Schraermeyer Lab
Experimental Vitreoretinal Surgery
Methodology
A broad range of experimental techniques is performed in our lab on experimental animals (mice, rats, rabbits, monkeys), ranging from surgery and drug treatment, in vivo diagnostics (OCT, SLO, ERG and VEP), and finally analysis of tissues (including from human donors) on histological, immunohistochemical and ultrastructural levels including immunogold and analytical electron microscopy.
A light microscopic composite image of choroidal neovascularisation (CNV) (magnification: x600). Toluidine blue-stained semithin (0.7 µm) sections from an AMD patient show thinned, distorted or ruptured (labelled by arrow heads) Bruch’s membrane (Bm) underlying exudates in the retina. Note the extensive degeneration of the neurosensory retina. Chor corresponds to choroid.