Rathbun Group

Experimentelle Retinale Prothetik

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Research Topics

The Experimental Retinal Prosthetics Group uses a systems biology approach to explore novel processing algorithms that may improve prosthetic visual perception.  Our primary goal is to connect prosthesis-mediated visual responses in the blind mouse retina and normal visual responses in the healthy mouse retina through a unifying theoretical framework that encompasses both existing computational models and empirical data.

In our lab, we apply the study of neural coding in the visual system to:

  1. understanding how visual images are processed in the healthy and degenerating mouse retina;
  2. understanding how retinal neurons respond to extracellular electrical stimulation; and
  3. applying this knowledge to applications in retinal neuroprostheses. 

Our research lies at the intersection of extracellular electrophysiology and systems-level computational modeling.  In order to investigate these topics in neural coding, we record the extracellular spike trains of large collections of identified retinal ganglion cells (RGCs) using microelectrode arrays (MEAs).