Ophthalmic and Physiological Optics recently published a review article, "Key Lines of Discovery in Myopia Research, by Frank Schaeffel, Jeremy A. Guggenheim, Richard A. Stone and Christine F. Wildsoet.

This concise and comprehensive review traces the most influential milestones that have shaped our understanding of myopia, from the discovery of visually guided eye growth mechanisms in animal models to groundbreaking insights into optical defocus, retinal biochemistry, and gene-environment interactions. It also covers the increasing global prevalence of myopia, the protective role of outdoor light exposure and the evolving strategies for myopia control, including novel lens designs and pharmacological approaches.

Prepared for the International Myopia Conference (IMC) 2024, this review serves as both a historical overview and a springboard for future research, emphasising the complex interplay between genetics, visual experience and environmental factors.

Link to the original review