Dominic Knauer
| Surname | Knauer |
| First name | Dominic |
| Position and Title | Master student |
| Project | OPN1LW/OPN1MW Exon 3-haplotype-linked Splicing Defects and their Rescue by Antisense Oligonucleotides |
| Short Description | Distinct combinations of frequent variants in exon 3 of the human OPN1LW and OPN1MW genes induce splicing defects and have been associated with retinal disorders such as Blue Cone Monochromacy (BCM), Bornholm Eye Disease (BED) or X-linked Cone Dystrophy (XLCD). To investigate potential therapeutic strategies, my project aims to design Antisense Oligonucleotides (ASOs) and evaluate their ability to restore correct splicing. |
Business address
Molecular Genetics Laboratory
Institute for Ophthalmic Research
Centre for Ophthalmology,
University of Tübingen
Elfriede-Aulhorn-Strasse 7
D-72076 Tübingen,
Germany
Phone: +49 (0)7071 29-87618