-103 (1993)
  21. O91 Marmor MF, Zrenner E:
    Standard for clinical electro-oculography. International Society for Clinical Electrophysiology of Vision. Doc Ophthalmol 85:115-124 (1993)
  22. O99 Jacobi PhC, Rüther K, Miliczek K-D, Völker M, Zrenner E:
    Klinische Elektroretinographie: Standardprotokoll und Normwerte. Klin Mbl Augenheilk 202, 27-42 (1993)

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1992

  1. O104 den Hurk JA, van de Pol TJ, Molloy CM, Brunsmann F, Rüther K, Zrenner E, Pinckers AJ, Pawlowitzki IH, Bleeker-Wagemakers EM, Wieringa B, et al.: Detection and characterization of point mutations in the choroideremia candidate gene by PCR-SSCP analysis and direct DNA sequencing. Am J Hum Genet. 1992 Jun;50(6):1195-202. (1992)
  2. O103 Horn M, Humphries P, Kunisch M, Marchese C, Apfelstedt-Sylla E, Fugi L, Zrenner E, Kenna P, Gal A, Farrar J: Deletions in exon 5 of the human rhodopsin gene causing a shift in the reading frame and autosomal dominant retinitis pigmentosa. Hum Genet. 1992 Nov;90(3):255-7. (1992)
  3. O102 Zrenner E, Rüther K, Wilhelm H: Bildschirmwahl bei Computern und Fernsehlesegeräten. Rp Journal 47/48 (4/5), 36-42 (1992)
  4. O101 Apfelstedt-Sylla E, Kunisch M, Horn M, Rüther K, Gal A, Zrenner E: Diffuse loss of rod function in autosomal dominant retinitis pigmentosa with pro-347-leu mutation of rhodopsin. German J Ophthalmol 1, 319-327 (1992)
  5. O100 Wilhelm H, Ochsner H, Kopycziok E, Trauzettel-Klosinski S, Schiefer U, Zrenner E: Horner`s syndrome: a retrospective analysis of 90 cases and recommendations for clinical handling. German J Ophthalmol 1, 96-102 (1992)
  6. O99 Weitz CJ, Miyake Y, Shinzato K, Montag E, Zrenner E, Went LN, Nathans J: Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin. Am J Hum Genet 50, 498-507 (1992)
  7. O98 Li Xiao-Xin Schaeffel F, Kohler K, Zrenner E: Dose-dependent effects of 6-hydroxy dopamine on deprivation myopia, electroretinograms, and dopaminergic amacrine cells in chickens. Visual Neuroscience 9, 483-492 (1992)
  8. O97 Schaeffel F, Wilhelm H, Zrenner E: Inter-individual variability in the dynamics of natural accommodation in humans: relation to age and refractive errors. J Physiol 461, 301-320 (1992)
  9. O96 Rüther K, Zrenner E: Leitsympton Nachtblindheit (Nyctalopia as an indicating sign). Z Prakt Augenheilk 13, 419-428 (1992)
  10. O95 Zrenner E, Rüther K, Apfelstedt-Sylla E: [Retinitis pigmentosa. Clinical findings, results of molecular genetic techniques and research perspectives]. German. Der Ophthalmologe 89, 5-21 (1992)
  11. O94 Ochsner H, Hauser B, Zrenner E: ["Glare vision". II. Study of visual acuity of glare sensitive patients in increasing test field luminance]. German. Klin Mbl Augenheilk 200, 110-112 (1992)
  12. O93 Hauser B, Ochsner H, Zrenner E: ["Glare vision". I. Physiological principles of vision change with increased test field luminance]. German. Klin Mbl Augenheilk 200, 105-109 (1992)
  13. O92 Reitner A, Sharpe LT, Zrenner E: Wavelength discrimination as a function of field intensity, duration and size. Vision Res 32, 179-185 (1992)

