Ophthalmic Research Symposia - ORS
Seminars with invited external experts.
Supported by the “Tistou & Charlotte Kerstan” Foundation
Liquid biopsy proteomics in translational ophthalmology
Julian Wolf’s research integrates multi-omics technologies and computational modeling to unravel the molecular complexity of the human eye and advance the understanding and treatment of retinal diseases.
November 13, 2025 | 1.30 p.m. | Seminar Room 2.330
Julian Wolf our guest from Klinik für Augenheilkunde, Universitätsklinikum Freiburg will have a presentation on
“Liquid biopsy and single-cell proteomics”
Research Interests: Julian Wolf’s research combines cutting-edge multi-omics technologies—including RNA sequencing, mass spectrometry, and spatially resolved single-cell analysis—with advanced computational and machine learning approaches to unravel the complexity of the human eye. His team has developed unique expertise in analyzing small and precious clinical samples, integrating large-scale molecular data to model cellular and disease processes in unprecedented detail.
This Systems Ophthalmology approach enables a deeper understanding of the molecular and cellular mechanisms driving retinal diseases such as age-related macular degeneration and diabetic retinopathy, which together represent the leading causes of irreversible blindness worldwide.
Julian Wolf’s work has led to the identification of novel biomarkers and therapeutic targets and has improved the translation of findings between human and mouse models. A key achievement is the creation of the Human Eye Transcriptome Atlas, a publicly accessible resource providing gene expression profiles from over 200 diverse ocular tissues to the scientific community.
