Schnichels Lab
Neuroprotection & Drug Delivery
Home » Labs » Clinical Research Labs » Schnichels Lab » Members » José Hurst
José Hurst
| Surname | Hurst |
|---|---|
| First name | José |
| Nationality | German |
| Present position and title | Dr.rer.nat PostDoc |
Business address
Institute for Ophthalmic Research
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,
Germany
Phone: +49 (0)7071 29 87883
Fax: +49 (0)7071 29 25241
E-mail: jose.hurst[at]med.uni-tuebingen.de
Academic Education
| Year | Degree | University | Field of study |
|---|---|---|---|
| 10/2008 – 02/2013 | PhD (Dr. rer. nat.) | University of Tuebingen, Germany | Experimental virology and oncology |
| 10/2003 - 07/2008 | Diploma of Human biology | University of Greifswald, Germany | Immunology, Virology and Biochemistry |
| 02/2007 - 04/2007 | Internship | Burnet Institute for Medical Research and Public Health, Melbourne, Australia | Influence of Ca+ release on Lentivirus particle formation |
Professional Experience
| Period | Institution | Position | Discipline |
|---|---|---|---|
| 03/2014 - present | Schnichels Lab, University Eye Hospital Tübingen | Postdoctoral Research Fellow | Drug delivery, retinal degeneration models, Glaucoma |
| 03/2013 - 02/2014 | Thermo Fisher Scientific Inc. | Key Account and Product Development Manager | PCR and ELISA Development for viral diagnostics |
Professional Activities and Functions
Academic Teaching and Services
| Since 2018 | TüREX Program |
|---|---|
| Since 2016 | Studienpatenprogramm für Humanmediziner (Mentoring) |
Past and Current Funding
| 2017-2019 | Entwicklung von Alternativmethoden zur Vermeidung von Tierversuchen des Landes Baden-Württemberg: „Etablierung einer retinalen Ganglienzelllinie“ |
|---|---|
| 2017-2018 | Research grant from the PRO RETINA-Stiftung, Germany |
| 2017-2018 | Ernst und Berta Grimmke Stiftung: „Validierung von Kanamycin beladenen Nanopartikeln zur Behandlung von Augeninfektionen" |
Memberships
- Association for Research in Vision and Ophthalmology (ARVO)
- International Society for Eye Research
- Deutsche Ophthalmologische Gesellschaft (DOG)
Selected Publications
- J. Hurst, K. Hofmann, M. Vitkute, S. Müller, M. Löscher, K.U. Bartz-Schmidt, M. S. Spitzer, S. Schnichels&, K. Januschowski& Comparison of Different Cell Culture Media in the Model of the Isolated and Superfused Bovine Retina: Investigating the Limits of More Physiological Perfusion Solutions Curr Eye Res. 2017
- J. Hurst*, S. Kuehn*, A. Jashari, K. Ahrens, T. Tsai, I. Wunderlich, H. Burkhard Dick, S. Schnichels, S. Joachim A novel ex-vivo retina culture model for oxidative stress induced by H2O2 Altern Lab Anim. 2017 Mar;45(1):11-25.
- J. Hurst, S. Schnichels, M. Spitzer, K.U. Bartz-Schmidt, M. Farecki, P. Szurman, K. Januschowski “Toxic effects of Acid violet-17 on different ocular cells” Curr Eye Res. 2017 Mar 30:1-6. doi: 10.1080/02713683.2017.1285942.
- S. Schnichels, N. Schneider, C. Hohenadl, J. Hurst, A. Schatz, K. Januschowski, MS. Spitzer „Efficacy of two different thiol-modified crosslinked hyaluronate formulations as vitreous replacement compared to silicone oil in a model of retinal detachment.“ PLoS One. 2017 Mar 1;12(3):e0172895. doi: 10.1371/journal.pone.0172895
- S. Kuehn*, J. Hurst*, F. Rensinghoff, T. Tsai, S. Grauthoff, Y. Satgunarajah, H. B. Dick, S. Schnichels, S.C. Joachim Degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model Exp Eye Res 2017 Jan 12. pii: S0014-4835(17)30023-4.
- S. Kuehn*, J. Hurst*, A. Jashari, K. Ahrens, T.Tsai, I.M. Wunderlich, H. B. Dick, S.C. Joachim and S. Schnichels. The Novel Induction of Retinal Ganglion Cell Apoptosis in Porcine Organ Culture by NMDA — An Opportunity for the Replacement of Animals in Experiments. Altern Lab Anim. 2016 Dec;44(6):557-568.
- D. Süsskind, J. Hurst, JM Rohrbach, S. Schnichels. Novel mouse model for primary uveal melanoma: a pilot study. Clin Exp Ophthalmol. 2016 Aug 9. doi: 10.1111/ceo.12814.
- M. Schultheiss, S. Schnichels, T. Hermann, J. Hurst, M. Feldkaemper, B. Arango-Gonzalez, M. Ueffing, KU. Bartz-Schmidt, G. Zeck & MS. Spitzer Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia. PLoS One. 2016 Feb 5;11(2):e0148616. eCollection 2016.
- S. Mariacher, M. Ebner, K. Januschowski, J. Hurst, S. Schnichels, P. Szurman. Investigation of a novel implantable suprachoroidal pressure transducer for telemetric intraocular pressure monitoring. Exp Eye Res. 2016 Oct;151:54-60. doi: 10.1016/j.exer.2016.07.016.
- K. Januschowski, S.Mueller, C. Krupp, MS. Spitzer, J. Hurst, M. Schultheiss, KU Bartz-Schmidt, P. Szurman, S. Schnichels Glutamate and hypoxia as a stress model for the isolated perfused vertebrate retina. J Vis Exp. 2015 Mar 22;(97). doi: 10.3791/52270
- J. Fertey, J Hurst, E. Straub, A. Schenker, T. Iftner, F. Stubenrauch "Growth inhibition of HeLa cells is a conserved feature of high-risk human papillomavirus E8^E2C proteins and can also be achieved by an artificial repressor protein." J Virol 85(6): 2918-2926 2011.
- J. Reiser, J. Hurst, M. Voges, P. Krauss, P. Münch, T. Iftner, F. Stubenrauch. "High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression." J Virol 85(21): 11372-11380 2011.
S. Finke, H. Granzow, J. Hurst, R. Pollin, TC. Mettenleiter Intergenotypic replacement of lyssavirus matrix proteins demonstrates the role of lyssavirus M proteins in intracellular virus accumulation. J Virol. 2010 Feb;84(4):1816-27. doi: 10.1128/JVI.01665-09.
José Hurst