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1991

  1. O91 Schneider T, Zrenner E: Effects of D-1 and D-2 dopamine antagonists on ERG and optic nerve response of the cat. Exp Eye Res 52, 425-430 (1991)
  2. O90 Rüther K, Gruben C von, Zrenner E: [Effect of cut off filters on contrast perception in retinitis pigmentosa]. German. Fortschr Ophthalmol 88, 829-832 (1991)
  3. O89 Datum KH, Zrenner E: Angiotensin-like immunoreactive cells in the chicken retina. Exp Eye Res 53, 157-165 (1991)
  4. O88 Rohrer B, Schaeffel F, Zrenner E: Longitudinal chromatic aberration and emmetropization: results from the chicken eye. J Physiol 449, 363-376 (1991)
  5. O87 Schaeffel F, Rohrer B, Lemmer T, Zrenner E: Diurnal control of rod function in the chicken. Visual Neuroscience 6, 641-653 (1991)
  6. O86 Ochsner H, Hauser B, Zrenner E: [Relation of visual acuity of test field luminance in glare sensitivity of various origin]. German. Fortschr Ophthalm 88, 549-553 (1991)
  7. O85 Schiefer U, Wilhelm H, Zrenner E, Aulhorn E: [Modification of refraction and visual noise perception by suction cup oculocompression]. German. Fortschr Ophthalmol 88, 522-529 (1991)
  8. O84 Stockman A, Sharpe LT, Zrenner E, Nordby K: Slow and fast pathways in the human rod visual system: electrophysiology and psychophysics. J Opt Soc Am 8, 1657-1665 (1991)
  9. O83 de Jong PTVM, Zrenner E, van Meel GJ, Keunen JEE, Van Norren D: Mizuo phenomenon in x-linked retinoschisis. Pathogenesis of the mizuo phenomenon. Arch Ophthalmol 109, 1104-1108 (1991)
  10. O82 Fahle M, Zrenner E: Visual Psychophysics. Current Opinion in Ophthamol 2, 717-728 (1991)
  11. O81 Ettelt B, Brandl H, Zrenner E, und Lund O-E: [Vision test device: possibilities and limits of LCD technique]. German. Fortschr Ophthalmol 88, 59-63 (1991)
  12. O80 Wolff-Kormann PG, Kormann BA, Riedel KG, Keller C, Miliczek KD, Zrenner E: [Ocular side effects of beta-pyridylcarbinol]. German. Fortschr Ophthalm 88, 857-860 (1991)
  13. O79 Reitner A, Sharpe LT, Zrenner E: Is colour vision possible with only rods and blue-sensitive cones? Nature 352, 798-800 (1991)

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1990

  1. O78 Zrenner E: [Light-induced damage to the eye]. German. Fortschr Ophthalmol (suppl)87, 41-51 (1990)
  2. O77 Günther E, Zrenner E: Rod and cone contribution to adaptation processes in cat retinal ganglion cells. Doc Ophthalmol 75, 83-95 (1990)
  3. O76 Marx R, Zrenner E: Sensitivity distribution in the central and midperipheral visual field determined by pattern electroretinography and harmonic analysis. Doc Ophthalmol 73, 347-357 (1990)
  4. O75 Scheiffarth OF, Zrenner E, Disko R, Stefani FH, Brabänder B: Intraocular in vivo immunofluorescence. A new technique for visualizing structures of the ocular fundus. Invest Ophthalmol Vis Sci 31 (2), 272-276 (1990)

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1989

  1. O74 Kau T, Zrenner E, Boergen KP: [Recording of visual evoked potentials in infants: characteristics and optimization of the method]. German. Fortschr Ophthalmol 86, 497-501 (1989)
  2. O73 Zrenner E, Endres W, Lorenz B: Therapiemöglichkeiten bei Atrophia gyrata? Klin Mbl Augenheilk 195, 109-110 (1989)
  3. O72 Nasemann J, Zrenner E, Riedel KG: Recovery after severe ethambutol intoxication-psychophysical and electrophysiological correlations. Doc Ophthalmol 71, 279-292 (1989)
  4. O71 Marmor MF, Arden GB, Nilsson S-E, Zrenner E: International Standardization Committee. At last. A standard electroretinography protocol. Standard for clinical electroretinography. Arch Ophthalmol 107, 813-819 (1989)
  5. O70 Reitner A, Zrenner E: A computer-controlled system for clinically testing wavelength discrimination. Perception 18, 546-547 (1989)
  6. O69 Schneider T, Dahlheim P, Zrenner E: [Animal experiment studies of the ocular toxicity of cardiac glycosides]. German. Fortschr Ophthalmol 86, 751-755 (1989)
  7. O68 Hess RF, Mullen KT, Zrenner E: Human photopic vision with only short wavelength cones: post-receptoral properties. J Physiol 417, 151-172 (1989)
  8. O67 Hess RF, Mullen KT, Sharpe LT, Zrenner E: The photoreceptors in atypical achromatopsia. J Physiol 417, 123-149 (1989)
  9. O66 Meitinger T, Fraser NA, Lorenz B, Zrenner E, Murken J, Craig IW: Linkage of x-linked retinits pigmentosa to the hypervariable DNA marker M27ß (DXS255). Hum Gen 81, 283-286 (1989)

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1988

  1. O65 Nasemann J, Dahlheim P, Zrenner E: [Differential diagnosis of acute retinal pigment epitheliitis]. German. Fortschr Ophthalmol 85, 705-708 (1988)
  2. O64 Ulbig M, Zrenner E, Schneider T: [Functional and morphologic variations in fundus flavimaculatus]. German. Fortschr Ophthalmol 85, 312-316 (1988)
  3. O63 Baker CL, Hess RF, Olsen BT, Zrenner E: Current source density analysis of linear and non-linear components of the primate electroretinogram. J Physiol 407, 155-176 (1988)
  4. O62 Scheiffarth OF, Zrenner E, Disko R, Stefani FH, Brabänder B: [Intraocular in vivo immunofluorescence]. German. Fortschr Ophthalmol 85, 716-718 (1988)
  5. O61 Hajek A, Zrenner E: [Improved objective visual assessment with visual evoked cortical potentials by rapid pattern stimuli sequences of different spatial frequency]. German. Fortschr Ophthalmol 85, 550-554 (1988)
  6. O60 Zrenner E, Magnussen S, Lorenz B: [Blue cone monochromasia: diagnosis, genetic counseling and optical aids]. German. Klin Mbl Augenheilk 193, 510-517 (1988)
  7. O59 Dahlheim P, Schneider T, Reiter W, Zrenner E: [Angiotensin I converting enzyme: distribution of activity in the eye and neurophysiologic effect on retinal function]. German. Fortschr Ophthalmol 85, 709-715 (1988)
  8. O58 Zrenner E, Nelson R: Spatial characteristics of scotopic threshold responses in the corneally recorded electroretinogram elicited by multispot patterns. Clin Vis Sci 3, 29-44 (1988)
  9. O57 Zrenner E: Störungen der Zapfenfunktion und -interaktion. Spektrum Augenheilk 2, 44- 45 (1988)
  10. O56 Zrenner E, Ziegler R, Voss B: Clinical applications of pattern electroretinography: melanoma, retinal detachment and glaucoma. Doc Ophthalmol 68, 283-292 (1988)
  11. O55 Ulbig M, Zrenner E, Schneider T: Functional and morphological variations of fundus flavimaculatus. Doc Ophthalmol 67, 315-326 (1988)

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1987

  1. O54 Zrenner E: Are there separate channels for luminance and color? Die Farbe 34, 285-289 (1987)
  2. O53 Lorenz B, Zrenner E: [Why are myopic patients with choroid degeneration sensitive to glare?] German. Fortschr Ophthalmol. 84, 468-473 (1987)
  3. O52 Zrenner E, Baker C, Hess RF, Olsen BT: [Site of electroretinographic responses to pattern reversal and brightness stimuli in individual layers of the primate retina]. German. Fortschr Ophthalmol 84, 491-495 (1987)
  4. O51 Schneider T, Zrenner E: Rod-cone interaction in patients with fundus flavimaculatus. Brit J Ophthalmol 71, 762-765 (1987)
  5. O50 Schneider T, Zrenner E: The variable interdependence of amplitude and implicit-time in PIII, b-wave and optic nerve response. Exp Eye Res 45, 655-664 (1987)
  6. O49 Schneider T, Zrenner E [Differential diagnosis of early onset tapetoretinal degenerations using retinal functional diagnosis]. German. Fortschr Ophthalmol 84, 292-297 (1987)
  7. O48 Schneider T, Zrenner E: Double-flash responses in different retinal layers. Ophthalmic Res 19, 193-199 (1987)
  8. O47 Schneider T, Zrenner E: The effect of fluphenazine on rod-mediated retinal responses. Doc Ophthalmol 65, 287-296 (1987)

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1986

  1. O46 Zrenner E, Kohen L, Krastel H: [Limitation of retinal function in carriers of choroideremia]. German. Fortschr Ophthalmol 83, 602-608 (1986)
  2. O45 Schneider T, Zrenner E: [Independence of amplitudes, latency and spike behavior of retinal summation potentials]. German. Fortschr Ophthalmol 83, 702-705 (1986)
  3. O44 Zrenner E, Riedel KG, Adamczyk R, Gilg T, Liebhardt E: Effects of ethyl alcohol on the electrooculogram and color vision. Doc Ophthalmol 63, 305-312 (1986)
  4. O43 Hess RF, Baker CL, Zrenner E, Schwarzer J: Differences between electroretinograms of cat and primate. J Neurophysiol 56, 747-768 (1986)
  5. O42 Schneider T, Olsen BT, Zrenner E: Characteristics of the rod-cone transition in electroretinogram and optic nerve response. Clin Vis Sci 1, 81-91 (1986)
  6. O41 Schneider T, Zrenner E: The influence of phosphodiesterase inhibitors on ERG and optic nerve response of the cat. Invest Ophthal Vis Sci 27, 1395-1403 (1986)
  7. O40 Olsen BT, Schneider T, Zrenner E: Characteristics of rod driven off-responses in cat ganglion cells. Vision Res 26, 835-845 (1986)
  8. O39 Kohen L, Zrenner E, Schneider T: [Effect of theophylline and caffeine on sensory retinal function in the human]. German. Fortschr Ophthalmol 83, 338-344 (1986)
  9. O38 Zrenner E, Nowicki J, Adamczyk R: Cone function and cone interaction in hereditary degenerations of the central retina. Doc Ophthalmol 62, 5-12 (1986)

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1985

  1. O37 Zrenner E, Nowicki J: [Drug-induced functional disorders of cone function and cone interaction]. German. Fortschr Ophthalmol 82, 589-594 (1985)
  2. O36 Schneider T, Zrenner E: [The effect of phosphodiesterase inhibitors on retinal function of the eye undergoing arterial perfusion]. German. Fortschr Ophthalmol 82, 197-202 (1985)

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1984

  1. O35 Baier M, Zrenner E: Rechnergestützte Verfahren zur Klassifizierung von angeborenen und erworbenen Farbsinnstörungen. EDV in Medizin und Biologie 15 (3/4), 77-83 (1984)
  2. O34 Zrenner E, Lund OE: [Increased radiation exposure of the retina following implantation of intraocular lenses and its prevention using colorless filter glasses]. German. Klin Mbl Augenheilk 184, 193-196 (1984)
  3. O33 Krüger J, Zrenner E: Hypothesis relating the blue-sensitive cone mechanism to surround excitation of primate retinal off-centre neurons. Ophthalmic Res 16, 36-39 (1984)
  4. O32 Wienrich M, Zrenner E: Cone mechanisms and their colour-opponent interaction in monkey and cat. Ophthalmic Res 16, 40-47 (1984)

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1983

  1. O31 Zrenner E, Nelson R, Mariani A: [Biplexiform ganglion cells of the primate retina with direct contact with photoreceptors]. German. Fortschr Ophthalmol 80, 516-519 (1983)
  2. O30 Zrenner E, Nelson R, Mariani A: Intracellular recordings from a biplexiform ganglion cell in macaque retina, stained with horseradish peroxidase. Brain Res 262, 181-185 (1983)

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1982

  1. O29 Zrenner E, Kramer W, Bittner Ch Bopp M, Schlepper M: Rapid effects on colour vision, following intravenous injection of a new, non glycoside positive inotropic substance (AR-L 115 BS). Doc Ophthalmol Proc Series 33, 493-507 (1982)
  2. O28 Zrenner E: Electrophysiological characteristics of the blue sensitive mechanism: test of a model of cone interaction under physiological and pathological conditions. Doc Ophthalmol Proc Series 33, 103-125 (1982)
  3. O27 Gouras P, Zrenner E: The neural organization of primate color vision. Color Research and Application 7, 205-208 (1982)
  4. O26 Zrenner E: Interactions between spectrally different cone mechanisms. On the clinical applicability of psychophysical and electrophysical tests. Doc Ophthalmol Proc Series 31, 287-296 (1982)

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1981

  1. O25 Zrenner E, Krüger CJ, Baier M: Die Veränderungen der spektralen Empfindlichkeit bei Ethambutolschäden. Ber Dtsch Ophthalmol 78, 1031-1037 (1981)
  2. O24 Kramer W, Thormann J, Schlepper M, Bittner Ch Zrenner E: Aktivitätsprofil von AR-L 115 BS bei therapie-refraktionärer kongestiver Kardiomyopathie (CC)und Herzgesunden (HG): Wirkungsverlust durch Ca2+-Antagonisten. Verh Dtsch Ges Inn Med 87, 446-450 (1981)
  3. O23 Gouras P, Zrenner E: Wavelength-dependent enhancement in brain and behaviour. Science 211, 732-733 (1981)
  4. O22 Zrenner E, Gouras P: Characteristics of the blue sensitive cone mechanism in primate retinal ganglion cells. Vision Res 21, 1605-1609 (1981)
  5. O21 Schuurmans RP, Zrenner E: Responses of the blue sensitive cone system from the visual cortex and the arterially perfused eye in cat and monkey. Vision Res 21, 1611-1615 (1981)
  6. O20 Gouras P, Zrenner E: Color coding in primate retina. Vision Res 21, 1591-1598 (1981)
  7. O19 Zrenner E, Krüger CJ: Ethambutol mainly affects the function of red/green opponent neurons. Doc Ophthalmol Proc Series 27, 13-25 (1981)
  8. O18 Schuurmans RP, Zrenner E: Chromatic signals in the visual pathway of the domestic cat. Doc Ophthalmol Proc Series 27, 27-40 (1981)

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1980

  1. O17 Diehl R, Zrenner E: Multispot stimuli reveal spatial organization in the human electroretinogram (ERG). Doc Ophthalmol Proc Series 23, 209-216 (1980)
  2. O16 Kojima M, Zrenner E: Determination of local thresholds in the visual field by recording the scotopic visually evoked cortical potential in man. Ophthalmic Res. 12, 1-8 (1980)

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1973 - 1979

  1. O15 Zrenner E: [Processing of color stimuli in the primate retina (proceedings)]. German. Klin. Mbl. Augenheilk. 174, 654-656 (1979)
  2. O14 Zrenner E, Gouras P: Blue-sensitive cones of the cat produce a rodlike electroretinogram. Invest. Ophthalmol. Visual Sci. 18, 1076-1081 (1979)
  3. O13 Gouras P, Zrenner E: Enchancement of luminance flicker by color-opponent mechanisms. Science 205, 587-589 (1979)
  4. O12 Zrenner E, Baier M: Einsatz eines Prozeßrechners für online Untersuchungen der lichtinduzierten elektrischen Antwort des menschlichen Auges. EDV in Medizin und Biologie 9, 41-46 (1978)
  5. O11 Hoffmann ML, Zrenner E, Langhof HJ: [The effect of the pupil as aperture and field stop on the various components of the human electroretinogram (author's transl)]. German. Graefes Arch. Clin. Exp. Ophthal. 206, 237-245 (1978)
  6. O10 Kojima M, Zrenner E: Off-components in response to brief light flashes in the oscillatory potential of the human electroretinogram. Graefes Arch. Clin. Exp. Ophthal. 206, 107-120 (1978)
  7. O9 Zrenner E: Influence of stimulus duration and area on the spectral luminosity function as determined by sensory and VECP measurements. Doc. Ophthalmol Proc Series 13, 21-30 (1977)
  8. O8 Kojima M, Zrenner E: Local and spatial distribution of photopic and scotopic responses in the visual field as reflected in the visually evoked cortical potential (VECP). Doc. Ophthalmol Proc Series 13, 31-40 (1977)
  9. O7 Zrenner E, Kojima M, Jankov E: [Studies of color perception by means of visually evoked cortical potentials (VECP)]. German. Ber Dtsch Ophthal Ges. 74, 727-732 (1977)
  10.   O6 Langhof HJ, Kojima M, Zrenner E: [Parameters of the off-effect in the human electroretinogram]. German. Ber Dtsch Ophthal Ges 74, 739-742 (1977)
  11.   O5 Kojima M, Zrenner E, Langhof H-J: [The effect of stimulatory light intensity and duration of the preceding dark phase on the oscillatory potential in the human electroretinogram]. German. Ber Dtsch Ophthal Ges 74, 733-738 (1977)
  12.   O4 Zrenner E, Kojima M: Colour vision mechanisms isolated by selective adaptation in normals and dichromats as detected by the visually evoked cortical potential (VECP) Doc. Ophthalmol Proc Series 11, 115-121 (1977)
  13.   O3 Zrenner E, Langhof HJ, Welt R, Kojima M: [Electro-ophthalmological observations on the course of unilateral tapetoretinal degenerations (author's transl)]. German. Klin Monbl Augenheilkd. 1976 Sep; 169(3):331-7. (1976)
  14.   O2 Zrenner E, Kojima M: Visually evoked cortical potential (VECP) in dichromats. Mod Probl Ophthal 17, 241-246 (1976)
  15.   O1 Krüger H, Moser EA, Zrenner E: Influence of defocussing on retinal images of test patterns calculated with the modulation transfer function.Ophthal Res 5, 331-341 (1973)

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